All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 121144 of 943 models

  • TD3B

    2
    Duke UniversityMay 15, 2026de_novo_designdiffusionfine_tuning+4

    Sequence-based discrete-diffusion framework that designs peptide binders with specified agonist or antagonist behavior against GPCR targets.

    Protein
    10Openness
  • Bio-BLIP

    Stanford UniversityMay 15, 2026foundation_modelgenomicsmendelian_disease+7

    Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.

    DNA & GeneLanguage model
    23Openness
  • PLM-SAE

    Shanghai Smart Logic Technology Co., Ltd.May 15, 2026autoencoderproteomicsrepresentation_learning+3

    Sparse autoencoders trained on protein language model embeddings to expose interpretable features and drive zero-shot variant effect prediction.

    Protein
    22Openness
  • ProtLiD

    6
    National University of SingaporeMay 15, 2026de_novo_designdiffusiongenerative+6

    370M-parameter ligand-conditioned discrete diffusion model that co-designs protein sequence and structure under explicit small-molecule constraints.

    Protein
    5Openness
  • University of CopenhagenMay 14, 2026foundation_modelsegmentationtransfer_learning+2

    Domain-specific foundation model for zero-shot plant root image segmentation, built on a MobileSAM backbone and trained across nine root datasets.

    Imaging
    74Openness
  • SpaRank

    Guangxi UniversityMay 13, 2026foundation_modelmultimodalspatial_transcriptomics+2

    Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.

    Spatial omics
    8Openness
  • ENSEMBITS

    7
    Vanderbilt UniversityMay 13, 2026function_predictionmolecular_dynamicsprotein_dynamics+5

    Protein conformational ensemble tokenizer that learns a discrete alphabet of states from molecular dynamics, reusable as a frozen feature layer.

    Protein
    66Openness
  • RedNet

    4
    Toyota Technological Institute at ChicagoMay 13, 2026generativegraph_neural_networkinverse_folding+3

    Multiscale graph neural network for fixed-backbone protein binder sequence design with a contrastive decoding algorithm to improve target selectivity.

    Protein
    83Openness
  • MuseDrift

    University of Florida +1 otherMay 12, 2026de_novo_designdiffusiongenerative+3

    Conditional discrete diffusion model for protein variant generation, with a calibrated identity dial controlling drift from a wild-type sequence.

    Protein
    12Openness
  • OmniGene-4

    Huazhong University of Science and TechnologyMay 12, 2026dnafoundation_modelinstruction_following+7

    Unified bio-language Mixture-of-Experts model spanning DNA, protein sequence and structure, and biological text across eight task families.

    Language modelDNA & GeneProtein
    7Openness
  • FLASH

    Hunter College, CUNYMay 11, 2026drug_discoverydrug_drug_interactiondrug_repurposing+7

    Signed heterogeneous graph foundation model over the SIGMA-KG knowledge graph, predicting drug mode of action and drug-drug interactions zero-shot.

    Small molecule
    10Openness
  • FiberLM

    2
    NYU Grossman School of MedicineMay 11, 2026connectomicsdiffusion_mriself_supervised+3

    Transformer tractography model for mouse-brain diffusion MRI, guided by axonal priors learned from Allen Mouse Brain Connectivity Atlas streamlines.

    Imaging
    8Openness
  • RegVelo

    17519
    Helmholtz MunichMay 11, 2026chromatingene_regulatory_network_inferencegenerative+4

    Bayesian generative model that embeds gene regulatory networks into RNA velocity inference, enabling cell fate mapping and in silico perturbation.

    Single-cell
    59Openness
  • PTM-dCN

    53
    Shanghai Jiao Tong UniversityMay 11, 2026de_novo_designdiffusiongenerative+3

    Latent diffusion model for PTM-aware protein sequence design, using ControlNet-style conditioning to steer generation toward chosen PTM sites.

    Protein
    10Openness
  • University of ZurichMay 11, 2026denoisingmetagenomicsmicrobiome+4

    Microbiome world model that treats a community as a set of taxa, scoring how well each member fits and predicting community dynamics zero-shot.

    DNA & Gene
    48Openness
  • BRIDGE

    The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8

    Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.

    PathologySpatial omics
    31Openness
  • GoForth

    232
    University of California, BerkeleyMay 8, 2026encoder_decodergenerativeinverse_folding+5

    RNA inverse-folding language model that designs nucleotide sequences satisfying a target secondary structure, fixed bases, and coding constraints.

    RNA
    63Openness
  • ConvergeCELL

    17
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    Virtual cell foundation model pretrained on over 23 million cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • MochiDiff

    University of Washington +1 otherMay 7, 2026antibodyantibody_designde_novo_design+6

    Discrete diffusion model for conditional antibody sequence design with germline-absorbing noising that focuses learning on somatic variation.

    Protein
    8Openness
  • ProtSent

    6
    Hebrew University of Jerusalem +1 otherMay 7, 2026contrastive_learningembeddingsproteomics+4

    Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.

    Protein
    87Openness
  • Wisteria

    8
    Inner Mongolia UniversityMay 7, 2026cnndnafoundation_model+6

    DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier attention to capture multi-scale regulatory patterns.

    DNA & Gene
    10Openness
  • Waypoint

    29
    Outpost BioMay 6, 2026foundation_modelgptmetagenomics+5

    Microbiome foundation models that treat microbial community composition as a language, enabling zero- and few-shot transfer across prediction tasks.

    DNA & Gene
    23Openness
  • A-CODE

    University of Illinois Urbana-Champaign +1 otherMay 5, 2026binder_designde_novo_designdiffusion+4

    All-atom protein co-design model that generates sequence and structure together in one unified diffusion process, aimed at hard binder design.

    Protein
    8Openness
  • University of Naples Federico II +1 otherMay 5, 2026de_novo_designgenerativeprotein_design+2

    Three fixed ProtGPT2 fine-tunes specialized for metalloprotein generation, trained on ProteinMPNN-derived synthetic sequences.

    Protein
    38Openness