All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 7396 of 203 filtered models

  • CaltechFebruary 6, 2026autoencoderprotein_designprotein_structure+4

    Protein structure tokenizer that encodes a whole structure globally, with each successive token adding detail for adaptive-length representations.

    Protein
    6Openness
  • TM-Vec 2

    1
    Arizona State UniversityFebruary 5, 2026embeddingshomology_detectionproteomics+3

    Protein structural homology search from sequence alone, embedding proteins so that structural similarity becomes a fast nearest-neighbor lookup.

    Protein
    4Openness
  • Helmholtz MunichFebruary 5, 2026frustration_predictionintrinsically_disordered_regionsprotein_function_annotation+4

    Protein language model that predicts per-residue local energetic frustration directly from sequence, covering whole proteomes and disordered regions.

    Protein
    78Openness
  • evoRate

    University of TorontoFebruary 2, 2026genomicsmolecular_evolutionregulatory_genomics+4

    Genome language model that adds evolutionary-rate prediction to pretraining, improving representations for variant effect and regulatory genomics.

    DNA & Gene
    14Openness
  • CHASE

    ETH Zurich +1 otherFebruary 2, 2026autoencoderdirected_evolutionfitness_optimization+4

    Latent flow-matching method that repurposes protein language model embeddings to generate high-fitness protein variants without predictor guidance.

    Protein
    11Openness
  • COSMIC

    EPFLJanuary 24, 2026autoencodercell_biologycell_type_annotation+7

    Bidirectional generative framework linking nuclear morphology and gene expression, built on a morphology model trained on 21 million segmented nuclei.

    ImagingSingle-cellSpatial omics
    4Openness
  • FoldVision

    Heinrich Heine University DüsseldorfJanuary 23, 2026cnndrug_discoveryenzymes+5

    Structure-based protein encoder that voxelizes every heavy atom into a 3D grid, learning orientation-robust representations for protein function.

    Protein
    20Openness
  • SAGE-FM

    Stanford UniversityJanuary 21, 2026cell_type_annotationfoundation_modelgene_expression+4

    Spatial transcriptomics foundation model built on a lightweight graph convolutional network and trained by masked central-spot prediction.

    Spatial omicsSingle-cell
    10Openness
  • PepEDiff

    2
    University of CincinnatiJanuary 19, 2026de_novo_designdiffusiongenerative+6

    Zero-shot peptide binder designer that runs diffusion in a pretrained protein embedding space, proposing binders without structure prediction.

    Protein
    62Openness
  • GluFormer

    8719
    Weizmann Institute of Science +2 othersJanuary 14, 2026continuous_glucose_monitoringfoundation_modelgenerative+6

    Generative transformer foundation model for continuous glucose monitoring, forecasting glycemia and stratifying health risk from raw glucose traces.

    Biosignals
    60Openness
  • Macao Polytechnic UniversityJanuary 12, 2026de_novo_designdiffusiongenerative+6

    Sequence-only latent diffusion model that designs target-specific peptide binders, cascaded with an affinity classifier through joint optimization.

    ProteinSmall molecule
    4Openness
  • BiomeGPT

    1
    Massachusetts General HospitalJanuary 5, 2026biomarker_discoverydisease_classificationfoundation_model+6

    Gut microbiome foundation model pretrained on human shotgun metagenomes, learning species-level taxonomic representations for disease prediction.

    DNA & GeneLanguage model
    8Openness
  • MetagenBERT

    MetagenBERT AuthorsJanuary 5, 2026bertdnaembeddings+5

    Annotation-free metagenome embedding pipeline that encodes raw DNA reads with genomic language models and pools them via FAISS k-means clustering.

    DNA & Gene
    22Openness
  • Nobuyuki OtaJanuary 3, 2026cell_biologygene_expressiongenomics+4

    Multimodal architecture coupling pretrained DNA, RNA, and protein language models with directional cross-attention into one Virtual Cell Embedding.

    DNA & GeneRNAProtein
    22Openness
  • Harvard Medical SchoolDecember 31, 2025cell_biologyfoundation_modelmicroscopy+5

    Native 3D vision transformer self-supervised on unlabeled fluorescence microscopy volumes, segmenting subcellular structures without voxel labels.

    Imaging
    8Openness
  • MicroGenomer

    10
    BGI ResearchDecember 29, 2025embeddingsfoundation_modelgenomics+6

    470M-parameter microbial genome foundation model trained on 234.5B base pairs for multi-scale genomic representation and trait prediction.

    DNA & Gene
    44Openness
  • HELM-BERT

    14471
    Kyoto UniversityDecember 29, 2025debertalanguage_modelmacrocycles+7

    Peptide language model trained on HELM notation, a DeBERTa encoder for property prediction on macrocyclic and non-canonical medium-sized peptides.

    Small molecule
    80Openness
  • GlycanGT

    3
    Nagoya UniversityDecember 16, 2025foundation_modelglycobiologyglycomics+5

    Graph transformer foundation model for glycans, learning reusable embeddings of branched carbohydrate structures for glycomics prediction tasks.

    Small molecule
    82Openness
  • cfRNA-ICL

    Eigen BioDecember 13, 2025cancer_classificationcell_free_rnaearly_cancer_detection+7

    In-context learning model for cell-free RNA, meta-trained on synthetic tasks from a cfRNA structural causal model for few-shot cancer classification.

    Single-cellRNA
    8Openness
  • ISTS

    New York UniversityDecember 2, 2025autoencoderbertcancer_classification+9

    Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.

    Single-cellDNA & Gene
    20Openness
  • CLEF

    554
    Nokia Bell LabsDecember 1, 2025cardiovascular_risk_predictioncnncontrastive_learning+5

    Single-lead ECG foundation model pretrained on 12-lead recordings, weighting contrastive pairs by clinical risk for cardiovascular risk prediction.

    Biosignals
    62Openness
  • TEA

    2443.7K
    Biozentrum +2 othersNovember 27, 2025contrastive_learninghomology_detectionproteomics+4

    Protein sequence encoder that maps ESM2 embeddings to a learned 20-letter alphabet for structure-quality remote homology detection at MMseqs2 speed.

    Protein
    86Openness
  • PULSAR

    364166
    Stanford UniversityNovember 26, 2025biomarker_predictiondisease_classificationfoundation_model+6

    Hierarchical single-cell foundation model that turns scRNA-seq profiles into zero-shot donor-level embeddings for disease and biomarker prediction.

    Single-cellProtein
    58Openness
  • Technion – Israel Institute of Technology +1 otherNovember 26, 2025function_predictiongraph_neural_networkmultimodal+4

    Multimodal protein representation model that iteratively fuses a sequence language model with a 3D structure encoder through a shared learnable token.

    Protein
    68Openness