Generative image perturbation autoencoder predicting cellular morphological responses to chemical and genetic perturbations from control images.
Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.
Spatial proteomics foundation model, marker-aware and panel-agnostic, pretrained on 47 million multiplexed tissue-imaging patches from 175 markers.
Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.
Cell Painting image encoder that turns whole-slide multi-channel microscopy into morphological profiles in one pass, with no cell segmentation step.
Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.
Transformer that predicts gene expression and epigenomic signals from 200kb of DNA sequence, capturing distal enhancers up to 100kb from a promoter.
Genomic prediction model for plant and animal breeding, pretrained entirely on simulated populations and deployed with no training or tuning.
Spatial proteomics foundation model for multiplex immunofluorescence, with a 268-marker vocabulary and marker-conditioned 768-dimensional embeddings.
Transcriptome-guided diffusion model generating Cell Painting images for unseen perturbations, improving MOA retrieval accuracy by 16.9% over IMPA.
Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.
Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.
Virtual cell transformer that predicts how cells respond to genetic, chemical, or signaling perturbations, generalizing to unseen cellular contexts.
Spatial transcriptomics foundation model pairing gene-scale cell embeddings with an SE(2) Transformer over cell coordinates, pretrained on 88M cells.
Self-supervised foundation model that embeds cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types for tumor subtyping.
Spatial transcriptomics language model that reads tissue as spatial sentences to simulate cell profiles and run in silico perturbations.
Supervised variational autoencoder that learns a tissue-aware latent space for bulk RNA-seq, trained on harmonized TCGA, GTEx, and ARCHS4 data.
Perturbation prediction model that forecasts transcriptional responses to multi-gene CRISPR perturbations from scRNA-seq and a gene-gene graph.
Enhancer-promoter interaction prediction from DNA sequence and ATAC-seq alone. Spearman above 0.90 on cell types unseen during training.
Generative antibody model that produces light-chain sequences conditioned on a heavy chain, pairing a RoBERTa encoder with a GPT-2 decoder.
MSA-free protein structure prediction that replaces multiple sequence alignments with a protein language model pre-trained on billions of sequences.