All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 193–216 of 552 filtered models
EXAONE Path 2.5
5280Pathology foundation model that aligns whole-slide images with genomic, epigenetic, and transcriptomic data for patient-level tumor representations.
PathologySpatial omics14OpennessGlycanGT
3——Graph transformer foundation model for glycans, learning reusable embeddings of branched carbohydrate structures for glycomics prediction tasks.
Small molecule82OpennessOmniNovo
———Fudan University +8 othersDecember 13, 2025de_novo_peptide_sequencingfoundation_modelmass_spectrometry+4De novo peptide sequencing transformer that reads modified and unmodified peptides directly from tandem mass spectra without a reference database.
Protein14OpennessEva
—4—Enable Medicine +4 othersDecember 12, 2025cell_type_annotationcross_modal_inferencefoundation_model+8Tissue imaging foundation model pretrained on matched H&E histology and spatial proteomics for cross-modal inference and zero-shot retrieval.
PathologySpatial omics4Opennessvir2vec
31388Pan-viral genomic language model producing fixed genome-level embeddings of viral DNA and RNA, reused across classification tasks without retraining.
DNA & Gene53OpennessPlantBiMoE
8—6Plant genome foundation model pairing a bidirectional Mamba backbone with sparse Mixture-of-Experts, pretrained on 25.4B nucleotides from 42 species.
DNA & Gene53OpennessOMTRA
68——Structure-based drug design model that unifies de novo generation, docking, conformer generation, and pharmacophore conditioning via flow matching.
Small moleculeProtein72OpennessPanFoMa
2——Pan-cancer single-cell foundation model with a hybrid Transformer-Mamba architecture, released with the PanFoMaBench cancer evaluation benchmark.
Single-cell13OpennessISTS
———Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.
Single-cellDNA & Gene20OpennessscMOBA
———Chinese Academy of Sciences +1 otherDecember 2, 2025cell_biologycell_type_annotationdata_integration+5Conversational single-cell and spatial multi-omics brain foundation model, with zero-shot cell annotation and disease prediction across species.
Single-cellLanguage model5OpennessCLEF
554—Single-lead ECG foundation model pretrained on 12-lead recordings, weighting contrastive pairs by clinical risk for cardiovascular risk prediction.
Biosignals62OpennessCellHermes
30276Single-cell foundation model adapting LLaMA-3.1-8B with LoRA, recasting transcriptomes and protein interaction networks as natural-language Q&A pairs.
Single-cellRNA55OpennessPULSAR
364166Hierarchical single-cell foundation model that turns scRNA-seq profiles into zero-shot donor-level embeddings for disease and biomarker prediction.
Single-cellProtein58OpennessRNA-X
41—RNA interaction foundation model for conditional, zero-shot design of RNA sequences that bind protein, DNA, or RNA targets without retraining.
RNAProtein6OpennesseccDNAMamba
5——Bidirectional state-space (Mamba-2) genomic model for ultra-long extrachromosomal circular DNA, scaling linearly with sequence length.
DNA & Gene54Openness- University of Maryland, College ParkNovember 24, 2025codon_optimizationde_novo_designfoundation_model+6
Conditional codon language model with 150M parameters that generates species-optimized coding sequences from a protein and its taxonomic lineage.
DNA & GeneRNA90Openness NeuroVFM
554654University of Michigan +1 otherNovember 23, 2025ctfoundation_modeljoint_embedding_predictive_architecture+8Generalist neuroimaging vision foundation model pretrained on 5.24M clinical MRI and CT volumes for radiologic diagnosis and report generation.
Imaging57OpennessPuget
———Gene expression prediction model combining DNA sequence with Hi-C contact maps to capture 3D chromatin looping behind cell-type-specific expression.
DNA & Gene8OpennessEvo2HiC
102—University of WashingtonNovember 19, 2025chromatinchromatin_contact_predictionepigenomic_profiling+9Multimodal foundation model that distills Evo 2 into a compact encoder guided by Hi-C data, predicting cell-type-specific 3D genome architecture.
DNA & GeneSpatial omics57OpennessUni-Hema
—1—Information Technology University of the Punjab +1 otherNovember 18, 2025classificationcnnfoundation_model+8Digital hematopathology foundation model unifying blood-cell detection, classification, segmentation, and visual question answering.
Pathology8OpennessMergeDNA
—5—Hierarchical DNA foundation model that co-trains a dynamic token-merging tokenizer with latent Transformers to match genomic information density.
DNA & Gene5Openness