All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 203 filtered models

  • FlowTransOP

    MIT +2 othersMay 27, 2026autoencodercross_domain_translationcross_species+7

    Flow-matching framework that translates omics signatures across biological domains, such as mouse to human transcriptomics, without paired samples.

    Single-cell
    87Openness
  • LucaPhylo

    13
    Alibaba Cloud +2 othersMay 26, 2026few_shotlanguage_modelphylogenetic_inference+5

    Hyperbolic protein language model for alignment-free phylogenetic inference, turning ESM2-650M embeddings into distance matrices for tree placement.

    Protein
    86Openness
  • TMEformer

    Sichuan UniversityMay 20, 2026cancerfoundation_modelin_silico_perturbation+6

    Spatial transcriptomics foundation model for the tumor microenvironment, giving TME-aware embeddings and in silico perturbation from one checkpoint.

    Spatial omics
    10Openness
  • ETH ZurichMay 18, 2026autoencoderfold_classificationfoundation_model+5

    SE(3)-invariant masked autoencoder that learns protein fold representations from AlphaFold-DB structures, supporting zero-shot fold classification.

    Protein
    78Openness
  • PLM-SAE

    Shanghai Smart Logic Technology Co., Ltd.May 15, 2026autoencoderproteomicsrepresentation_learning+3

    Sparse autoencoders trained on protein language model embeddings to expose interpretable features and drive zero-shot variant effect prediction.

    Protein
    22Openness
  • ENSEMBITS

    7
    Vanderbilt UniversityMay 13, 2026function_predictionmolecular_dynamicsprotein_dynamics+5

    Protein conformational ensemble tokenizer that learns a discrete alphabet of states from molecular dynamics, reusable as a frozen feature layer.

    Protein
    66Openness
  • Susagi

    84
    University of ZurichMay 11, 2026denoisingmetagenomicsmicrobiome+4

    Microbiome world model that treats a community as a set of taxa, scoring how well each member fits and predicting community dynamics zero-shot.

    DNA & Gene
    48Openness
  • BRIDGE

    The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8

    Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.

    PathologySpatial omics
    31Openness
  • ProtSent

    712
    Hebrew University of Jerusalem +1 otherMay 7, 2026contrastive_learningembeddingsproteomics+4

    Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.

    Protein
    87Openness
  • Waypoint

    Outpost BioMay 6, 2026foundation_modelgptmetagenomics+5

    Microbiome foundation models that treat microbial community composition as a language, enabling zero- and few-shot transfer across prediction tasks.

    DNA & Gene
    23Openness
  • Emory University +2 othersApril 30, 2026brain_age_estimationdisease_classificationfoundation_model+6

    Self-supervised brain MRI foundation model built on DINOv3, pretrained on roughly 6.6 million unlabeled axial slices for neuroimaging tasks.

    Imaging
    49Openness
  • University of Texas at Austin +1 otherApril 17, 2026bertdrug_discoveryfoundation_model+7

    Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.

    Small moleculeProtein
    79Openness
  • DIA-CLIP

    AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6

    Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.

    Protein
    11Openness
  • xVERSE

    Duke UniversityApril 14, 2026batch_effect_correctionfoundation_modelgenerative+5

    Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.

    Single-cell
    10Openness
  • GenoJEPA

    Beijing University of Posts and TelecommunicationsApril 6, 2026foundation_modelgenomicsrepresentation_learning+4

    Genomic foundation model that learns DNA representations by predicting masked regions in latent space rather than reconstructing raw nucleotides.

    DNA & Gene
    22Openness
  • STORM

    3
    Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6

    Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.

    Spatial omicsPathology
    17Openness
  • GATSBI

    13
    Stanford UniversityApril 3, 2026embeddingsfunction_predictiongraph_attention_network+4

    Graph attention model that learns context-aware protein embeddings from protein-protein interaction, co-expression, and tissue association networks.

    Protein
    94Openness
  • muat

    8
    University of HelsinkiApril 3, 2026attentioncancer_genomicsrepresentation_learning+5

    Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.

    DNA & Gene
    65Openness
  • Cold Spring Harbor LaboratoryApril 1, 2026de_novo_designdiffusiongene_expression+5

    Discrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.

    DNA & Gene
    49Openness
  • ZeroFold

    University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3

    Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.

    RNAProtein
    23Openness
  • genbio.aiMarch 20, 2026foundation_modelhistologyrepresentation_learning+3

    Histopathology foundation model with 1.1B parameters, trained entirely on public data using JEDI, a dual-stage strategy combining JEPA and DINO.

    Pathology
    21Openness
  • RNAGAN

    1
    The University of Hong KongMarch 20, 2026cancercell_type_annotationdata_generation+5

    Generative adversarial network trained on single-cell and bulk RNA-seq for sample stratification, marker analysis, and synthetic data generation.

    Single-cell
    60Openness
  • ProteinSage

    BioMapMarch 19, 2026foundation_modelprotein_structurerepresentation_learning+3

    Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.

    Protein
    12Openness
  • Horizyn-1

    123
    Dayhoff LabsMarch 17, 2026contrastive_learningenzyme_reaction_matchingenzymology+5

    Dual-encoder contrastive model that retrieves enzymes for query reactions by matching reaction fingerprints to protein sequence embeddings.

    ProteinSmall molecule
    21Openness