All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 169–192 of 518 filtered models
CALM-1.0
—3—Contrastive antibody language model predicting antibody-antigen binding specificity from sequence with a dual-encoder, cross-attentive architecture.
Protein10OpennessCellPace
———Temporal diffusion framework for single-cell developmental dynamics, interpolating and forecasting cell states from irregularly sampled time series.
Single-cell9OpennessARCH3D
———Foundation model for 3D genome architecture, using masked locus modeling over genome-wide contact profiles to capture chromosome-scale organization.
DNA & Gene19OpennessChIANet
———Multimodal deep learning model that predicts protein-mediated chromatin contact maps and loops de novo from protein-binding profiles and sequence.
DNA & Gene10OpennessMAP
———Shanghai Jiao Tong UniversityFebruary 25, 2026contrastive_learningdrug_response_predictiongraph_neural_network+6Knowledge-graph-grounded model that predicts single-cell transcriptomic responses to small molecules, with zero-shot prediction for unprofiled drugs.
Single-cellSmall molecule12OpennessBOTANIC-0
—1177Plant genomic foundation models from 0.1B to 1B parameters, pretrained on 43 phylogenetically diverse plant genomes for variant effect prediction.
DNA & Gene19OpennessEnzPlacer
———Enzyme function prediction model that uses contrastive learning to assign the first three EC digits to enzymes with functions unseen during training.
Protein59OpennessPEINT
—6—Protein evolution model that learns indel dynamics and epistasis from unaligned sequences, simulating trajectories that yield functional proteins.
Protein11OpennessOncoBERT
———BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.
DNA & Gene7OpennessCLM-X
———Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.
Single-cell4OpennessBOND-PEP
———Retrieval-augmented framework for de novo peptide binder design that conditions generation on retrieved, structurally aligned binding evidence.
Protein5OpennessMMPT-RAG
———Retrieval-augmented model for matched molecular pair transformations, proposing localized analog edits guided by retrieved reference compounds.
Small molecule16OpennessTransformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.
DNA & Gene10OpennessMolDeBERTa
4—5SMILES molecular encoder on a DeBERTaV2 backbone, pretrained on 123M PubChem molecules with physicochemical and structural-similarity objectives.
Small molecule25OpennessresLens
—3—Genomic language models fine-tuned to detect and classify antibiotic resistance genes, catching divergent ARGs that reference alignment misses.
DNA & Gene11OpennessBioKinema
—3—International Digital Economy AcademyFebruary 15, 2026conformational_samplingdiffusiondrug_discovery+5Diffusion model that generates continuous-time, all-atom biomolecular trajectories, reproducing conformational kinetics far more cheaply than MD.
ProteinSmall molecule13OpennessevoCancerGPT
———Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.
Single-cell11OpennessTerraBind
———Protein-ligand foundation model that maps coarse-grained structural representations directly to binding affinity, running ~26x faster than Boltz-2.
ProteinSmall molecule24OpennessdnaHNet
—2—Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.
DNA & Gene12OpennessIsoDDE
———Unified drug design engine for protein-ligand structure prediction, binding affinity estimation, and compound generation from Isomorphic Labs.
Protein13OpennessEVA
——96Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessAntigenLM
———Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.
DNA & Gene5Openness