Academic

Shandong University

Chinese comprehensive research university; the School of Software and Joint SDU-NTU Centre for AI Research develop biological sequence analysis tools

Location: Jinan, China
Website
5 models(2 Imaging, 2 DNA & Gene, 1 Protein, 1 Language model)

Models (5)

CryoDiff

Shandong University

Released June 6, 2026

Uncertainty-aware diffusion model that enhances cryo-EM density maps while estimating voxel-wise confidence via Monte Carlo sampling.

Imaging

PathDiffusion

Shandong University

Released January 16, 2026

115

Evolution-guided diffusion model that generates temporal protein folding pathways, from unfolded chain to native state, rather than static structures.

Protein

Melody

Shandong University / University of Electronic Science and Technology of China / Chinese Academy of Sciences

Released November 23, 2025

A deep learning framework that predicts locus-specific DNA methylation across 39 human tissues from genomic sequence, with a scRNA-seq-augmented variant for unseen cell types.

DNA & Gene

EndoChat

Chinese University of Hong Kong / Huawei / Technical University of Munich / University of Strasbourg / Shandong University / Chinese Academy of Sciences

Released January 20, 2025

422050

Grounded multimodal large language model for endoscopic surgery, supporting visual dialogue, region-based question answering, and bounding-box grounding across surgical scene understanding tasks.

ImagingLanguage model

iDNA-ABF

Shandong University

Released October 17, 2022

13615

Multi-scale deep biological language model for interpretable prediction of three DNA methylation types (4mC, 5hmC, 6mA) across multiple species using adaptive multi-scale k-mer BERT encoders.

DNA & Gene