TIGEM
A Telethon-funded research institute near Naples, Italy, studying the mechanisms of rare genetic diseases and developing therapies for them.
Overview
TIGEM, the Telethon Institute of Genetics and Medicine, is a research institute in Pozzuoli, near Naples, Italy. Founded by Fondazione Telethon, TIGEM investigates the molecular and genetic mechanisms underlying inherited human diseases and develops approaches toward their treatment. It maintains close research ties with Università di Napoli Federico II.
Models (2)
Autoregressive DNA foundation model for variant effect prediction, using 6-mer tokenization to match Evo2-7B win rates at far higher throughput.
Learning-to-rank variant effect predictor that aligns overlapping deep mutational scanning assays into an assay-agnostic tolerance measure.