All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 31 filtered models
RepGene
———Gene representation framework fusing DNA, transcript, protein, text, and single-cell embeddings into one latent space that survives missing views.
DNA & GeneProteinSingle-cell22OpennessTxFM
2——Transcriptomics foundation model from Recursion that masks and reconstructs RNA-seq gene expression counts to learn reusable sample embeddings.
Single-cell12OpennessFlowTransOP
———Flow-matching framework that translates omics signatures across biological domains, such as mouse to human transcriptomics, without paired samples.
Single-cell87OpennessSE(3)-invariant masked autoencoder that learns protein fold representations from AlphaFold-DB structures, supporting zero-shot fold classification.
Protein78OpennessPLM-SAE
———Sparse autoencoders trained on protein language model embeddings to expose interpretable features and drive zero-shot variant effect prediction.
Protein22OpennessNeuroVLM
8——Vision-language foundation model linking human brain activation maps and neuroscience text for text-to-brain and brain-to-text generation.
ImagingLanguage model74OpennessProtein structure tokenizer that encodes a whole structure globally, with each successive token adding detail for adaptive-length representations.
Protein6OpennessCHASE
———Latent flow-matching method that repurposes protein language model embeddings to generate high-fitness protein variants without predictor guidance.
Protein11OpennessISTS
———Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.
Single-cellDNA & Gene20OpennessEvoSynth
8——Multi-target drug discovery framework pairing a diffusion-transformer generator with evolutionary latent-space search and synthesis-aware scoring.
Small molecule51OpennessscLDM
587—Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.
Single-cell75OpennessscLDM.CD4
9—198Single-cell latent diffusion model fine-tuned on 14.5 million CD4+ T cells to simulate transcriptomic effects of single-gene perturbations.
Single-cell75OpennessCellTok
———Multimodal LLM that tokenizes single cells into discrete VQ-VAE codebook tokens, letting one model reason jointly over transcriptomes and text.
Single-cellLanguage model20OpennessProteinAE
212—Protein structure autoencoder compressing backbone coordinates into a latent space, paired with a latent diffusion model for generative design.
Protein74OpennessMagicDock
———De novo ligand design framework that generates protein binders and small molecules by inverting gradients through a differentiable docking model.
ProteinSmall molecule33OpennessSLAE
———All-atom protein representation model that learns from each residue's strictly local atomic neighborhood, capturing side-chain geometry and chemistry.
Protein20OpennessTahoe-100M-SCVI
1.7K123—scVI variational autoencoder trained on the Tahoe-100M drug-perturbation atlas, giving a 10-dimensional embedding of treated cancer cell states.
Single-cell93OpennessSCimilarity
258125—Single-cell foundation model trained by metric learning to embed scRNA-seq profiles for cell type annotation and similarity search in cell atlases.
Single-cell78OpennessD-BETA
3613120Singapore Management University +1 otherOctober 3, 2024autoencodercontrastive_learningecg_classification+6ECG foundation model pretrained on 12-lead waveforms paired with clinical reports, enabling label-efficient and zero-shot cardiac diagnosis.
BiosignalsLanguage model27OpennessscVI (CELLxGENE Census)
1.7K2.4K—Variational autoencoder pretrained on 74 million human single-cell transcriptomes from the CELLxGENE Census for batch correction and cell typing.
Single-cell96OpennessBrainMAE
—10—Self-supervised masked autoencoder for functional MRI that learns representations from BOLD time-series with per-ROI embeddings and graph attention.
Biosignals17OpennessOPERA
8346—Respiratory acoustic foundation models pretrained on roughly 136K cough and breathing recordings for disease detection and lung function estimation.
Biosignals59Openness