All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 51 filtered models

  • miDGD

    Aarhus UniversityJune 2, 2026autoencoderdeep_generative_decodergene_expression+6

    A deep generative decoder that infers microRNA expression directly from bulk or single-cell mRNA gene expression via a shared mRNA/miRNA latent space.

    RNASingle-cell
    8Openness
  • TxFM

    2
    Recursion PharmaceuticalsMay 31, 2026autoencoderfoundation_modelgene_expression+4

    A self-supervised masked autoencoder for RNA-seq count data, pretrained on 1.4M public samples to learn transferable transcriptomic representations without per-dataset re-training.

    Single-cell
    12Openness
  • Chreode

    University of North Carolina at Chapel Hill +2 othersMay 27, 2026cell_fate_predictioncrispr_perturbationdevelopmental_trajectory_modeling+8

    A cell world model pretrained on a 2.4M-cell mouse embryonic atlas that predicts one-step transcriptional state transitions and transfers to perturbation prediction.

    Single-cell
    26Openness
  • FlowTransOP

    MIT +2 othersMay 27, 2026autoencodercross_domain_translationcross_species+7

    A constrained deep flow-matching framework for distributional translation of omics signatures across biological domains, such as mouse-to-human transcriptomics, without paired samples.

    Single-cell
    87Openness
  • ConvergeCELL

    59
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    A virtual cell foundation model pretrained on 23M+ cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • scPert

    Zhejiang University School of MedicineApril 28, 2026drug_discoveryfoundation_modelgene_expression+4

    A multi-modal Transformer that fuses LLM gene embeddings with biological knowledge graphs to predict single-cell transcriptomic responses to genetic perturbations.

    Single-cell
    14Openness
  • HyperMap

    University of California San Diego +1 otherApril 27, 2026crisprdrug_discoveryfew_shot+7

    Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few seed perturbations, using one-eighth the parameters of typical single-cell foundation models.

    Single-cell
    11Openness
  • GenNA

    Zhejiang UniversityApril 24, 2026de_novo_designfoundation_modelgenerative+5

    An autoregressive nucleotide-and-text foundation model pretrained on ~416B characters from 2,221 eukaryotic species for natural-language-guided conditional generation of DNA and RNA sequences.

    DNA & GeneRNA
    16Openness
  • CellPulse

    Wuhan Institute of VirologyApril 24, 2026drug_discoveryfoundation_modelgene_expression+5

    A direction-aware foundation model trained on ~23M bulk RNA-seq differential-expression profiles that simulates coordinated gene dynamics in viral infection.

    Single-cellLanguage model
    4Openness
  • RNABag

    HomiGen Intelligence Technology Co., Ltd.April 22, 2026cancer_detectioncell_type_annotationfoundation_model+6

    A transcriptome foundation model for precision oncology that generalizes zero-shot across tissue, plasma cfRNA, and tumor-educated platelet biopsy modalities.

    Single-cell
    46Openness
  • xVERSE

    Duke UniversityApril 14, 2026batch_effect_correctionfoundation_modelgenerative+5

    A transcriptomics-native single-cell foundation model that couples batch-invariant representation learning with probabilistic virtual-cell generation.

    Single-cell
    10Openness
  • CLOP-DiT

    Third Military Medical UniversityMarch 30, 2026contrastive_learningdata_augmentationdiffusion+7

    Generates single-cell transcriptomic profiles from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.

    Single-cell
    10Openness
  • RNAGAN

    1
    The University of Hong KongMarch 20, 2026cancercell_type_annotationdata_generation+5

    Multipurpose generative adversarial network trained once on single-cell and bulk RNA-seq to perform stratification, marker analysis, data generation, and vectorization.

    Single-cell
    60Openness
  • CellPace

    McGill UniversityFebruary 26, 2026cell_biologydiffusiongene_expression+5

    A temporal diffusion-forcing generative framework for simulating, interpolating, and forecasting single-cell developmental dynamics from irregularly sampled time-series data.

    Single-cell
    9Openness
  • MilaFebruary 23, 2026diffusiongene_expressiongenerative+3

    Functional diffusion model that predicts single-cell perturbation responses by generating over distributions embedded in a Hilbert space, capturing population-level response variability.

    Single-cell
    51Openness
  • CellAwareGNN

    Vanderbilt University Medical CenterFebruary 23, 2026drug_discoveryfoundation_modelgraph_neural_network+4

    A knowledge-graph foundation model that injects cell-type-specific genetic associations into a biomedical knowledge graph to improve drug indication prediction and repurposing.

    Single-cellSmall molecule
    11Openness
  • University of BristolFebruary 19, 2026data_generationdiffusionfoundation_model+4

    A discrete-diffusion generative model that operates directly on single-cell gene counts, enabling unconditional and perturbation-conditioned scRNA-seq generation.

    Single-cell
    10Openness
  • evoCancerGPT

    Dana-Farber Cancer InstituteFebruary 14, 2026cancerfoundation_modelgene_expression+5

    A decoder-only single-cell foundation model that forecasts future single-cell gene expression in cancer evolution from prior cell states, generalizing zero-shot to held-out cancers.

    Single-cell
    11Openness
  • EVA

    101
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species, multimodal foundation model of immunology and inflammation that harmonizes transcriptomics and histology into unified patient-level representations.

    Single-cellRNAPathology
    27Openness
  • scDFM

    395
    Westlake UniversityFebruary 6, 2026flow_matchinggene_expressiongenerative+4

    Distributional flow matching model for single-cell perturbation prediction that models population-level expression shifts using a graph-aware differential-attention transformer.

    Single-cell
    54Openness
  • Pert2Mol

    Purdue UniversityFebruary 4, 2026de_novo_designgenerativemolecular_generation+5

    A multimodal generative model that designs molecules from transcriptomic and morphological perturbation phenotypes using rectified flow transformers.

    Small moleculeSingle-cell
    22Openness
  • scDiVa

    Renmin University of ChinaFebruary 3, 2026batch_integrationcell_type_annotationdiffusion+6

    A masked discrete-diffusion single-cell foundation model that jointly generates cell identity and expression, pre-trained on 59 million cells.

    Single-cell
    6Openness
  • Seoul National University HospitalJanuary 12, 2026cancercell_type_annotationdata_generation+6

    LLM-based generative model that synthesizes complete single-cell RNA-seq profiles from tissue and disease metadata alone, treating cells as gene-expression token sequences.

    Single-cellSpatial omics
    2Openness
  • OKR-CELL

    BGI ResearchJanuary 9, 2026batch_effect_correctioncell_biologycell_clustering+7

    Cross-modal cell-language foundation model that aligns single-cell expression with LLM-enriched textual descriptions using a noise-robust contrastive objective.

    Single-cellLanguage model
    23Openness