All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 97–120 of 552 filtered models
DISCO
2103—Multimodal diffusion model that co-designs protein sequence and 3D structure around cofactors and small molecules for de novo heme enzyme design.
Protein70OpennessGenoJEPA
———Beijing University of Posts and TelecommunicationsApril 6, 2026foundation_modelgenomicsrepresentation_learning+4Genomic foundation model that learns DNA representations by predicting masked regions in latent space rather than reconstructing raw nucleotides.
DNA & Gene22OpennessMuPD
———Diffusion-transformer pathology model embedding H&E histology, RNA profiles, and clinical text in a latent space for zero-shot cross-modal synthesis.
PathologySpatial omics15OpennessSTORM
—3—Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.
Spatial omicsPathology17OpennessPlantCAD2
97—4.2KLong-context plant DNA language model, 676M parameters on a Mamba2 backbone, pretrained on 65 angiosperm genomes for cross-species variant annotation.
DNA & Gene69OpennessmRNA-GPT
42—Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.
RNA10OpennessscLong
2210—Billion-parameter single-cell foundation model with self-attention over 28,000 human genes, adding Gene Ontology priors via a graph neural network.
Single-cell29OpennessDigepath
———Gastrointestinal histopathology foundation model pretrained on 353 million multi-scale patches from 210,000 H&E whole-slide images of GI tissue.
Pathology15OpennessRegFormer
———Single-cell foundation model combining regulatory network priors with a Mamba backbone for clustering, batch integration, and perturbation modeling.
Single-cell10OpennessProtiCelli
241—Generative imaging model simulating single-cell fluorescence microscopy for all 12,800 human proteins in the Human Protein Atlas.
Imaging51OpennessEnzyGen2
30——Protein foundation model for de novo enzyme design that co-designs sequence and 3D structure under small-molecule ligand guidance, at 730M parameters.
ProteinSmall molecule89OpennessEEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.
Biosignals18OpennessLingshu-Cell
—3—Virtual cell model using masked discrete diffusion over the whole transcriptome to simulate scRNA-seq perturbation responses across tissues.
Single-cell21OpennessIDPForge
162—Chinese Academy of SciencesMarch 25, 2026conformational_ensembleconformational_ensemble_generationdiffusion+7Protein-language diffusion model generating all-atom conformational ensembles for intrinsically disordered proteins and disordered regions.
Protein29OpennessEVA
821—Generative RNA foundation model trained on 114 million full-length sequences for de novo design of tRNAs, aptamers, CRISPR guide RNAs, and mRNAs.
RNA72OpennessSuiren-1.0
171—Molecular foundation models pretrained on density functional theory data, encoding 3D geometry and quantum behavior for ADMET and drug discovery.
Small molecule46OpennessGenBio-PathFM
372714Histopathology foundation model with 1.1B parameters, trained entirely on public data using JEDI, a dual-stage strategy combining JEPA and DINO.
Pathology21OpennessProteinSage
———Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.
Protein12OpennessSELFormerMM
3——Multimodal molecular foundation model fusing SELFIES, 2D graphs, text, and knowledge graphs via contrastive pretraining for property prediction.
Small molecule55OpennessRNAElectra
———Single-nucleotide-resolution RNA foundation model pretrained on non-coding RNAs with ELECTRA-style replaced-token detection for regulatory inference.
RNA23OpennessSCALE
———Virtual cell foundation model predicting single-cell responses to genetic, chemical, and cytokine perturbations with conditional flow matching.
Single-cell19OpennessX-Cell
1068—Diffusion language model with 4.9 billion parameters that predicts genome-wide CRISPRi perturbation responses in single-cell transcriptomes.
Single-cell20OpennessProteina-Complexa
39821148Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.
Protein68Openness