All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 169–192 of 943 models
Protein function prediction model that fuses sequence, structure, text, and interaction embeddings with learned gating to assign Gene Ontology terms.
Protein84OpennessPeptideCLM-2
101—Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.
Small moleculeProtein79OpennessGPT-Rosalind
4.6K——OpenAI's frontier reasoning model for life-sciences research, tuned for multi-step workflows in protein engineering, genomics, and drug discovery.
Language model5OpennessDIA-CLIP
———AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.
Protein11OpennessEncoder-decoder Transformer that generates intrinsically disordered protein sequences conditioned on target conformational-ensemble descriptors.
Protein10OpennessLinkLlama
101.9K13Molecular linker design model fine-tuned from Llama 3 that emits PROTAC and fragment linkers as SMILES from natural-language geometry prompts.
Small molecule27OpennessGerminal
27134—Generative pipeline for epitope-targeted de novo antibody (nanobody) CDR design that yields nanomolar binders from only dozens of designs per antigen.
Protein37OpennessxVERSE
—29—Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.
Single-cell10OpennessOmniNA
——100Generative DNA foundation model trained on 91.7M nucleotide sequences and annotations for species classification and mutation effect prediction.
DNA & Gene42OpennessIDiom
—1—Chinese Academy of SciencesApril 11, 2026foundation_modelintrinsically_disordered_protein_designintrinsically_disordered_region+5Autoregressive language model trained on 37 million intrinsically disordered region sequences, generating IDRs given flanking folded domains.
Protein19OpennessDeep-Plant
1——Chromatin-informed foundation model predicting regulatory activity and chromatin state directly from plant genomic sequence in Arabidopsis and rice.
DNA & Gene87OpennessProtenix-v2
2K6—464M-parameter structure prediction and design model that improves antibody-antigen complex accuracy over Protenix-v1 and adds generative VHH design.
Protein81OpennessDISCO
2083—Multimodal diffusion model that co-designs protein sequence and 3D structure around cofactors and small molecules for de novo heme enzyme design.
Protein70OpennessGenoJEPA
—21—Beijing University of Posts and TelecommunicationsApril 6, 2026foundation_modelgenomicsrepresentation_learning+4Genomic foundation model that learns DNA representations by predicting masked regions in latent space rather than reconstructing raw nucleotides.
DNA & Gene22OpennessHalo
———Whole-cell segmentation model for spatial transcriptomics that fuses DAPI nuclear images with RNA transcript density to recover true cell boundaries.
Spatial omics63OpennessMuPD
—280—Diffusion-transformer pathology model embedding H&E histology, RNA profiles, and clinical text in a latent space for zero-shot cross-modal synthesis.
PathologySpatial omics15OpennessSTORM
—2—Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.
Spatial omicsPathology17OpennessPlantCAD2
97—2.8KLong-context plant DNA language model, 676M parameters on a Mamba2 backbone, pretrained on 65 angiosperm genomes for cross-species variant annotation.
DNA & Gene69Opennessseq2ribo
10365—Hybrid framework that predicts ribosome location profiles from mRNA sequence alone, pairing a structure-aware TASEP simulation with a Mamba polisher.
RNA18OpennessGATSBI
13——Graph attention model that learns context-aware protein embeddings from protein-protein interaction, co-expression, and tissue association networks.
Protein94Opennessmuat
8——Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.
DNA & Gene65OpennessmRNA-GPT
41—Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.
RNA10OpennessscLong
2110—Billion-parameter single-cell foundation model with self-attention over 28,000 human genes, adding Gene Ontology priors via a graph neural network.
Single-cell29OpennessDiscrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.
DNA & Gene49Openness