All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 97120 of 552 filtered models

  • DISCO

    2103
    FutureHouse +2 othersApril 6, 2026all_atomcofactorde_novo_design+9

    Multimodal diffusion model that co-designs protein sequence and 3D structure around cofactors and small molecules for de novo heme enzyme design.

    Protein
    70Openness
  • GenoJEPA

    Beijing University of Posts and TelecommunicationsApril 6, 2026foundation_modelgenomicsrepresentation_learning+4

    Genomic foundation model that learns DNA representations by predicting masked regions in latent space rather than reconstructing raw nucleotides.

    DNA & Gene
    22Openness
  • MuPD

    Stanford UniversityApril 4, 2026data_augmentationdiffusion_transformerfoundation_model+7

    Diffusion-transformer pathology model embedding H&E histology, RNA profiles, and clinical text in a latent space for zero-shot cross-modal synthesis.

    PathologySpatial omics
    15Openness
  • STORM

    3
    Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6

    Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.

    Spatial omicsPathology
    17Openness
  • PlantCAD2

    974.2K
    Cornell UniversityApril 3, 2026foundation_modelfunctional_annotationgene_expression+7

    Long-context plant DNA language model, 676M parameters on a Mamba2 backbone, pretrained on 65 angiosperm genomes for cross-species variant annotation.

    DNA & Gene
    69Openness
  • Chinese Academy of SciencesApril 2, 2026codoncodon_optimizationfoundation_model+8

    Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.

    RNA
    10Openness
  • scLong

    2210
    Chinese Academy of SciencesApril 1, 2026batch_integrationcell_type_annotationfoundation_model+5

    Billion-parameter single-cell foundation model with self-attention over 28,000 human genes, adding Gene Ontology priors via a graph neural network.

    Single-cell
    29Openness
  • Digepath

    Chinese Academy of SciencesApril 1, 2026cancer_diagnosisfoundation_modelgastrointestinal_cancer+7

    Gastrointestinal histopathology foundation model pretrained on 353 million multi-scale patches from 210,000 H&E whole-slide images of GI tissue.

    Pathology
    15Openness
  • RegFormer

    BGI ResearchApril 1, 2026batch_integrationcell_clusteringdrug_response_prediction+5

    Single-cell foundation model combining regulatory network priors with a Mamba backbone for clustering, batch integration, and perturbation modeling.

    Single-cell
    10Openness
  • Human Protein Atlas +1 otherMarch 31, 2026diffusionfoundation_modelgenerative+4

    Generative imaging model simulating single-cell fluorescence microscopy for all 12,800 human proteins in the Human Protein Atlas.

    Imaging
    51Openness
  • EnzyGen2

    30
    Carnegie Mellon UniversityMarch 31, 2026de_novo_designenzyme_designfoundation_model+5

    Protein foundation model for de novo enzyme design that co-designs sequence and 3D structure under small-molecule ligand guidance, at 730M parameters.

    ProteinSmall molecule
    89Openness
  • Carnegie Mellon UniversityMarch 27, 2026brain_computer_interfaceeegfoundation_model+5

    EEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.

    Biosignals
    18Openness
  • DAMO AcademyMarch 26, 2026diffusionfoundation_modelgene_expression+4

    Virtual cell model using masked discrete diffusion over the whole transcriptome to simulate scRNA-seq perturbation responses across tissues.

    Single-cell
    21Openness
  • IDPForge

    162
    Chinese Academy of SciencesMarch 25, 2026conformational_ensembleconformational_ensemble_generationdiffusion+7

    Protein-language diffusion model generating all-atom conformational ensembles for intrinsically disordered proteins and disordered regions.

    Protein
    29Openness
  • EVA

    821
    GENTEL LabMarch 24, 2026aptameraptamer_designcircular_rna+9

    Generative RNA foundation model trained on 114 million full-length sequences for de novo design of tRNAs, aptamers, CRISPR guide RNAs, and mRNAs.

    RNA
    72Openness
  • Golab (SAIS Physics Lab)March 23, 2026diffusiondrug_discoveryfoundation_model+4

    Molecular foundation models pretrained on density functional theory data, encoding 3D geometry and quantum behavior for ADMET and drug discovery.

    Small molecule
    46Openness
  • genbio.aiMarch 20, 2026foundation_modelhistologyrepresentation_learning+3

    Histopathology foundation model with 1.1B parameters, trained entirely on public data using JEDI, a dual-stage strategy combining JEPA and DINO.

    Pathology
    21Openness
  • ProteinSage

    BioMapMarch 19, 2026foundation_modelprotein_structurerepresentation_learning+3

    Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.

    Protein
    12Openness
  • Hacettepe UniversityMarch 19, 2026cheminformaticscontrastive_learningdrug_discovery+5

    Multimodal molecular foundation model fusing SELFIES, 2D graphs, text, and knowledge graphs via contrastive pretraining for property prediction.

    Small molecule
    55Openness
  • ATMOS

    4
    MilaMarch 18, 2026conformation_generationdiffusionfoundation_model+5

    Generative foundation model that produces atom-level molecular dynamics trajectories for protein monomers and protein-ligand complexes.

    Protein
    11Openness
  • RNAElectra

    Australian National UniversityMarch 17, 2026foundation_modelself_supervisedstructure_prediction+1

    Single-nucleotide-resolution RNA foundation model pretrained on non-coding RNAs with ELECTRA-style replaced-token detection for regulatory inference.

    RNA
    23Openness
  • SCALE

    Shanghai AI LaboratoryMarch 17, 2026flow_matchingfoundation_modelgenerative+4

    Virtual cell foundation model predicting single-cell responses to genetic, chemical, and cytokine perturbations with conditional flow matching.

    Single-cell
    19Openness
  • X-Cell

    1068
    Xaira TherapeuticsMarch 17, 2026crispr_perturbationdiffusionfoundation_model+4

    Diffusion language model with 4.9 billion parameters that predicts genome-wide CRISPRi perturbation responses in single-cell transcriptomes.

    Single-cell
    20Openness
  • NVIDIAMarch 16, 2026all_atomde_novo_designflow_matching+6

    Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.

    Protein
    68Openness