All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 51 filtered models
miDGD
———A deep generative decoder that infers microRNA expression directly from bulk or single-cell mRNA gene expression via a shared mRNA/miRNA latent space.
RNASingle-cell8OpennessTxFM
2——A self-supervised masked autoencoder for RNA-seq count data, pretrained on 1.4M public samples to learn transferable transcriptomic representations without per-dataset re-training.
Single-cell12OpennessChreode
———University of North Carolina at Chapel Hill +2 othersMay 27, 2026cell_fate_predictioncrispr_perturbationdevelopmental_trajectory_modeling+8A cell world model pretrained on a 2.4M-cell mouse embryonic atlas that predicts one-step transcriptional state transitions and transfers to perturbation prediction.
Single-cell26OpennessFlowTransOP
———A constrained deep flow-matching framework for distributional translation of omics signatures across biological domains, such as mouse-to-human transcriptomics, without paired samples.
Single-cell87OpennessConvergeCELL
——59A virtual cell foundation model pretrained on 23M+ cells from 5,000 patient samples for drug target and biomarker discovery.
Single-cell67OpennessscPert
———A multi-modal Transformer that fuses LLM gene embeddings with biological knowledge graphs to predict single-cell transcriptomic responses to genetic perturbations.
Single-cell14OpennessHyperMap
———Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few seed perturbations, using one-eighth the parameters of typical single-cell foundation models.
Single-cell11OpennessGenNA
———An autoregressive nucleotide-and-text foundation model pretrained on ~416B characters from 2,221 eukaryotic species for natural-language-guided conditional generation of DNA and RNA sequences.
DNA & GeneRNA16OpennessCellPulse
———A direction-aware foundation model trained on ~23M bulk RNA-seq differential-expression profiles that simulates coordinated gene dynamics in viral infection.
Single-cellLanguage model4OpennessRNABag
———HomiGen Intelligence Technology Co., Ltd.April 22, 2026cancer_detectioncell_type_annotationfoundation_model+6A transcriptome foundation model for precision oncology that generalizes zero-shot across tissue, plasma cfRNA, and tumor-educated platelet biopsy modalities.
Single-cell46OpennessxVERSE
———A transcriptomics-native single-cell foundation model that couples batch-invariant representation learning with probabilistic virtual-cell generation.
Single-cell10OpennessCLOP-DiT
———Generates single-cell transcriptomic profiles from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.
Single-cell10OpennessRNAGAN
1——Multipurpose generative adversarial network trained once on single-cell and bulk RNA-seq to perform stratification, marker analysis, data generation, and vectorization.
Single-cell60OpennessCellPace
———A temporal diffusion-forcing generative framework for simulating, interpolating, and forecasting single-cell developmental dynamics from irregularly sampled time-series data.
Single-cell9OpennessPerturbDiff
435—Functional diffusion model that predicts single-cell perturbation responses by generating over distributions embedded in a Hilbert space, capturing population-level response variability.
Single-cell51OpennessCellAwareGNN
———Vanderbilt University Medical CenterFebruary 23, 2026drug_discoveryfoundation_modelgraph_neural_network+4A knowledge-graph foundation model that injects cell-type-specific genetic associations into a biomedical knowledge graph to improve drug indication prediction and repurposing.
Single-cellSmall molecule11OpennessA discrete-diffusion generative model that operates directly on single-cell gene counts, enabling unconditional and perturbation-conditioned scRNA-seq generation.
Single-cell10OpennessevoCancerGPT
———A decoder-only single-cell foundation model that forecasts future single-cell gene expression in cancer evolution from prior cell states, generalizing zero-shot to held-out cancers.
Single-cell11OpennessEVA
——101Cross-species, multimodal foundation model of immunology and inflammation that harmonizes transcriptomics and histology into unified patient-level representations.
Single-cellRNAPathology27OpennessscDFM
395—Distributional flow matching model for single-cell perturbation prediction that models population-level expression shifts using a graph-aware differential-attention transformer.
Single-cell54OpennessPert2Mol
———A multimodal generative model that designs molecules from transcriptomic and morphological perturbation phenotypes using rectified flow transformers.
Small moleculeSingle-cell22OpennessscDiVa
———A masked discrete-diffusion single-cell foundation model that jointly generates cell identity and expression, pre-trained on 59 million cells.
Single-cell6OpennessLLM-based generative model that synthesizes complete single-cell RNA-seq profiles from tissue and disease metadata alone, treating cells as gene-expression token sequences.
Single-cellSpatial omics2OpennessOKR-CELL
———Cross-modal cell-language foundation model that aligns single-cell expression with LLM-enriched textual descriptions using a noise-robust contrastive objective.
Single-cellLanguage model23Openness