All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 169192 of 518 filtered models

  • CALM-1.0

    3
    ETH ZurichFebruary 26, 2026antibodyantibody_designantigen+6

    Contrastive antibody language model predicting antibody-antigen binding specificity from sequence with a dual-encoder, cross-attentive architecture.

    Protein
    10Openness
  • CellPace

    McGill UniversityFebruary 26, 2026cell_biologydiffusiongene_expression+5

    Temporal diffusion framework for single-cell developmental dynamics, interpolating and forecasting cell states from irregularly sampled time series.

    Single-cell
    9Openness
  • ESMRank

    TIGEMFebruary 26, 2026deep_mutational_scanningproteomicsrepresentation_learning+3

    Learning-to-rank variant effect predictor that aligns overlapping deep mutational scanning assays into an assay-agnostic tolerance measure.

    Protein
    10Openness
  • ARCH3D

    University of MichiganFebruary 25, 20263d_genomechromatincontact_map_reconstruction+5

    Foundation model for 3D genome architecture, using masked locus modeling over genome-wide contact profiles to capture chromosome-scale organization.

    DNA & Gene
    19Openness
  • ChIANet

    Central South UniversityFebruary 25, 20263d_genomechromatinchromatin_contact_prediction+4

    Multimodal deep learning model that predicts protein-mediated chromatin contact maps and loops de novo from protein-binding profiles and sequence.

    DNA & Gene
    10Openness
  • MAP

    Shanghai Jiao Tong UniversityFebruary 25, 2026contrastive_learningdrug_response_predictiongraph_neural_network+6

    Knowledge-graph-grounded model that predicts single-cell transcriptomic responses to small molecules, with zero-shot prediction for unprofiled drugs.

    Single-cellSmall molecule
    12Openness
  • BOTANIC-0

    1177
    Living ModelsFebruary 23, 2026dnafoundation_modelgene_expression+5

    Plant genomic foundation models from 0.1B to 1B parameters, pretrained on 43 phylogenetically diverse plant genomes for variant effect prediction.

    DNA & Gene
    19Openness
  • EnzPlacer

    Iowa State UniversityFebruary 23, 2026contrastive_learningec_number_predictionembeddings+6

    Enzyme function prediction model that uses contrastive learning to assign the first three EC digits to enzymes with functions unseen during training.

    Protein
    59Openness
  • PEINT

    6
    UC BerkeleyFebruary 20, 2026evolutionary_simulationgenerativemolecular_evolution+4

    Protein evolution model that learns indel dynamics and epistasis from unaligned sequences, simulating trajectories that yield functional proteins.

    Protein
    11Openness
  • JEPA-DNA

    178
    NVIDIAFebruary 19, 2026dnafoundation_modelgenomics+5

    Genomic foundation model training framework whose joint-embedding predictive objective learns functional representations of masked DNA, not tokens.

    DNA & Gene
    54Openness
  • OncoBERT

    National Cancer InstituteFebruary 19, 2026bertlanguage_modeloncology+7

    BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.

    DNA & Gene
    7Openness
  • CLM-X

    Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6

    Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.

    Single-cell
    4Openness
  • BOND-PEP

    University of SydneyFebruary 18, 2026de_novo_designgenerativepeptides+3

    Retrieval-augmented framework for de novo peptide binder design that conditions generation on retrieved, structurally aligned binding evidence.

    Protein
    5Openness
  • MMPT-RAG

    Emory UniversityFebruary 18, 2026drug_discoveryfoundation_modelgenerative+3

    Retrieval-augmented model for matched molecular pair transformations, proposing localized analog edits guided by retrieved reference compounds.

    Small molecule
    16Openness
  • Columbia UniversityFebruary 17, 2026dna_methylationepigenomicsfoundation_model+4

    Transformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.

    DNA & Gene
    10Openness
  • Florida International UniversityFebruary 17, 2026cheminformaticsdebertafoundation_model+4

    SMILES molecular encoder on a DeBERTaV2 backbone, pretrained on 123M PubChem molecules with physicochemical and structural-similarity objectives.

    Small molecule
    25Openness
  • resLens

    3
    George Washington UniversityFebruary 16, 2026genomicslanguage_modelmetagenomics+3

    Genomic language models fine-tuned to detect and classify antibiotic resistance genes, catching divergent ARGs that reference alignment misses.

    DNA & Gene
    11Openness
  • BioKinema

    3
    International Digital Economy AcademyFebruary 15, 2026conformational_samplingdiffusiondrug_discovery+5

    Diffusion model that generates continuous-time, all-atom biomolecular trajectories, reproducing conformational kinetics far more cheaply than MD.

    ProteinSmall molecule
    13Openness
  • evoCancerGPT

    Dana-Farber Cancer InstituteFebruary 14, 2026cancerfoundation_modelgene_expression+5

    Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.

    Single-cell
    11Openness
  • TerraBind

    Terray TherapeuticsFebruary 12, 2026binding_affinitydrug_discoveryfoundation_model+3

    Protein-ligand foundation model that maps coarse-grained structural representations directly to binding affinity, running ~26x faster than Boltz-2.

    ProteinSmall molecule
    24Openness
  • dnaHNet

    2
    Arc Institute +2 othersFebruary 11, 2026dnafoundation_modelgene_essentiality_prediction+7

    Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.

    DNA & Gene
    12Openness
  • IsoDDE

    Isomorphic LabsFebruary 10, 2026binding_affinity_predictiondiffusiondrug_discovery+6

    Unified drug design engine for protein-ligand structure prediction, binding affinity estimation, and compound generation from Isomorphic Labs.

    Protein
    13Openness
  • EVA

    96
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.

    Single-cellRNAPathology
    27Openness
  • AntigenLM

    Chinese Academy of Sciences +1 otherFebruary 9, 2026dnafoundation_modelgenerative+5

    Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.

    DNA & Gene
    5Openness