All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 49–72 of 86 filtered models
Chromnitron
261—Multimodal foundation model predicting genome-wide binding of chromatin-associated proteins from protein sequence, DNA sequence, and chromatin state.
DNA & GeneProtein25OpennessAlphaGenome
2K154—DNA foundation model that predicts thousands of functional genomic tracks, from expression and splicing to chromatin, at single base-pair resolution.
DNA & Gene49Openness- University of Oregon +1 otherJune 24, 2025ancestral_recombination_graph_inferencecoalescence_time_estimationgenomics+4
Decoder-only transformer that recasts ancestral recombination graph inference as next-token prediction, estimating coalescence times from variation.
DNA & Gene83Openness LucaVirus
745155Multimodal viral foundation model over nucleotide and protein sequence, built for virus discovery, function annotation, and antibody design.
DNA & GeneProtein88OpennessBioMed Multi-Omic
62—23Open-source framework for building RNA and DNA foundation models, featuring WCED pretraining for transcriptomics and SNP-aware encoding for genomics.
DNA & Gene84OpennessseqLens
7——Genomic language models with disentangled attention, pretrained on prokaryotic and eukaryotic genomes for sequence classification and variant effects.
DNA & Gene18OpennessEvo 2
4K28811.8KGenomic foundation model trained on 9.3 trillion DNA base pairs across all domains of life, with 40B parameters and a 1-million-token context.
DNA & Gene92OpennessSNPBag
15——Genomics foundation model for genome-scale SNP analysis, handling imputation, phasing, ancestry, and relatedness from one 0.8B-parameter checkpoint.
DNA & Gene29OpennessEvo
1.5K2501.8KGenomic foundation model with 7B parameters that models prokaryotic DNA, RNA, and protein at single-nucleotide resolution over a 131k-token context.
DNA & Gene70OpennessLOL-EVE
238Conditional autoregressive genomic language model trained on 13.6M mammalian promoters, scoring promoter variants, including indels, zero-shot.
DNA & Gene89OpennessMed-Gemini
—410—Family of medical multimodal models built on Gemini, adding uncertainty-guided web search, custom modality encoders, and long-context EHR reasoning.
Language modelImaging8OpennessPuffin
10655—Interpretable model of human transcription initiation that decomposes promoter activity into a minimal set of sequence rules at base-pair resolution.
DNA & Gene23OpennessOpenCRISPR-1
1.2K80—AI-designed CRISPR-Cas9 gene editor generated by protein language models trained on 1.2 million CRISPR operons and shown to edit the human genome.
Protein16OpennessgLM
9193—Genomic language model trained on metagenomic scaffolds that learns protein co-regulation and function by modeling gene context and operon structure.
DNA & Gene30OpennessCaduceus
2482232.6KBidirectional, reverse-complement equivariant DNA language models built on Mamba state space models for long-range variant effect prediction.
DNA & Gene86OpennessGPN-MSA
34990216DNA language model for variant effect prediction across coding and non-coding regions, using whole-genome alignments of 100 vertebrate species.
DNA & Gene87OpennessAlphaMissense
6351.7K—Missense variant pathogenicity predictor built on AlphaFold 2 representations, scoring variants across the human proteome at 0.940 AuROC on ClinVar.
Protein44OpennessGEARS
386376—Perturbation prediction model that forecasts transcriptional responses to multi-gene CRISPR perturbations from scRNA-seq and a gene-gene graph.
Single-cell68OpennessMed-PaLM M
—552—Google's generalist multimodal biomedical AI that encodes clinical text, medical images, and genomics with a single set of weights across 14 tasks.
ImagingLanguage model25Openness