All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 4972 of 316 filtered models

  • Mach-1

    34
    Broad InstituteApril 21, 2026foundation_modelisoform_abundance_predictionpre_mrna+8

    Long-context RNA foundation model that predicts splicing, isoform abundance, and variant effects from 64 kb of unspliced pre-mRNA sequence.

    RNA
    39Openness
  • Zhejiang Lab +1 otherApril 21, 2026chromatinchromatin_accessibilitydna+8

    Genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window and a 1.25B-parameter mixture-of-experts transformer.

    DNA & Gene
    90Openness
  • University of VirginiaApril 19, 2026diffusiongenerativegraph_neural_network+5

    RNA inverse folding framework pairing a graph neural network predictor with a diffusion model, designing sequences from self-contained RNA units.

    RNA
    17Openness
  • University of Texas at Austin +1 otherApril 17, 2026bertdrug_discoveryfoundation_model+7

    Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.

    Small moleculeProtein
    79Openness
  • xVERSE

    Duke UniversityApril 14, 2026batch_effect_correctionfoundation_modelgenerative+5

    Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.

    Single-cell
    10Openness
  • OmniNA

    3101
    Beijing Institute of Genomics +1 otherApril 13, 2026dnafoundation_modelgenome+7

    Generative DNA foundation model trained on 91.7M nucleotide sequences and annotations for species classification and mutation effect prediction.

    DNA & Gene
    42Openness
  • IDiom

    Chinese Academy of SciencesApril 11, 2026foundation_modelintrinsically_disordered_protein_designintrinsically_disordered_region+5

    Autoregressive language model trained on 37 million intrinsically disordered region sequences, generating IDRs given flanking folded domains.

    Protein
    19Openness
  • GenoJEPA

    Beijing University of Posts and TelecommunicationsApril 6, 2026foundation_modelgenomicsrepresentation_learning+4

    Genomic foundation model that learns DNA representations by predicting masked regions in latent space rather than reconstructing raw nucleotides.

    DNA & Gene
    22Openness
  • STORM

    3
    Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6

    Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.

    Spatial omicsPathology
    17Openness
  • PlantCAD2

    974.2K
    Cornell UniversityApril 3, 2026foundation_modelfunctional_annotationgene_expression+7

    Long-context plant DNA language model, 676M parameters on a Mamba2 backbone, pretrained on 65 angiosperm genomes for cross-species variant annotation.

    DNA & Gene
    69Openness
  • GATSBI

    13
    Stanford UniversityApril 3, 2026embeddingsfunction_predictiongraph_attention_network+4

    Graph attention model that learns context-aware protein embeddings from protein-protein interaction, co-expression, and tissue association networks.

    Protein
    94Openness
  • muat

    8
    University of HelsinkiApril 3, 2026attentioncancer_genomicsrepresentation_learning+5

    Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.

    DNA & Gene
    65Openness
  • Chinese Academy of SciencesApril 2, 2026codoncodon_optimizationfoundation_model+8

    Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.

    RNA
    10Openness
  • scLong

    2210
    Chinese Academy of SciencesApril 1, 2026batch_integrationcell_type_annotationfoundation_model+5

    Billion-parameter single-cell foundation model with self-attention over 28,000 human genes, adding Gene Ontology priors via a graph neural network.

    Single-cell
    29Openness
  • Digepath

    Chinese Academy of SciencesApril 1, 2026cancer_diagnosisfoundation_modelgastrointestinal_cancer+7

    Gastrointestinal histopathology foundation model pretrained on 353 million multi-scale patches from 210,000 H&E whole-slide images of GI tissue.

    Pathology
    15Openness
  • RegFormer

    BGI ResearchApril 1, 2026batch_integrationcell_clusteringdrug_response_prediction+5

    Single-cell foundation model combining regulatory network priors with a Mamba backbone for clustering, batch integration, and perturbation modeling.

    Single-cell
    10Openness
  • AINN-P1

    AinnocenceMarch 30, 2026language_modellstmprotein_fitness_prediction+3

    Compact 167M-parameter protein language model built on a multiplicative LSTM, giving zero-shot variant effect and fitness prediction from sequence.

    Protein
    12Openness
  • Carnegie Mellon UniversityMarch 27, 2026brain_computer_interfaceeegfoundation_model+5

    EEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.

    Biosignals
    18Openness
  • EVA

    821
    GENTEL LabMarch 24, 2026aptameraptamer_designcircular_rna+9

    Generative RNA foundation model trained on 114 million full-length sequences for de novo design of tRNAs, aptamers, CRISPR guide RNAs, and mRNAs.

    RNA
    72Openness
  • Golab (SAIS Physics Lab)March 23, 2026diffusiondrug_discoveryfoundation_model+4

    Molecular foundation models pretrained on density functional theory data, encoding 3D geometry and quantum behavior for ADMET and drug discovery.

    Small molecule
    46Openness
  • genbio.aiMarch 20, 2026foundation_modelhistologyrepresentation_learning+3

    Histopathology foundation model with 1.1B parameters, trained entirely on public data using JEDI, a dual-stage strategy combining JEPA and DINO.

    Pathology
    21Openness
  • ProteinSage

    BioMapMarch 19, 2026foundation_modelprotein_structurerepresentation_learning+3

    Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.

    Protein
    12Openness
  • RNAElectra

    Australian National UniversityMarch 17, 2026foundation_modelself_supervisedstructure_prediction+1

    Single-nucleotide-resolution RNA foundation model pretrained on non-coding RNAs with ELECTRA-style replaced-token detection for regulatory inference.

    RNA
    23Openness
  • X-Cell

    1068
    Xaira TherapeuticsMarch 17, 2026crispr_perturbationdiffusionfoundation_model+4

    Diffusion language model with 4.9 billion parameters that predicts genome-wide CRISPRi perturbation responses in single-cell transcriptomes.

    Single-cell
    20Openness