All Competitors

VHH nanobody expression predictor needing only an amino-acid sequence, no structure. Leave-program-out ROC-AUC 0.81 on unseen antibody programs.

Peptide developability predictor scoring solubility, permeability, toxicity, and binding from amino-acid sequences or chemically modified SMILES.

Protein-protein binding affinity prediction from sequence alone, pairing frozen protein language model embeddings with gradient-boosted trees.

Peptide-MHC class I binding predictor that scores force-field energy terms from modeled pMHC structures, holding precision on rare HLA alleles.

Splicing variant effect prediction across 49 human tissues and 15 developmental stages, from four weeks post conception to adulthood.

Deep mutational scanning score imputation across protein domains, pairing ESM-1v embeddings with EVE conservation and physicochemical features.

Enzyme kcat and KM prediction from sequence and substrate SMILES, binned by order of magnitude so catalytic-site mutations shift the prediction.

Anti-phage defense gene classifier pairing protein language model embeddings with genomic features to find immune systems outside defense islands.

Transcription factor binding site prediction in regulatory DNA from accessibility, motifs and TF expression. One fixed model covers unseen factors.

Spatial proteomics imputation from a 7-plex immunofluorescence panel, generating in silico CODEX expression for 33 more biomarkers per cell.