All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 145–168 of 552 filtered models
CLM-X
———Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.
Single-cell4OpennessMMPT-RAG
———Retrieval-augmented model for matched molecular pair transformations, proposing localized analog edits guided by retrieved reference compounds.
Small molecule16OpennessTransformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.
DNA & Gene10OpennessProtFlow
—2—Flow-matching generative model for peptide sequence design that learns the protein semantic distribution, fine-tuned for antimicrobial peptides.
Protein16OpennessMolDeBERTa
4—5SMILES molecular encoder on a DeBERTaV2 backbone, pretrained on 123M PubChem molecules with physicochemical and structural-similarity objectives.
Small molecule25OpennessSEAL
484—Vision-omics finetuning that aligns pathology foundation models with spatial transcriptomics so morphology features predict local gene expression.
PathologySpatial omics32OpennessevoCancerGPT
———Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.
Single-cell11OpennessUBio-MolFM
33—5Universal all-atom machine-learning force field for molecular dynamics, with ab initio-level accuracy on solvated biomolecules of ~1,500 atoms.
Small moleculeProtein81OpennessSTPAINTER
———University of Science and Technology of China +2 othersFebruary 13, 2026cancerdiffusionfoundation_model+4Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.
Spatial omicsSingle-cell4OpennessDERIVE
———Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.
Protein16OpennessTerraBind
———Protein-ligand foundation model that maps coarse-grained structural representations directly to binding affinity, running ~26x faster than Boltz-2.
ProteinSmall molecule24OpennessdnaHNet
—2—Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.
DNA & Gene12OpennessIsoDDE
———Unified drug design engine for protein-ligand structure prediction, binding affinity estimation, and compound generation from Isomorphic Labs.
Protein13OpennessBioCLIP 2.5
77435.3KVision foundation model for the tree of life, scaling BioCLIP 2 to a ViT-H/14 backbone and more organism images for zero-shot species classification.
Imaging93OpennessEVA
——89Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessAntigenLM
———Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.
DNA & Gene5OpennessDecoderTCR
8——Masked language model for T-cell receptor and peptide-MHC binding prediction, with compositional pretraining and non-autoregressive decoding.
Protein56OpennessNUWA
———mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.
RNADNA & Gene16OpennessscDiVa
—1—Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.
Single-cell6OpennessEchoJEPA
3294—Joint-embedding predictive foundation model for echocardiography, pretrained on 18M cardiac ultrasound videos for artifact-robust representations.
Imaging62OpennessOpticalDNA
———Vision-language DNA model that renders genomic sequence as visual layouts, reading regions up to 450,000 bases with about 20x better token efficiency.
DNA & Gene16OpennessProust
9——Causal 309M-parameter protein language model that scores variant fitness zero-shot and generates sequences, reaching 0.390 Spearman on ProteinGym.
Protein9OpennessGENERator-v2
4601—Family of autoregressive genomic foundation models that reconcile k-mer tokenization with single-nucleotide resolution at contexts up to 98k bp.
DNA & Gene86Openness