All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 62 filtered models
EVA
——89Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessscDFM
447—Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.
Single-cell54OpennessPert2Mol
———Multimodal model that designs small molecules from transcriptomic and cell-imaging perturbation phenotypes with a rectified flow transformer.
Small moleculeSingle-cell22OpennessscDiVa
—1—Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.
Single-cell6OpennessSingle-cell RNA-seq language model that treats cells as gene-expression tokens, synthesizing whole transcriptomes from tissue and disease metadata.
Single-cellSpatial omics2OpennessOKR-CELL
———Cross-modal single-cell foundation model that aligns gene-expression profiles with LLM-enriched cell descriptions in a shared embedding space.
Single-cellLanguage model23OpennessGEMGen
—2—Generative language model for phenotype-driven drug discovery, proposing small-molecule structures from up- and down-regulated gene signatures.
Small moleculeSingle-cell9OpennessOmniCell
—1—Transcriptomic foundation model pretrained on 67M single-cell and spatial profiles, modeling gene expression and inter-cellular dependencies.
Single-cellSpatial omics9OpennessM-Optimus
———Multimodal foundation model that embeds histology, transcriptomics, and clinical records in one space for patient stratification and target discovery.
PathologySpatial omicsSingle-cell3OpennessEXAONE Path 2.5
5280Pathology foundation model that aligns whole-slide images with genomic, epigenetic, and transcriptomic data for patient-level tumor representations.
PathologySpatial omics14OpennessPanFoMa
2——Pan-cancer single-cell foundation model with a hybrid Transformer-Mamba architecture, released with the PanFoMaBench cancer evaluation benchmark.
Single-cell13OpennessISTS
———Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.
Single-cellDNA & Gene20OpennessPULSAR
364166Hierarchical single-cell foundation model that turns scRNA-seq profiles into zero-shot donor-level embeddings for disease and biomarker prediction.
Single-cellProtein58OpennessscLDM
587—Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.
Single-cell75OpennessscLDM.CD4
9—198Single-cell latent diffusion model fine-tuned on 14.5 million CD4+ T cells to simulate transcriptomic effects of single-gene perturbations.
Single-cell75OpennessTahoe-x1
1591539Perturbation-trained single-cell foundation models (up to 3B parameters) that jointly model genes, cells, and compounds for precision oncology tasks.
Single-cellSmall molecule95OpennessTabPFN-Wide
—7—Tabular foundation model adapted for extreme feature counts, enabling in-context prediction on wide omics tables with tens of thousands of features.
DNA & GeneSingle-cell32OpennessrBio
14616—Reasoning language model post-trained on virtual cell simulations, answering questions about gene perturbations and their effects in natural language.
Language model60OpennessGREmLN
38——Single-cell transcriptomics foundation model that encodes gene regulatory network structure into self-attention through graph signal processing.
Single-cell80OpennessZebraformer
—1—Zebrafish single-cell foundation model built on the Geneformer framework, producing frozen gene and cell embeddings for developmental analysis.
Single-cell46OpennessSTATE
623117250Virtual cell transformer that predicts how cells respond to genetic, chemical, or signaling perturbations, generalizing to unseen cellular contexts.
Single-cell21Openness