Pennsylvania State University

Contrastive multimodal model for perturbation screens, aligning transcriptomic signatures with text and cell-painting image embeddings.

Photoplethysmography foundation model pretrained by reconstructing masked ECG from PPG, learning cardiac timing structure for wearable health tasks.

DNA sequence embedding model that approximates edit distance via contrastive fine-tuning of DNABERT-2, improving similar-sequence search accuracy.

Protein-protein binding affinity prediction from sequence alone, pairing frozen protein language model embeddings with gradient-boosted trees.

Protein-ligand binding affinity prediction for Kd, Ki and IC50 from a pocket structure and a SMILES string, with no docked complex required.

Self-supervised masked autoencoder for functional MRI that learns representations from BOLD time-series with per-ROI embeddings and graph attention.