All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 97120 of 217 filtered models

  • ProtFlow

    2
    Zhejiang UniversityFebruary 17, 2026antimicrobial_peptidesde_novo_designflow_matching+4

    Flow-matching generative model for peptide sequence design that learns the protein semantic distribution, fine-tuned for antimicrobial peptides.

    Protein
    16Openness
  • BioKinema

    3
    International Digital Economy AcademyFebruary 15, 2026conformational_samplingdiffusiondrug_discovery+5

    Diffusion model that generates continuous-time, all-atom biomolecular trajectories, reproducing conformational kinetics far more cheaply than MD.

    ProteinSmall molecule
    13Openness
  • evoCancerGPT

    Dana-Farber Cancer InstituteFebruary 14, 2026cancerfoundation_modelgene_expression+5

    Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.

    Single-cell
    11Openness
  • Tsinghua UniversityFebruary 14, 2026autoregressivecell_biologyde_novo_design+7

    Protein language model that encodes sequences as discrete words from a learned vocabulary for zero-shot function inference and protein design.

    Protein
    24Openness
  • Tsinghua UniversityFebruary 13, 2026chiralityde_novo_designdiffusion+5

    Latent diffusion model that designs D-peptide binders against native L-protein targets, generalizing across chirality via axial vector features.

    Protein
    67Openness
  • DERIVE

    Guangzhou National LaboratoryFebruary 12, 2026flow_matchingfoundation_modelgenerative+5

    Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.

    Protein
    16Openness
  • AntigenLM

    Chinese Academy of Sciences +1 otherFebruary 9, 2026dnafoundation_modelgenerative+5

    Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.

    DNA & Gene
    5Openness
  • Keshav Memorial Engineering CollegeFebruary 6, 2026diffusiondrug_discoverygenerative+3

    E(3)-equivariant diffusion model for macrocycle design that turns acyclic molecules into macrocycles, with a transformer choosing where to cyclize.

    Small molecule
    8Openness
  • SaDiT

    1
    Independent ResearcherFebruary 6, 2026de_novo_designdiffusiongenerative+3

    Protein backbone generator running a diffusion transformer over SaProt structural tokens, with an IPA token cache to speed up de novo design.

    Protein
    5Openness
  • scDFM

    447
    Westlake UniversityFebruary 6, 2026flow_matchinggene_expressiongenerative+4

    Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.

    Single-cell
    54Openness
  • AtomPaint

    Harvard Medical SchoolFebruary 4, 2026binder_designdiffusiongenerative+4

    Full-atom SE(3)-equivariant diffusion model that inpaints binding interfaces to design proteins that bind DNA, RNA, and small molecules.

    ProteinSmall molecule
    19Openness
  • Pert2Mol

    Purdue UniversityFebruary 4, 2026de_novo_designgenerativemolecular_generation+5

    Multimodal model that designs small molecules from transcriptomic and cell-imaging perturbation phenotypes with a rectified flow transformer.

    Small moleculeSingle-cell
    22Openness
  • scDiVa

    1
    Renmin University of ChinaFebruary 3, 2026batch_integrationcell_type_annotationdiffusion+6

    Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.

    Single-cell
    6Openness
  • CHASE

    ETH Zurich +1 otherFebruary 2, 2026autoencoderdirected_evolutionfitness_optimization+4

    Latent flow-matching method that repurposes protein language model embeddings to generate high-fitness protein variants without predictor guidance.

    Protein
    11Openness
  • MoLF

    National Center for Tumor Diseases DresdenFebruary 2, 2026flow_matchinggene_expressiongenerative+5

    Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.

    PathologySpatial omics
    9Openness
  • EnzyPGM

    2
    University of Science and Technology of China +1 otherJanuary 27, 2026de_novo_designenzyme_designgenerative+5

    Enzyme design model that jointly generates enzyme sequences and substrate-binding pockets, conditioned on functional priors and substrate structure.

    ProteinSmall molecule
    23Openness
  • COSMIC

    EPFLJanuary 24, 2026autoencodercell_biologycell_type_annotation+7

    Bidirectional generative framework linking nuclear morphology and gene expression, built on a morphology model trained on 21 million segmented nuclei.

    ImagingSingle-cellSpatial omics
    4Openness
  • La-Proteina

    304142
    NVIDIAJanuary 23, 2026all_atomde_novo_designflow_matching+6

    Partially latent flow-matching model for de novo protein design, jointly generating sequence and all-atom structure for proteins up to 800 residues.

    Protein
    69Openness
  • PPIFlow

    4
    Changping LaboratoryJanuary 22, 2026antibodyde_novo_designflow_matching+5

    Flow-matching generative model for de novo protein binder backbone design, built on a Pairformer architecture with in silico interface maturation.

    Protein
    4Openness
  • Universidad Carlos III de MadridJanuary 22, 2026cnncryo_emdenoising+5

    Bioimage restoration model pairing a NAFNet backbone with a perceptual GAN loss, best on LPIPS in 7 of 8 AI4Life microscopy benchmarks.

    Imaging
    16Openness
  • PepEDiff

    2
    University of CincinnatiJanuary 19, 2026de_novo_designdiffusiongenerative+6

    Zero-shot peptide binder designer that runs diffusion in a pretrained protein embedding space, proposing binders without structure prediction.

    Protein
    62Openness
  • Tel Aviv UniversityJanuary 18, 2026ancestral_sequence_reconstructiongenerativemolecular_evolution+4

    Generative transformer for ancestral protein sequence reconstruction that needs no multiple sequence alignment or phylogenetic tree as input.

    Protein
    4Openness
  • Shandong UniversityJanuary 16, 2026diffusionfolding_pathway_simulationgenerative+5

    Evolution-guided diffusion model that generates temporal protein folding pathways, from unfolded chain to native state, rather than static structures.

    Protein
    64Openness
  • GluFormer

    8719
    Weizmann Institute of Science +2 othersJanuary 14, 2026continuous_glucose_monitoringfoundation_modelgenerative+6

    Generative transformer foundation model for continuous glucose monitoring, forecasting glycemia and stratifying health risk from raw glucose traces.

    Biosignals
    60Openness