All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 4972 of 518 filtered models

  • PepForge

    4
    Technical University of BerlinJune 2, 2026antimicrobial_peptidesbertde_novo_design+7

    Generative model for chemically modified and macrocyclic peptides that builds molecules in HELM notation, supporting de novo design and infilling.

    ProteinSmall molecule
    94Openness
  • TARIO-2

    NoetikJune 1, 2026foundation_modelgene_expressionhistology+4

    Tumor foundation model that infers whole-transcriptome and microenvironment signal from H&E slides, pretrained on paired spatial transcriptomics.

    PathologySpatial omics
    6Openness
  • CryoProt

    Hunan University +1 otherJune 1, 2026active_site_identificationbinding_affinitycryo_em+7

    Protein representation learning from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.

    ImagingProtein
    11Openness
  • TESSERA

    5
    Weill Cornell MedicineJune 1, 2026cancer_genomicscell_type_annotationcontrastive_learning+5

    Self-supervised foundation model that embeds cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types for tumor subtyping.

    DNA & Gene
    28Openness
  • Vermeer

    3
    Microsoft Research +2 othersJune 1, 2026autoregressivecell_biologyfluorescence_microscopy+7

    Generative microscopy foundation model that synthesizes in-silico fluorescence images of protein subcellular localization from amino-acid sequence.

    ImagingProtein
    17Openness
  • mRNAutilus

    1
    Atom Bioworks +3 othersMay 31, 2026de_novo_designdiffusionfoundation_model+5

    Masked discrete-diffusion model over millions of full-length mRNAs, steered by Monte Carlo tree search for joint codon optimization and UTR design.

    RNA
    7Openness
  • TxFM

    2
    Recursion PharmaceuticalsMay 31, 2026autoencoderfoundation_modelgene_expression+4

    Transcriptomics foundation model from Recursion that masks and reconstructs RNA-seq gene expression counts to learn reusable sample embeddings.

    Single-cell
    12Openness
  • Nanjing University +2 othersMay 30, 2026foundation_modelgene_expression_predictionhistology+5

    Tri-modal foundation model unifying histology images, spatial transcriptomics, and language for zero-shot pathology and spatial biology reasoning.

    PathologySpatial omics
    65Openness
  • GlucoFM

    2
    Google Research +1 otherMay 29, 2026continuous_glucose_monitoringfoundation_modelglucose_forecasting+4

    Self-supervised foundation model for continuous glucose monitoring, with dual streams separating slow physiological state from transient events.

    Biosignals
    11Openness
  • DanioDecima

    Biohub +1 otherMay 29, 2026cnnde_novo_designdna+7

    Zebrafish sequence-to-function model predicting cell-type-specific gene expression from DNA sequence across embryonic development.

    DNA & GeneSingle-cell
    22Openness
  • ESMC

    2.9K102.1M
    BiohubMay 27, 2026foundation_modelmasked_language_modelingprotein_design+6

    Protein language model trained on roughly 2.8 billion sequences, forming the representation core of Biohub's world model of protein biology.

    Protein
    63Openness
  • ESMFold2

    2.9K10320.4K
    BiohubMay 27, 2026antibodybinder_designbiomolecular_complex+5

    Structure-prediction and design engine that turns ESMC sequence representations into all-atom 3D structures of proteins and biomolecular complexes.

    Protein
    61Openness
  • LucaPhylo

    13
    Alibaba Cloud +2 othersMay 26, 2026few_shotlanguage_modelphylogenetic_inference+5

    Hyperbolic protein language model for alignment-free phylogenetic inference, turning ESM2-650M embeddings into distance matrices for tree placement.

    Protein
    86Openness
  • OryzaG3

    Hainan UniversityMay 26, 2026causal_language_modeldnagenomic_variant_prediction+8

    700M-parameter DNA language model pretrained on the rice pangenome, serving as a reusable base model for crop genomics and molecular breeding.

    DNA & Gene
    19Openness
  • C3P

    1
    University of TorontoMay 24, 2026bacterial_genomeco_regulated_gene_retrievalcontrastive_learning+8

    Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.

    DNA & Gene
    77Openness
  • D2D

    1
    Vrije Universiteit Brussel +1 otherMay 22, 2026binding_region_predictionepistasisintrinsically_disordered_regions+5

    Variant effect predictor pairing a protein language model with family-specific evolutionary constraints to score stability, binding, and epistasis.

    Protein
    29Openness
  • Griffith University +2 othersMay 21, 2026flow_matchinggenerative_modelprotein_design+5

    Dirichlet flow-matching model for protein design that generates family-aware sequences from ancestral-reconstruction priors, not random noise.

    Protein
    64Openness
  • Genos-m

    26123
    BGI-HangzhouAIMay 21, 2026foundation_modelgene_fitness_predictionmetagenomics+7

    Mixture-of-Experts genomic foundation model for the human microbiome, with 4.7B parameters pretrained on bacterial, archaeal, and phage genomes.

    DNA & Gene
    73Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.

    RNA
    11Openness
  • Albatross

    Harvard Medical SchoolMay 20, 2026ireslanguage_modelsecondary_structure_prediction+4

    RNA language model that predicts secondary structure of internal ribosome entry sites from sequence alone, trained on roughly 50,000 IRES sequences.

    RNA
    15Openness
  • TMEformer

    Sichuan UniversityMay 20, 2026cancerfoundation_modelin_silico_perturbation+6

    Spatial transcriptomics foundation model for the tumor microenvironment, giving TME-aware embeddings and in silico perturbation from one checkpoint.

    Spatial omics
    10Openness
  • MetFoundation

    Hong Kong Baptist UniversityMay 20, 2026aging_clockcontrastive_learningdisease_risk_prediction+6

    Metabolomic foundation model pretrained on UK Biobank NMR metabolite profiles, reused with a frozen backbone for aging, subtyping, and disease risk.

    Metabolomics
    7Openness
  • PlasmidLM

    2
    University College LondonMay 19, 2026dnalanguage_modelplasmid_design+4

    Promptable DNA language model that generates multi-kilobase plasmid sequences from plain-language component specs, refined with verifiable rewards.

    DNA & Gene
    49Openness
  • University of FloridaMay 18, 2026bertbilstmcnn+11

    Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.

    DNA & Gene
    45Openness