All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 97106 of 106 filtered models

  • CELL-Diff

    7
    Chan Zuckerberg InitiativeOctober 18, 2024cell_biologyde_novo_designdiffusion+7

    Diffusion model translating in both directions between protein sequences and fluorescence microscopy images to predict subcellular localization.

    Imaging
    87Openness
  • Chai-1

    2K403
    Chai DiscoveryOctober 11, 2024diffusiondrug_discoveryfoundation_model+2

    Biomolecular structure prediction foundation model covering proteins, small molecules, DNA, RNA, and glycans in a single diffusion framework.

    Protein
    49Openness
  • DFMDock

    557
    Johns Hopkins UniversitySeptember 27, 2024contrastive_learningdiffusiongenerative+3

    Diffusion model for protein-protein docking that unifies pose sampling and energy-based ranking, works without MSAs, and generalizes to new targets.

    Protein
    81Openness
  • HelixFold3

    1.1K38
    Baidu PaddleHelixAugust 30, 2024biomoleculardiffusionstructure_prediction

    Open-source reproduction of AlphaFold 3 that predicts structures of proteins, DNA, RNA, and small-molecule ligands, including their mixed complexes.

    Protein
    14Openness
  • Microsoft ResearchMay 13, 2024cryo_emdiffusiondrug_discovery+8

    Deep learning framework predicting equilibrium distributions of molecular systems, enabling efficient ensemble generation and conformation sampling.

    Protein
    46Openness
  • Prescient Design +1 otherMay 7, 2024antibodyantibody_designde_novo_design+4

    Discrete generative model for antibody protein sequences combining MCMC walks on a smoothed energy landscape with one-step denoising jumps.

    Protein
    60Openness
  • Tsinghua UniversityJanuary 1, 2024diffusionfoundation_modelgenerative

    Diffusion model for synthesizing single-cell RNA-seq data, with guided generation of specific cell types, rare cells, and developmental trajectories.

    Single-cell
    60Openness
  • Chroma

    824
    Generate:BiomedicinesNovember 1, 2023diffusiongenerativegraph_neural_network+3

    Diffusion model for programmable protein design that jointly samples structures and sequences, conditioned on symmetry, shape, or text prompts.

    Protein
    53Openness
  • EvoDiff

    675226
    Microsoft ResearchSeptember 12, 2023cnnde_novo_designdiffusion+8

    Discrete diffusion model for protein sequence and MSA generation, enabling controllable de novo design directly in sequence space without structure.

    Protein
    84Openness
  • RFdiffusion

    3K1.3K
    Institute for Protein DesignJuly 11, 2023de_novo_designdiffusionmotif_scaffolding+2

    De novo protein design diffusion model that generates backbone structures conditioned on binding targets, symmetry constraints, and functional motifs.

    Protein
    60Openness