All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 97–120 of 217 filtered models
ProtFlow
—2—Flow-matching generative model for peptide sequence design that learns the protein semantic distribution, fine-tuned for antimicrobial peptides.
Protein16OpennessBioKinema
—3—International Digital Economy AcademyFebruary 15, 2026conformational_samplingdiffusiondrug_discovery+5Diffusion model that generates continuous-time, all-atom biomolecular trajectories, reproducing conformational kinetics far more cheaply than MD.
ProteinSmall molecule13OpennessevoCancerGPT
———Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.
Single-cell11OpennessProtein language model that encodes sequences as discrete words from a learned vocabulary for zero-shot function inference and protein design.
Protein24OpennessPepMirror
61—Latent diffusion model that designs D-peptide binders against native L-protein targets, generalizing across chirality via axial vector features.
Protein67OpennessDERIVE
———Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.
Protein16OpennessAntigenLM
———Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.
DNA & Gene5OpennessE(3)-equivariant diffusion model for macrocycle design that turns acyclic molecules into macrocycles, with a transformer choosing where to cyclize.
Small molecule8OpennessSaDiT
—1—Protein backbone generator running a diffusion transformer over SaProt structural tokens, with an IPA token cache to speed up de novo design.
Protein5OpennessscDFM
447—Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.
Single-cell54OpennessAtomPaint
———Full-atom SE(3)-equivariant diffusion model that inpaints binding interfaces to design proteins that bind DNA, RNA, and small molecules.
ProteinSmall molecule19OpennessPert2Mol
———Multimodal model that designs small molecules from transcriptomic and cell-imaging perturbation phenotypes with a rectified flow transformer.
Small moleculeSingle-cell22OpennessscDiVa
—1—Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.
Single-cell6OpennessCHASE
———Latent flow-matching method that repurposes protein language model embeddings to generate high-fitness protein variants without predictor guidance.
Protein11OpennessMoLF
———Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.
PathologySpatial omics9OpennessEnzyPGM
—2—University of Science and Technology of China +1 otherJanuary 27, 2026de_novo_designenzyme_designgenerative+5Enzyme design model that jointly generates enzyme sequences and substrate-binding pockets, conditioned on functional priors and substrate structure.
ProteinSmall molecule23OpennessLa-Proteina
304—142Partially latent flow-matching model for de novo protein design, jointly generating sequence and all-atom structure for proteins up to 800 residues.
Protein69OpennessPPIFlow
—4—Flow-matching generative model for de novo protein binder backbone design, built on a Pairformer architecture with in silico interface maturation.
Protein4OpennessBioimage restoration model pairing a NAFNet backbone with a perceptual GAN loss, best on LPIPS in 7 of 8 AI4Life microscopy benchmarks.
Imaging16OpennessPepEDiff
2——Zero-shot peptide binder designer that runs diffusion in a pretrained protein embedding space, proposing binders without structure prediction.
Protein62OpennessGenerative transformer for ancestral protein sequence reconstruction that needs no multiple sequence alignment or phylogenetic tree as input.
Protein4OpennessPathDiffusion
151—Evolution-guided diffusion model that generates temporal protein folding pathways, from unfolded chain to native state, rather than static structures.
Protein64OpennessGluFormer
8719—Weizmann Institute of Science +2 othersJanuary 14, 2026continuous_glucose_monitoringfoundation_modelgenerative+6Generative transformer foundation model for continuous glucose monitoring, forecasting glycemia and stratifying health risk from raw glucose traces.
Biosignals60Openness