All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 145168 of 552 filtered models

  • JEPA-DNA

    178
    NVIDIAFebruary 19, 2026dnafoundation_modelgenomics+5

    Genomic foundation model training framework whose joint-embedding predictive objective learns functional representations of masked DNA, not tokens.

    DNA & Gene
    54Openness
  • CLM-X

    Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6

    Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.

    Single-cell
    4Openness
  • MMPT-RAG

    Emory UniversityFebruary 18, 2026drug_discoveryfoundation_modelgenerative+3

    Retrieval-augmented model for matched molecular pair transformations, proposing localized analog edits guided by retrieved reference compounds.

    Small molecule
    16Openness
  • Columbia UniversityFebruary 17, 2026dna_methylationepigenomicsfoundation_model+4

    Transformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.

    DNA & Gene
    10Openness
  • ProtFlow

    2
    Zhejiang UniversityFebruary 17, 2026antimicrobial_peptidesde_novo_designflow_matching+4

    Flow-matching generative model for peptide sequence design that learns the protein semantic distribution, fine-tuned for antimicrobial peptides.

    Protein
    16Openness
  • Florida International UniversityFebruary 17, 2026cheminformaticsdebertafoundation_model+4

    SMILES molecular encoder on a DeBERTaV2 backbone, pretrained on 123M PubChem molecules with physicochemical and structural-similarity objectives.

    Small molecule
    25Openness
  • SEAL

    484
    Mahmood Lab +2 othersFebruary 15, 2026cancer_subtypingfoundation_modelgene_expression_prediction+5

    Vision-omics finetuning that aligns pathology foundation models with spatial transcriptomics so morphology features predict local gene expression.

    PathologySpatial omics
    32Openness
  • evoCancerGPT

    Dana-Farber Cancer InstituteFebruary 14, 2026cancerfoundation_modelgene_expression+5

    Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.

    Single-cell
    11Openness
  • IQuestLabFebruary 13, 2026curriculum_learningfoundation_modelmolecular_dynamics

    Universal all-atom machine-learning force field for molecular dynamics, with ab initio-level accuracy on solvated biomolecules of ~1,500 atoms.

    Small moleculeProtein
    81Openness
  • STPAINTER

    University of Science and Technology of China +2 othersFebruary 13, 2026cancerdiffusionfoundation_model+4

    Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.

    Spatial omicsSingle-cell
    4Openness
  • DERIVE

    Guangzhou National LaboratoryFebruary 12, 2026flow_matchingfoundation_modelgenerative+5

    Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.

    Protein
    16Openness
  • TerraBind

    Terray TherapeuticsFebruary 12, 2026binding_affinitydrug_discoveryfoundation_model+3

    Protein-ligand foundation model that maps coarse-grained structural representations directly to binding affinity, running ~26x faster than Boltz-2.

    ProteinSmall molecule
    24Openness
  • dnaHNet

    2
    Arc Institute +2 othersFebruary 11, 2026dnafoundation_modelgene_essentiality_prediction+7

    Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.

    DNA & Gene
    12Openness
  • IsoDDE

    Isomorphic LabsFebruary 10, 2026binding_affinity_predictiondiffusiondrug_discovery+6

    Unified drug design engine for protein-ligand structure prediction, binding affinity estimation, and compound generation from Isomorphic Labs.

    Protein
    13Openness
  • BioCLIP 2.5

    77435.3K
    Imageomics InstituteFebruary 10, 2026biodiversitycontrastive_learningfoundation_model+6

    Vision foundation model for the tree of life, scaling BioCLIP 2 to a ViT-H/14 backbone and more organism images for zero-shot species classification.

    Imaging
    93Openness
  • EVA

    89
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.

    Single-cellRNAPathology
    27Openness
  • AntigenLM

    Chinese Academy of Sciences +1 otherFebruary 9, 2026dnafoundation_modelgenerative+5

    Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.

    DNA & Gene
    5Openness
  • DecoderTCR

    8
    Biohub +1 otherFebruary 4, 2026contrastive_learningfoundation_modelimmune_repertoire_analysis+5

    Masked language model for T-cell receptor and peptide-MHC binding prediction, with compositional pretraining and non-autoregressive decoding.

    Protein
    56Openness
  • NUWA

    Kitasato UniversityFebruary 4, 2026bertfoundation_modellanguage_model+5

    mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.

    RNADNA & Gene
    16Openness
  • scDiVa

    1
    Renmin University of ChinaFebruary 3, 2026batch_integrationcell_type_annotationdiffusion+6

    Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.

    Single-cell
    6Openness
  • EchoJEPA

    3294
    Bowang LabFebruary 2, 2026cardiac_ultrasoundechocardiographyejection_fraction_estimation+6

    Joint-embedding predictive foundation model for echocardiography, pretrained on 18M cardiac ultrasound videos for artifact-robust representations.

    Imaging
    62Openness
  • OpticalDNA

    Hunan UniversityFebruary 2, 2026dnafoundation_modelgenomics+5

    Vision-language DNA model that renders genomic sequence as visual layouts, reading regions up to 450,000 bases with about 20x better token efficiency.

    DNA & Gene
    16Openness
  • Proust

    9
    ETH ZurichFebruary 2, 2026foundation_modellanguage_modelprotein_design+3

    Causal 309M-parameter protein language model that scores variant fitness zero-shot and generates sequences, reaching 0.390 Spearman on ProteinGym.

    Protein
    9Openness
  • Beijing Zhongguancun Academy +4 othersJanuary 29, 2026autoregressivednafoundation_model+6

    Family of autoregressive genomic foundation models that reconcile k-mer tokenization with single-nucleotide resolution at contexts up to 98k bp.

    DNA & Gene
    86Openness