All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 73–96 of 552 filtered models
Proteo-R1
6453.2KReasoning-guided foundation model for de novo antibody CDR design, pairing a multimodal LLM understanding expert with a Boltz-1 diffusion expert.
Protein53OpennessCarbon
200—6.4KAutoregressive DNA foundation model for variant effect prediction, using 6-mer tokenization to match Evo2-7B win rates at far higher throughput.
DNA & Gene93OpennessCoMole
———Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.
Small molecule23OpennessBrainDINO
53—Emory University +2 othersApril 30, 2026brain_age_estimationdisease_classificationfoundation_model+6Self-supervised brain MRI foundation model built on DINOv3, pretrained on roughly 6.6 million unlabeled axial slices for neuroimaging tasks.
Imaging49OpennessPhoenix
———Virtual spatial transcriptomics foundation model predicting pan-cancer, spatially-resolved single-cell gene expression from H&E histology slides.
PathologySpatial omics8OpennessscPert
———Multi-modal transformer fusing LLM gene embeddings with biological knowledge graphs to predict single-cell responses to genetic perturbations.
Single-cell14OpennessHyperMap
—1—Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few measured seed perturbations.
Single-cell11OpennessMIMIC
37——Generative multimodal foundation model spanning DNA, RNA, and protein, with any-to-any inference across genome, transcriptome, and proteome.
RNAProteinDNA & Gene16OpennessGenNA
———Autoregressive nucleotide-and-text foundation model generating DNA and RNA sequences from natural-language prompts that name species and function.
DNA & GeneRNA16OpennessCellPulse
———Direction-aware foundation model trained on bulk RNA-seq differential-expression profiles to simulate coordinated gene dynamics in viral infection.
Single-cellLanguage model4OpennessH2O
———Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6Pathology foundation model that infers spatial transcriptomics and proteomics directly from routine H&E whole-slide images, with no spatial assay.
PathologySpatial omics7OpennessRNABag
———HomiGen Intelligence Technology Co., Ltd.April 22, 2026cancer_detectioncell_type_annotationfoundation_model+6Transcriptome foundation model for precision oncology, generalizing zero-shot across tissue, plasma cfRNA, and tumor-educated platelet modalities.
Single-cell46OpennessMach-1
34—Long-context RNA foundation model that predicts splicing, isoform abundance, and variant effects from 64 kb of unspliced pre-mRNA sequence.
RNA39OpennessOneGenome-Rice
25—15Genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window and a 1.25B-parameter mixture-of-experts transformer.
DNA & Gene90OpennessMMPT-FM
3——Chemical language model that generates matched molecular pair transformations from SMILES and SMARTS to design medicinal-chemistry analogs.
Small moleculeLanguage model82OpennessPeptideCLM-2
102—Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.
Small moleculeProtein79OpennessGPT-Rosalind
4.7K——OpenAI's frontier reasoning model for life-sciences research, tuned for multi-step workflows in protein engineering, genomics, and drug discovery.
Language model5OpennessDIA-CLIP
———AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.
Protein11OpennessxVERSE
———Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.
Single-cell10OpennessOmniNA
—3101Generative DNA foundation model trained on 91.7M nucleotide sequences and annotations for species classification and mutation effect prediction.
DNA & Gene42OpennessIDiom
———Chinese Academy of SciencesApril 11, 2026foundation_modelintrinsically_disordered_protein_designintrinsically_disordered_region+5Autoregressive language model trained on 37 million intrinsically disordered region sequences, generating IDRs given flanking folded domains.
Protein19OpennessDeep-Plant
1——Chromatin-informed foundation model predicting regulatory activity and chromatin state directly from plant genomic sequence in Arabidopsis and rice.
DNA & Gene87OpennessProtenix-v2
2K7—464M-parameter structure prediction and design model that improves antibody-antigen complex accuracy over Protenix-v1 and adds generative VHH design.
Protein81Openness