All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 7396 of 552 filtered models

  • Proteo-R1

    6453.2K
    Stanford University +3 othersMay 1, 2026antibodyde_novo_designdiffusion+5

    Reasoning-guided foundation model for de novo antibody CDR design, pairing a multimodal LLM understanding expert with a Boltz-1 diffusion expert.

    Protein
    53Openness
  • Carbon

    2006.4K
    Hugging Face +2 othersMay 1, 2026dnafoundation_modelgenerative+3

    Autoregressive DNA foundation model for variant effect prediction, using 6-mer tokenization to match Evo2-7B win rates at far higher throughput.

    DNA & Gene
    93Openness
  • CoMole

    University of Notre DameMay 1, 2026de_novo_designdiffusiondrug_discovery+7

    Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.

    Small molecule
    23Openness
  • Emory University +2 othersApril 30, 2026brain_age_estimationdisease_classificationfoundation_model+6

    Self-supervised brain MRI foundation model built on DINOv3, pretrained on roughly 6.6 million unlabeled axial slices for neuroimaging tasks.

    Imaging
    49Openness
  • Phoenix

    Helmholtz Munich +1 otherApril 29, 2026cell_type_annotationflow_matchingfoundation_model+6

    Virtual spatial transcriptomics foundation model predicting pan-cancer, spatially-resolved single-cell gene expression from H&E histology slides.

    PathologySpatial omics
    8Openness
  • scPert

    Zhejiang University School of MedicineApril 28, 2026drug_discoveryfoundation_modelgene_expression+4

    Multi-modal transformer fusing LLM gene embeddings with biological knowledge graphs to predict single-cell responses to genetic perturbations.

    Single-cell
    14Openness
  • HyperMap

    1
    University of California, San Diego +1 otherApril 27, 2026crisprdrug_discoveryfew_shot+7

    Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few measured seed perturbations.

    Single-cell
    11Openness
  • MIMIC

    37
    Polymathic AIApril 27, 2026foundation_modelgenerativegenomics+6

    Generative multimodal foundation model spanning DNA, RNA, and protein, with any-to-any inference across genome, transcriptome, and proteome.

    RNAProteinDNA & Gene
    16Openness
  • GenNA

    Zhejiang UniversityApril 24, 2026de_novo_designfoundation_modelgenerative+5

    Autoregressive nucleotide-and-text foundation model generating DNA and RNA sequences from natural-language prompts that name species and function.

    DNA & GeneRNA
    16Openness
  • CellPulse

    Wuhan Institute of VirologyApril 24, 2026drug_discoveryfoundation_modelgene_expression+5

    Direction-aware foundation model trained on bulk RNA-seq differential-expression profiles to simulate coordinated gene dynamics in viral infection.

    Single-cellLanguage model
    4Openness
  • H2O

    Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6

    Pathology foundation model that infers spatial transcriptomics and proteomics directly from routine H&E whole-slide images, with no spatial assay.

    PathologySpatial omics
    7Openness
  • Aiki-XP

    AikiumApril 23, 2026foundation_modelgenomicsmultimodal+5

    Leakage-controlled multimodal model predicting within-species relative protein expression across 385 bacterial species, with transfer to unseen phyla.

    Protein
    96Openness
  • RNABag

    HomiGen Intelligence Technology Co., Ltd.April 22, 2026cancer_detectioncell_type_annotationfoundation_model+6

    Transcriptome foundation model for precision oncology, generalizing zero-shot across tissue, plasma cfRNA, and tumor-educated platelet modalities.

    Single-cell
    46Openness
  • Mach-1

    34
    Broad InstituteApril 21, 2026foundation_modelisoform_abundance_predictionpre_mrna+8

    Long-context RNA foundation model that predicts splicing, isoform abundance, and variant effects from 64 kb of unspliced pre-mRNA sequence.

    RNA
    39Openness
  • Zhejiang Lab +1 otherApril 21, 2026chromatinchromatin_accessibilitydna+8

    Genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window and a 1.25B-parameter mixture-of-experts transformer.

    DNA & Gene
    90Openness
  • MMPT-FM

    3
    Merck & Co. +1 otherApril 20, 2026analog_designdrug_discoveryfoundation_model+2

    Chemical language model that generates matched molecular pair transformations from SMILES and SMARTS to design medicinal-chemistry analogs.

    Small moleculeLanguage model
    82Openness
  • University of Texas at Austin +1 otherApril 17, 2026bertdrug_discoveryfoundation_model+7

    Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.

    Small moleculeProtein
    79Openness
  • GPT-Rosalind

    4.7K
    OpenAIApril 16, 2026dnadrug_discoveryfoundation_model+9

    OpenAI's frontier reasoning model for life-sciences research, tuned for multi-step workflows in protein engineering, genomics, and drug discovery.

    Language model
    5Openness
  • DIA-CLIP

    AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6

    Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.

    Protein
    11Openness
  • xVERSE

    Duke UniversityApril 14, 2026batch_effect_correctionfoundation_modelgenerative+5

    Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.

    Single-cell
    10Openness
  • OmniNA

    3101
    Beijing Institute of Genomics +1 otherApril 13, 2026dnafoundation_modelgenome+7

    Generative DNA foundation model trained on 91.7M nucleotide sequences and annotations for species classification and mutation effect prediction.

    DNA & Gene
    42Openness
  • IDiom

    Chinese Academy of SciencesApril 11, 2026foundation_modelintrinsically_disordered_protein_designintrinsically_disordered_region+5

    Autoregressive language model trained on 37 million intrinsically disordered region sequences, generating IDRs given flanking folded domains.

    Protein
    19Openness
  • Deep-Plant

    1
    Colorado State University +1 otherApril 9, 2026chromatincnnenhancer_prediction+6

    Chromatin-informed foundation model predicting regulatory activity and chromatin state directly from plant genomic sequence in Arabidopsis and rice.

    DNA & Gene
    87Openness
  • ByteDance AI LabApril 8, 2026antibodyantibody_designde_novo_design+6

    464M-parameter structure prediction and design model that improves antibody-antigen complex accuracy over Protenix-v1 and adds generative VHH design.

    Protein
    81Openness