All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 49–72 of 158 filtered models
CLIPepPI
2——Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.
Protein50OpennessAI-IDP
———German Center for Neurodegenerative Diseases (DZNE)March 16, 2026conformational_ensemble_generationintrinsically_disordered_proteinsproteomics+3Sequence-to-ensemble predictor that generates conformational ensembles of intrinsically disordered proteins zero-shot, with no per-sequence refitting.
Protein4OpennessATOMICA
—3—Geometric deep learning model that learns atomic-scale representations of molecular interfaces across proteins, small molecules, and nucleic acids.
ProteinSmall moleculeRNA88OpennessHitAnno
———Hierarchical language model for atlas-level cell-type annotation of scATAC-seq data that annotates new query datasets without retraining.
Single-cell14OpennessPopformer
———Self-supervised transformer for population genetics, pretrained on 1000 Genomes data, that detects positive selection via haplotype-wise attention.
DNA & Gene19OpennessLarge language model trained on functional genomics data to prioritize novel therapeutic targets from genome-wide CRISPR knockout screens.
DNA & GeneLanguage model12OpennessOncoBERT
———BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.
DNA & Gene7OpennessTransformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.
DNA & Gene10OpennessevoCancerGPT
———Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.
Single-cell11OpennessProtein language model that encodes sequences as discrete words from a learned vocabulary for zero-shot function inference and protein design.
Protein24OpennessSTPAINTER
———University of Science and Technology of China +2 othersFebruary 13, 2026cancerdiffusionfoundation_model+4Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.
Spatial omicsSingle-cell4OpennessDERIVE
———Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.
Protein16OpennessdnaHNet
—2—Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.
DNA & Gene12OpennessBioCLIP 2.5
77435.3KVision foundation model for the tree of life, scaling BioCLIP 2 to a ViT-H/14 backbone and more organism images for zero-shot species classification.
Imaging93OpennessEVA
——89Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessARSENAL
16——Masked DNA language model for regulatory genomics with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.
DNA & Gene29OpennessProtein structure tokenizer that encodes a whole structure globally, with each successive token adding detail for adaptive-length representations.
Protein6OpennessAdarEdit
3——Graph-attention model that predicts A-to-I RNA editing from sequence and secondary structure, treating RNA as a graph with base-pairing edges.
RNA79OpennessMoLF
———Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.
PathologySpatial omics9OpennessProust
9——Causal 309M-parameter protein language model that scores variant fitness zero-shot and generates sequences, reaching 0.390 Spearman on ProteinGym.
Protein9OpennessGENERator-v2
4601—Family of autoregressive genomic foundation models that reconcile k-mer tokenization with single-nucleotide resolution at contexts up to 98k bp.
DNA & Gene86OpennessPepEDiff
2——Zero-shot peptide binder designer that runs diffusion in a pretrained protein embedding space, proposing binders without structure prediction.
Protein62OpennessConGLUDe
———Johannes Kepler University LinzJanuary 14, 2026binding_site_predictioncontrastive_learningdrug_discovery+7Contrastive geometric model unifying structure- and ligand-based drug design for zero-shot virtual screening, target fishing, and pocket selection.
ProteinSmall molecule8Openness