All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 7396 of 217 filtered models

  • GO-GPT

    122939
    Bowang LabMarch 20, 2026gene_ontologygenerativego_term_annotation+3

    Protein function prediction model that autoregressively generates Gene Ontology terms from amino acid sequence instead of classifying fixed labels.

    Protein
    55Openness
  • RNAGAN

    1
    The University of Hong KongMarch 20, 2026cancercell_type_annotationdata_generation+5

    Generative adversarial network trained on single-cell and bulk RNA-seq for sample stratification, marker analysis, and synthetic data generation.

    Single-cell
    60Openness
  • ChironRNA

    University of VirginiaMarch 19, 2026diffusiongenerativegraph_neural_network+3

    All-atom E(3)-equivariant diffusion model that refines RNA structures by resolving steric clashes and completing missing atoms.

    RNA
    19Openness
  • ATMOS

    4
    MilaMarch 18, 2026conformation_generationdiffusionfoundation_model+5

    Generative foundation model that produces atom-level molecular dynamics trajectories for protein monomers and protein-ligand complexes.

    Protein
    11Openness
  • PI-Mamba

    University of Illinois Urbana-ChampaignMarch 17, 2026de_novo_designflow_matchinggenerative+4

    Protein backbone design model pairing flow matching with a Mamba state-space backbone, generating long proteins in linear time with exact geometry.

    Protein
    23Openness
  • SCALE

    Shanghai AI LaboratoryMarch 17, 2026flow_matchingfoundation_modelgenerative+4

    Virtual cell foundation model predicting single-cell responses to genetic, chemical, and cytokine perturbations with conditional flow matching.

    Single-cell
    19Openness
  • NVIDIAMarch 16, 2026all_atomde_novo_designflow_matching+6

    Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.

    Protein
    68Openness
  • SpeciefAI

    University of EdinburghMarch 16, 2026antibodyantibody_designgenerative+5

    Transformer that generates multi-species antibody and nanobody framework regions at the mRNA level, conditioned on input CDRs, across six species.

    ProteinRNA
    46Openness
  • AnewOmni

    842
    Tsinghua University +1 otherMarch 15, 2026antibodyde_novo_designdiffusion+6

    All-atom generative foundation model that designs small molecules, peptides, and nanobodies against a target binding site from a single checkpoint.

    ProteinSmall molecule
    63Openness
  • University of Texas at Arlington +1 otherMarch 13, 2026gangenerativehistology+4

    Virtual staining model that generates four IHC markers, HER2, Ki67, ER, and PR, from H&E using a generator conditioned on a frozen UNI encoder.

    Pathology
    17Openness
  • Sun Yat-sen UniversityMarch 13, 2026drug_repurposingfoundation_modelgenerative+6

    Generative virtual-cell model predicting whole-transcriptome responses to unseen compounds and genetic perturbations, from cell lines to organoids.

    Single-cellSmall molecule
    29Openness
  • EvoFlows

    2
    CradleMarch 12, 2026antibodyflow_matchinggenerative+5

    Edit-based flow-matching model that proposes protein variants by learning insertions, deletions, and substitutions on a template sequence.

    Protein
    21Openness
  • InversePep

    Keshav Memorial Engineering CollegeMarch 10, 2026diffusiongenerativegraph_neural_network+4

    Diffusion generative model for structure-based peptide inverse folding, pairing a geometric GNN encoder with a Transformer denoiser.

    Protein
    10Openness
  • ProtNHF

    Oak Ridge National LaboratoryMarch 6, 2026de_novo_designflow_matchinggenerative+4

    Neural Hamiltonian flow for protein sequence generation with inference-time control over composition and net charge via analytical bias potentials.

    Protein
    64Openness
  • PerturbGen

    25
    Wellcome Sanger InstituteMarch 5, 2026cell_biologyfoundation_modelgene_expression+6

    Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cell trajectories over time.

    Single-cell
    72Openness
  • D3LM

    142
    Renmin University of ChinaMarch 2, 2026diffusiondnafoundation_model+6

    DNA foundation model using masked discrete diffusion to unify bidirectional sequence understanding and de novo generation in one architecture.

    DNA & Gene
    58Openness
  • RigidSSL

    201
    Chinese University of Hong KongMarch 2, 2026conformational_ensemble_generationflow_matchinggenerative+5

    Self-supervised SE(3) geometric pretraining for protein backbone generators, improving designability, motif scaffolding, and conformational ensembles.

    Protein
    73Openness
  • CellPace

    McGill UniversityFebruary 26, 2026cell_biologydiffusiongene_expression+5

    Temporal diffusion framework for single-cell developmental dynamics, interpolating and forecasting cell states from irregularly sampled time series.

    Single-cell
    9Openness
  • MilaFebruary 23, 2026diffusiongene_expressiongenerative+3

    Diffusion model predicting single-cell responses to genetic or drug perturbations, generating over distributions to capture population variability.

    Single-cell
    51Openness
  • PLUM

    1
    Iowa State UniversityFebruary 21, 2026antimicrobial_peptidesde_novo_designgenerative+3

    Conditional variational autoencoder for antimicrobial peptide design that disentangles sequence, function, and length for independent control.

    Protein
    56Openness
  • PEINT

    6
    UC BerkeleyFebruary 20, 2026evolutionary_simulationgenerativemolecular_evolution+4

    Protein evolution model that learns indel dynamics and epistasis from unaligned sequences, simulating trajectories that yield functional proteins.

    Protein
    11Openness
  • University of BristolFebruary 19, 2026data_generationdiffusionfoundation_model+4

    Single-cell foundation model applying discrete diffusion directly to scRNA-seq counts, generating unconditional and perturbation-conditioned profiles.

    Single-cell
    10Openness
  • BOND-PEP

    University of SydneyFebruary 18, 2026de_novo_designgenerativepeptides+3

    Retrieval-augmented framework for de novo peptide binder design that conditions generation on retrieved, structurally aligned binding evidence.

    Protein
    5Openness
  • MMPT-RAG

    Emory UniversityFebruary 18, 2026drug_discoveryfoundation_modelgenerative+3

    Retrieval-augmented model for matched molecular pair transformations, proposing localized analog edits guided by retrieved reference compounds.

    Small molecule
    16Openness