All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 62 filtered models

  • EVA

    89
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.

    Single-cellRNAPathology
    27Openness
  • scDFM

    447
    Westlake UniversityFebruary 6, 2026flow_matchinggene_expressiongenerative+4

    Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.

    Single-cell
    54Openness
  • Pert2Mol

    Purdue UniversityFebruary 4, 2026de_novo_designgenerativemolecular_generation+5

    Multimodal model that designs small molecules from transcriptomic and cell-imaging perturbation phenotypes with a rectified flow transformer.

    Small moleculeSingle-cell
    22Openness
  • scDiVa

    1
    Renmin University of ChinaFebruary 3, 2026batch_integrationcell_type_annotationdiffusion+6

    Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.

    Single-cell
    6Openness
  • Seoul National University HospitalJanuary 12, 2026cancercell_type_annotationdata_generation+6

    Single-cell RNA-seq language model that treats cells as gene-expression tokens, synthesizing whole transcriptomes from tissue and disease metadata.

    Single-cellSpatial omics
    2Openness
  • OKR-CELL

    BGI ResearchJanuary 9, 2026batch_effect_correctioncell_biologycell_clustering+7

    Cross-modal single-cell foundation model that aligns gene-expression profiles with LLM-enriched cell descriptions in a shared embedding space.

    Single-cellLanguage model
    23Openness
  • GEMGen

    2
    Westlake University +1 otherJanuary 3, 2026de_novo_designdrug_discoverygenerative+5

    Generative language model for phenotype-driven drug discovery, proposing small-molecule structures from up- and down-regulated gene signatures.

    Small moleculeSingle-cell
    9Openness
  • OmniCell

    1
    BGI ResearchDecember 29, 2025cell_type_annotationfoundation_modelgene_expression+6

    Transcriptomic foundation model pretrained on 67M single-cell and spatial profiles, modeling gene expression and inter-cellular dependencies.

    Single-cellSpatial omics
    9Openness
  • M-Optimus

    BioptimusDecember 17, 2025clinical_outcome_predictiondrug_target_identificationfoundation_model+8

    Multimodal foundation model that embeds histology, transcriptomics, and clinical records in one space for patient stratification and target discovery.

    PathologySpatial omicsSingle-cell
    3Openness
  • LG AI ResearchDecember 16, 2025biomarker_predictioncancer_subtypingcontrastive_learning+8

    Pathology foundation model that aligns whole-slide images with genomic, epigenetic, and transcriptomic data for patient-level tumor representations.

    PathologySpatial omics
    14Openness
  • cfRNA-ICL

    Eigen BioDecember 13, 2025cancer_classificationcell_free_rnaearly_cancer_detection+7

    In-context learning model for cell-free RNA, meta-trained on synthetic tasks from a cfRNA structural causal model for few-shot cancer classification.

    Single-cellRNA
    8Openness
  • PanFoMa

    2
    Shanghai Jiao Tong University +4 othersDecember 2, 2025batch_correctioncancercell_type_annotation+7

    Pan-cancer single-cell foundation model with a hybrid Transformer-Mamba architecture, released with the PanFoMaBench cancer evaluation benchmark.

    Single-cell
    13Openness
  • ISTS

    New York UniversityDecember 2, 2025autoencoderbertcancer_classification+9

    Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.

    Single-cellDNA & Gene
    20Openness
  • PULSAR

    364166
    Stanford UniversityNovember 26, 2025biomarker_predictiondisease_classificationfoundation_model+6

    Hierarchical single-cell foundation model that turns scRNA-seq profiles into zero-shot donor-level embeddings for disease and biomarker prediction.

    Single-cellProtein
    58Openness
  • scLDM

    587
    Chan Zuckerberg InitiativeNovember 4, 2025autoencodercell_biologydata_augmentation+8

    Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.

    Single-cell
    75Openness
  • scLDM.CD4

    9198
    Chan Zuckerberg InitiativeNovember 4, 2025autoencodercell_biologydiffusion+7

    Single-cell latent diffusion model fine-tuned on 14.5 million CD4+ T cells to simulate transcriptomic effects of single-gene perturbations.

    Single-cell
    75Openness
  • Tahoe-x1

    1591539
    Tahoe TherapeuticsOctober 23, 2025cancercell_type_annotationdrug_discovery+7

    Perturbation-trained single-cell foundation models (up to 3B parameters) that jointly model genes, cells, and compounds for precision oncology tasks.

    Single-cellSmall molecule
    95Openness
  • University of TübingenOctober 7, 2025biomarker_discoveryfoundation_modelgenomics+3

    Tabular foundation model adapted for extreme feature counts, enabling in-context prediction on wide omics tables with tens of thousands of features.

    DNA & GeneSingle-cell
    32Openness
  • OwkinZero

    1
    OwkinAugust 22, 2025drug_discoveryfoundation_modelreinforcement_learning+2

    Biological reasoning language model that post-trains Qwen3 with reinforcement learning from verifiable rewards for drug-discovery tasks.

    Language model
    15Openness
  • rBio

    14616
    Chan Zuckerberg InitiativeAugust 18, 2025cell_biologyfoundation_modelreinforcement_learning+2

    Reasoning language model post-trained on virtual cell simulations, answering questions about gene perturbations and their effects in natural language.

    Language model
    60Openness
  • GREmLN

    38
    Chan Zuckerberg Initiative +2 othersJuly 9, 2025cell_type_annotationchromatinfoundation_model+6

    Single-cell transcriptomics foundation model that encodes gene regulatory network structure into self-attention through graph signal processing.

    Single-cell
    80Openness
  • MNCN-CSICJuly 9, 2025bertembeddingsfoundation_model+4

    Zebrafish single-cell foundation model built on the Geneformer framework, producing frozen gene and cell embeddings for developmental analysis.

    Single-cell
    46Openness
  • STATE

    623117250
    Arc InstituteJune 27, 2025drug_discoveryfoundation_modelgene_expression+4

    Virtual cell transformer that predicts how cells respond to genetic, chemical, or signaling perturbations, generalizing to unseen cellular contexts.

    Single-cell
    21Openness
  • MOJO

    4045
    InstaDeepJune 25, 2025bertdna_methylationfoundation_model+7

    Bimodal masked language model that jointly encodes bulk RNA-seq expression and DNA methylation into patient-level embeddings for cancer genomics.

    RNADNA & Gene
    29Openness