Heinrich Heine University Düsseldorf

Structure-based protein encoder that voxelizes every heavy atom into a 3D grid, learning orientation-robust representations for protein function.

Self-supervised foundation model for human cortical cytoarchitecture, encoding histological brain sections into anatomically meaningful features.

Macrocyclic peptide binder design against protein targets, cyclizing a diffusion backbone generator's positional encoding so it closes rings.

Aligns structure, binding-pocket, text and molecular-dynamics encoders to a protein sequence anchor, giving frozen embeddings that transfer widely.