All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 97–120 of 518 filtered models
MIMIC
37——Generative multimodal foundation model spanning DNA, RNA, and protein, with any-to-any inference across genome, transcriptome, and proteome.
RNAProteinDNA & Gene16OpennessGenNA
———Autoregressive nucleotide-and-text foundation model generating DNA and RNA sequences from natural-language prompts that name species and function.
DNA & GeneRNA16OpennessAF2Dock
151—Protein-protein docking model adapting AlphaFold-Multimer with a docking module and flow-matching training to assemble subunits without MSAs.
Protein77OpennessCellPulse
———Direction-aware foundation model trained on bulk RNA-seq differential-expression profiles to simulate coordinated gene dynamics in viral infection.
Single-cellLanguage model4OpennessH2O
———Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6Pathology foundation model that infers spatial transcriptomics and proteomics directly from routine H&E whole-slide images, with no spatial assay.
PathologySpatial omics7Openness110M-parameter RNA language model that designs sequences from secondary structure, motif, and Gene Ontology constraints via discrete diffusion.
RNA48OpennessRVQ-Alpha
———Single-cell foundation model that tokenizes scRNA-seq into 10 tokens in a Qwen3-4B vocabulary for cell type annotation and perturbation prediction.
Single-cell4OpennessRNABag
———HomiGen Intelligence Technology Co., Ltd.April 22, 2026cancer_detectioncell_type_annotationfoundation_model+6Transcriptome foundation model for precision oncology, generalizing zero-shot across tissue, plasma cfRNA, and tumor-educated platelet modalities.
Single-cell46OpennessOneGenome-Rice
25—15Genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window and a 1.25B-parameter mixture-of-experts transformer.
DNA & Gene90OpennessMMPT-FM
3——Chemical language model that generates matched molecular pair transformations from SMILES and SMARTS to design medicinal-chemistry analogs.
Small moleculeLanguage model82OpennessProtein function prediction model that fuses sequence, structure, text, and interaction embeddings with learned gating to assign Gene Ontology terms.
Protein84OpennessPeptideCLM-2
102—Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.
Small moleculeProtein79OpennessGPT-Rosalind
4.7K——OpenAI's frontier reasoning model for life-sciences research, tuned for multi-step workflows in protein engineering, genomics, and drug discovery.
Language model5OpennessDIA-CLIP
———AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.
Protein11OpennessEncoder-decoder Transformer that generates intrinsically disordered protein sequences conditioned on target conformational-ensemble descriptors.
Protein10OpennessLinkLlama
10115Molecular linker design model fine-tuned from Llama 3 that emits PROTAC and fragment linkers as SMILES from natural-language geometry prompts.
Small molecule27OpennessGerminal
27234—Generative pipeline for epitope-targeted de novo antibody (nanobody) CDR design that yields nanomolar binders from only dozens of designs per antigen.
Protein37OpennessxVERSE
———Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.
Single-cell10OpennessOmniNA
—3101Generative DNA foundation model trained on 91.7M nucleotide sequences and annotations for species classification and mutation effect prediction.
DNA & Gene42OpennessIDiom
———Chinese Academy of SciencesApril 11, 2026foundation_modelintrinsically_disordered_protein_designintrinsically_disordered_region+5Autoregressive language model trained on 37 million intrinsically disordered region sequences, generating IDRs given flanking folded domains.
Protein19OpennessProtenix-v2
2K7—464M-parameter structure prediction and design model that improves antibody-antigen complex accuracy over Protenix-v1 and adds generative VHH design.
Protein81OpennessDISCO
2103—Multimodal diffusion model that co-designs protein sequence and 3D structure around cofactors and small molecules for de novo heme enzyme design.
Protein70OpennessSTORM
—3—Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.
Spatial omicsPathology17Openness