All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 38 filtered models
GPFlow
———Variable-length generative protein design across structure, sequence, motif scaffolding, and peptide co-design via a generalized Poisson flow.
Protein18OpennessNavigo
12——Chinese University of Hong Kong +1 otherJune 24, 2026cell_fate_engineeringflow_matchinggene_regulatory_network_inference+6Generative framework that learns a developmental vector field from scRNA-seq snapshots, coupling flow matching with molecular RNA kinetics.
Single-cellRNA44OpennessVelocityFM
———University of Colombo School of Computing +1 otherJune 7, 2026conformational_samplingflow_matchinggenerative+4Generative protein-dynamics model that predicts short molecular dynamics trajectories with rectified flow matching over residue frames and torsions.
Protein21OpennessFlowTransOP
———Flow-matching framework that translates omics signatures across biological domains, such as mouse to human transcriptomics, without paired samples.
Single-cell87OpennessLineageFlow
3——Dirichlet flow-matching model for protein design that generates family-aware sequences from ancestral-reconstruction priors, not random noise.
Protein64OpennessDCFold
—2—Protein structure prediction and binder design in a single generative step, replacing AlphaFold3's iterative diffusion sampling with one forward pass.
Protein16OpennessPhoenix
———Virtual spatial transcriptomics foundation model predicting pan-cancer, spatially-resolved single-cell gene expression from H&E histology slides.
PathologySpatial omics8OpennessAF2Dock
151—Protein-protein docking model adapting AlphaFold-Multimer with a docking module and flow-matching training to assemble subunits without MSAs.
Protein77OpennessPI-Mamba
———Protein backbone design model pairing flow matching with a Mamba state-space backbone, generating long proteins in linear time with exact geometry.
Protein23OpennessSCALE
———Virtual cell foundation model predicting single-cell responses to genetic, chemical, and cytokine perturbations with conditional flow matching.
Single-cell19OpennessProteina-Complexa
39821148Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.
Protein68OpennessProtNHF
———Neural Hamiltonian flow for protein sequence generation with inference-time control over composition and net charge via analytical bias potentials.
Protein64OpennessRigidSSL
201—Chinese University of Hong KongMarch 2, 2026conformational_ensemble_generationflow_matchinggenerative+5Self-supervised SE(3) geometric pretraining for protein backbone generators, improving designability, motif scaffolding, and conformational ensembles.
Protein73OpennessProtFlow
—2—Flow-matching generative model for peptide sequence design that learns the protein semantic distribution, fine-tuned for antimicrobial peptides.
Protein16OpennessDERIVE
———Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.
Protein16OpennessscDFM
447—Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.
Single-cell54OpennessCHASE
———Latent flow-matching method that repurposes protein language model embeddings to generate high-fitness protein variants without predictor guidance.
Protein11OpennessMoLF
———Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.
PathologySpatial omics9OpennessLa-Proteina
304—142Partially latent flow-matching model for de novo protein design, jointly generating sequence and all-atom structure for proteins up to 800 residues.
Protein69OpennessPPIFlow
—4—Flow-matching generative model for de novo protein binder backbone design, built on a Pairformer architecture with in silico interface maturation.
Protein4OpennessSurfFlow
—6—Flow-matching model for therapeutic peptide design that co-designs sequence, structure, and molecular surface to disrupt protein-protein interactions.
ProteinSmall molecule18OpennessOMTRA
68——Structure-based drug design model that unifies de novo generation, docking, conformer generation, and pharmacophore conditioning via flow matching.
Small moleculeProtein72OpennessRFdiffusion2
439114—Atom-level diffusion model for de novo enzyme design that scaffolds arbitrary active-site geometries without specifying catalytic residue positions.
Protein69Openness