All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 203 filtered models
FlowTransOP
———Flow-matching framework that translates omics signatures across biological domains, such as mouse to human transcriptomics, without paired samples.
Single-cell87OpennessLucaPhylo
13——Hyperbolic protein language model for alignment-free phylogenetic inference, turning ESM2-650M embeddings into distance matrices for tree placement.
Protein86OpennessTMEformer
———Spatial transcriptomics foundation model for the tumor microenvironment, giving TME-aware embeddings and in silico perturbation from one checkpoint.
Spatial omics10OpennessSE(3)-invariant masked autoencoder that learns protein fold representations from AlphaFold-DB structures, supporting zero-shot fold classification.
Protein78OpennessPLM-SAE
———Sparse autoencoders trained on protein language model embeddings to expose interpretable features and drive zero-shot variant effect prediction.
Protein22OpennessENSEMBITS
7——Protein conformational ensemble tokenizer that learns a discrete alphabet of states from molecular dynamics, reusable as a frozen feature layer.
Protein66OpennessSusagi
8—4Microbiome world model that treats a community as a set of taxa, scoring how well each member fits and predicting community dynamics zero-shot.
DNA & Gene48OpennessBRIDGE
———The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.
PathologySpatial omics31OpennessProtSent
7—12Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.
Protein87OpennessWaypoint
———Microbiome foundation models that treat microbial community composition as a language, enabling zero- and few-shot transfer across prediction tasks.
DNA & Gene23OpennessBrainDINO
53—Emory University +2 othersApril 30, 2026brain_age_estimationdisease_classificationfoundation_model+6Self-supervised brain MRI foundation model built on DINOv3, pretrained on roughly 6.6 million unlabeled axial slices for neuroimaging tasks.
Imaging49OpennessPeptideCLM-2
102—Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.
Small moleculeProtein79OpennessDIA-CLIP
———AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.
Protein11OpennessxVERSE
———Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.
Single-cell10OpennessGenoJEPA
———Beijing University of Posts and TelecommunicationsApril 6, 2026foundation_modelgenomicsrepresentation_learning+4Genomic foundation model that learns DNA representations by predicting masked regions in latent space rather than reconstructing raw nucleotides.
DNA & Gene22OpennessSTORM
—3—Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.
Spatial omicsPathology17OpennessGATSBI
13——Graph attention model that learns context-aware protein embeddings from protein-protein interaction, co-expression, and tissue association networks.
Protein94Opennessmuat
8——Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.
DNA & Gene65OpennessDiscrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.
DNA & Gene49OpennessZeroFold
———University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.
RNAProtein23OpennessGenBio-PathFM
372714Histopathology foundation model with 1.1B parameters, trained entirely on public data using JEDI, a dual-stage strategy combining JEPA and DINO.
Pathology21OpennessRNAGAN
1——Generative adversarial network trained on single-cell and bulk RNA-seq for sample stratification, marker analysis, and synthetic data generation.
Single-cell60OpennessProteinSage
———Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.
Protein12OpennessHorizyn-1
123—Dual-encoder contrastive model that retrieves enzymes for query reactions by matching reaction fingerprints to protein sequence embeddings.
ProteinSmall molecule21Openness