All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 4972 of 158 filtered models

  • CLIPepPI

    2
    Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5

    Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.

    Protein
    50Openness
  • AI-IDP

    German Center for Neurodegenerative Diseases (DZNE)March 16, 2026conformational_ensemble_generationintrinsically_disordered_proteinsproteomics+3

    Sequence-to-ensemble predictor that generates conformational ensembles of intrinsically disordered proteins zero-shot, with no per-sequence refitting.

    Protein
    4Openness
  • ATOMICA

    3
    Harvard UniversityMarch 16, 2026binding_site_predictionfoundation_modelgraph_neural_network+6

    Geometric deep learning model that learns atomic-scale representations of molecular interfaces across proteins, small molecules, and nucleic acids.

    ProteinSmall moleculeRNA
    88Openness
  • HitAnno

    Tsinghua UniversityMarch 10, 2026cell_type_annotationchromatin_accessibilitylanguage_model+4

    Hierarchical language model for atlas-level cell-type annotation of scATAC-seq data that annotates new query datasets without retraining.

    Single-cell
    14Openness
  • Popformer

    University of PennsylvaniaMarch 6, 2026foundation_modelgenomicspopulation_genetics+6

    Self-supervised transformer for population genetics, pretrained on 1000 Genomes data, that detects positive selection via haplotype-wise attention.

    DNA & Gene
    19Openness
  • VirtualCRISPR

    Chan Zuckerberg Biohub Chicago +2 othersFebruary 28, 2026crisprdrug_discoveryfoundation_model+2

    Large language model trained on functional genomics data to prioritize novel therapeutic targets from genome-wide CRISPR knockout screens.

    DNA & GeneLanguage model
    12Openness
  • OncoBERT

    National Cancer InstituteFebruary 19, 2026bertlanguage_modeloncology+7

    BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.

    DNA & Gene
    7Openness
  • Columbia UniversityFebruary 17, 2026dna_methylationepigenomicsfoundation_model+4

    Transformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.

    DNA & Gene
    10Openness
  • evoCancerGPT

    Dana-Farber Cancer InstituteFebruary 14, 2026cancerfoundation_modelgene_expression+5

    Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.

    Single-cell
    11Openness
  • Tsinghua UniversityFebruary 14, 2026autoregressivecell_biologyde_novo_design+7

    Protein language model that encodes sequences as discrete words from a learned vocabulary for zero-shot function inference and protein design.

    Protein
    24Openness
  • STPAINTER

    University of Science and Technology of China +2 othersFebruary 13, 2026cancerdiffusionfoundation_model+4

    Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.

    Spatial omicsSingle-cell
    4Openness
  • DERIVE

    Guangzhou National LaboratoryFebruary 12, 2026flow_matchingfoundation_modelgenerative+5

    Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.

    Protein
    16Openness
  • dnaHNet

    2
    Arc Institute +2 othersFebruary 11, 2026dnafoundation_modelgene_essentiality_prediction+7

    Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.

    DNA & Gene
    12Openness
  • BioCLIP 2.5

    77435.3K
    Imageomics InstituteFebruary 10, 2026biodiversitycontrastive_learningfoundation_model+6

    Vision foundation model for the tree of life, scaling BioCLIP 2 to a ViT-H/14 backbone and more organism images for zero-shot species classification.

    Imaging
    93Openness
  • EVA

    89
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.

    Single-cellRNAPathology
    27Openness
  • ARSENAL

    16
    Stanford UniversityFebruary 6, 2026chromatinlanguage_modelmotif_discovery+6

    Masked DNA language model for regulatory genomics with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.

    DNA & Gene
    29Openness
  • CaltechFebruary 6, 2026autoencoderprotein_designprotein_structure+4

    Protein structure tokenizer that encodes a whole structure globally, with each successive token adding detail for adaptive-length representations.

    Protein
    6Openness
  • AdarEdit

    3
    Stanford University +1 otherFebruary 4, 2026a_to_i_editingcnngraph_attention_network+5

    Graph-attention model that predicts A-to-I RNA editing from sequence and secondary structure, treating RNA as a graph with base-pairing edges.

    RNA
    79Openness
  • MoLF

    National Center for Tumor Diseases DresdenFebruary 2, 2026flow_matchinggene_expressiongenerative+5

    Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.

    PathologySpatial omics
    9Openness
  • Proust

    9
    ETH ZurichFebruary 2, 2026foundation_modellanguage_modelprotein_design+3

    Causal 309M-parameter protein language model that scores variant fitness zero-shot and generates sequences, reaching 0.390 Spearman on ProteinGym.

    Protein
    9Openness
  • Beijing Zhongguancun Academy +4 othersJanuary 29, 2026autoregressivednafoundation_model+6

    Family of autoregressive genomic foundation models that reconcile k-mer tokenization with single-nucleotide resolution at contexts up to 98k bp.

    DNA & Gene
    86Openness
  • TwinCell

    2
    DeepLifeJanuary 29, 2026cancerfoundation_modelgene_regulation+4

    Large causal cell model trained on cancer perturbation data that generalizes zero-shot to patient-derived cells for therapeutic target prioritization.

    Single-cell
    19Openness
  • PepEDiff

    2
    University of CincinnatiJanuary 19, 2026de_novo_designdiffusiongenerative+6

    Zero-shot peptide binder designer that runs diffusion in a pretrained protein embedding space, proposing binders without structure prediction.

    Protein
    62Openness
  • ConGLUDe

    Johannes Kepler University LinzJanuary 14, 2026binding_site_predictioncontrastive_learningdrug_discovery+7

    Contrastive geometric model unifying structure- and ligand-based drug design for zero-shot virtual screening, target fishing, and pocket selection.

    ProteinSmall molecule
    8Openness