Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1153–1176 of 2336 models
Kinase-substrate specificity prediction from sequence alone, using ESM-2 embeddings to score phosphorylation across whole mammalian kinomes.
Multimodal physiological foundation model spanning EEG, ECG, EOG, and EMG that keeps working when arbitrary modalities are missing at inference time.
Single-cell foundation model inferring context-specific protein-protein interactions from cancer transcriptomes via a variational graph autoencoder.
Single-cell type annotation pairing a CellMarker-derived knowledge graph with multi-agent LLM retrieval, generalizing across 11 tissue types.
Structure-aware protein language model aligning sequence and 3D structure by contrastive learning, with adapter and LoRA fine-tuning tools.
Cryptic protein binding site prediction from sequence, backed by a database of 5,151 cryptic sites mined from 6 million apo-holo PDB alignments.
Multi-resolution vision-language foundation model for histopathology, pretrained on 34M TCGA image-text pairs across four magnifications.
Spatial transcriptomics prediction from H&E whole-slide images. One generative checkpoint covers 38,984 genes and 17 organs without fine-tuning.
Linear B-cell epitope prediction using phylogeny-aware fine-tuning of ESM embedders, with taxon-specific models for 19 pathogen groups.
CRISPR/Cas9 off-target prediction that fine-tunes a DNA language model and gates in chromatin signal, reaching 0.550 PR-AUC on GUIDE-seq data.
Single-cell foundation model contrastively fine-tuned on genome-scale Perturb-seq data to separate perturbed from unperturbed transcriptomic states.
Single-cell foundation model built on bidirectional Mamba blocks and pretrained on 30 million cells for linear-time transcriptome embedding.
TCR-peptide binding prediction that fuses ESM-1b receptor embeddings with MolFormer SMILES embeddings through multi-head cross-attention.
Protein binding affinity prediction from sequence alone, returning pKd and per-residue interface labels instead of a yes-or-no interaction call.
Per-residue pKa prediction from sequence alone, a thin MLP head on frozen ESM-2 embeddings reaching 0.48 RMSE across six titratable residue types.
Per-residue pKa prediction from sequence alone, a thin MLP head on frozen ESM Cambrian embeddings that holds up better on engineered buried variants.
Unified electron microscopy image analysis toolkit built on EM-DINO, a vision foundation model pretrained on 5 million diverse EM images.
Topology-guided protein backbone generation that turns hand-drawn 3D curves into designable structures by steering a diffusion sampler with a sketch.
Whole-genome bacterial pathogenicity prediction from ProtT5 embeddings, alignment-free and taxonomy-agnostic, with per-protein attention scores.