All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 98 filtered models
MolSight
———Renmin University of ChinaJuly 2, 2026graph_neural_networkmultimodaloptical_chemical_structure_recognition+2Vision-language model that reads molecular structure images, translating them to SMILES, captions, and properties via chemical-bond topology.
Small moleculeLanguage model21OpennessProLoc
———Text-guided localization model that grounds natural-language functional descriptions to specific residue regions of a protein sequence.
ProteinLanguage model10OpennessSingle-cell language model that prepends biomedical knowledge-graph tokens to cell sentences, grounding cell type annotation in pathway structure.
Single-cellLanguage model23OpennessBioMatrix
41—162Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.
ProteinSmall moleculeLanguage model67OpennessBacteReason
———University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5Reasoning LLM that predicts antimicrobial susceptibility of clinical bacterial isolates and supplies mechanistic explanations for each prediction.
DNA & GeneLanguage model20OpennessAMix-2
———Protein-text foundation model placing amino acid sequences and natural language in one token space for protein understanding and de novo design.
ProteinLanguage model10OpennessBio-BLIP
———Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.
DNA & GeneLanguage model23OpennessOmniGene-4
———Unified bio-language Mixture-of-Experts model spanning DNA, protein sequence and structure, and biological text across eight task families.
Language modelDNA & GeneProtein7OpennessCellPulse
———Direction-aware foundation model trained on bulk RNA-seq differential-expression profiles to simulate coordinated gene dynamics in viral infection.
Single-cellLanguage model4OpennessMMPT-FM
389—Chemical language model that generates matched molecular pair transformations from SMILES and SMARTS to design medicinal-chemistry analogs.
Small moleculeLanguage model82OpennessGPT-Rosalind
4.6K——OpenAI's frontier reasoning model for life-sciences research, tuned for multi-step workflows in protein engineering, genomics, and drug discovery.
Language model5OpennessBioReason-Pro
1209—Multimodal reasoning LLM for protein function prediction, fusing protein language model embeddings to emit interpretable GO-term reasoning traces.
ProteinLanguage model58OpennessMolecular reasoning model built on DeepSeek-7B, using chain-of-thought and reinforcement learning for property prediction, generation, and reactions.
Small moleculeLanguage model21OpennessSmall-molecule drug discovery foundation model covering ADMET, retrosynthesis, drug-target activity, and molecular optimization in a 2.6B checkpoint.
Small moleculeLanguage model7OpennessLarge language model trained on functional genomics data to prioritize novel therapeutic targets from genome-wide CRISPR knockout screens.
DNA & GeneLanguage model12OpennessNeuroVLM
8——Vision-language foundation model linking human brain activation maps and neuroscience text for text-to-brain and brain-to-text generation.
ImagingLanguage model74OpennessBioBridge
—2—Connects a frozen protein language model to a general LLM via a cross-modal projector, adding protein reasoning without catastrophic forgetting.
Language modelProtein13OpennessOKR-CELL
———Cross-modal single-cell foundation model that aligns gene-expression profiles with LLM-enriched cell descriptions in a shared embedding space.
Single-cellLanguage model23OpennessCMAP
———Antibody developability predictor pairing text and protein language models, using in-context learning to fit new assays without retraining.
ProteinLanguage model4OpennessBiomeGPT
—1—Massachusetts General HospitalJanuary 5, 2026biomarker_discoverydisease_classificationfoundation_model+6Gut microbiome foundation model pretrained on human shotgun metagenomes, learning species-level taxonomic representations for disease prediction.
DNA & GeneLanguage model8OpennessNetMedGPT
—2—Transformer foundation model pretrained on a biomedical knowledge graph for zero-shot drug repurposing, target, and adverse-effect prediction.
Language modelSmall molecule24OpennessMerlin
452517.2K3D vision-language foundation model for abdominal CT, pretrained on scans, radiology reports, and EHR codes for zero-shot interpretation.
ImagingLanguage model54OpennessscMOBA
—11—Chinese Academy of Sciences +1 otherDecember 2, 2025cell_biologycell_type_annotationdata_integration+5Conversational single-cell and spatial multi-omics brain foundation model, with zero-shot cell annotation and disease prediction across species.
Single-cellLanguage model5OpennessH3BERTa
13978Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.
ProteinLanguage model83Openness