All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 111 of 11 filtered models

  • ProteinSage

    BioMapMarch 19, 2026foundation_modelprotein_structurerepresentation_learning+3

    Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.

    Protein
    12Openness
  • RigidSSL

    19183
    Chinese University of Hong KongMarch 2, 2026conformational_ensemble_generationflow_matchinggenerative+5

    Self-supervised SE(3) geometric pretraining for protein backbone generators, improving designability, motif scaffolding, and conformational ensembles.

    Protein
    73Openness
  • CaltechFebruary 6, 2026autoencoderprotein_designprotein_structure+4

    Protein structure tokenizer that encodes a whole structure globally, with each successive token adding detail for adaptive-length representations.

    Protein
    6Openness
  • ProteinEBM

    7
    MITDecember 9, 2025conformational_dynamicsconformational_samplingdiffusion+5

    Energy-based model of protein conformational space, turning a diffusion model into a statistical potential for structure ranking and mutation scoring.

    Protein
    8Openness
  • ConforFold

    Washington University in St. LouisOctober 14, 2025conformational_samplingprotein_structurestructure_prediction+2

    Protein conformational sampling framework that steers a retrained OpenFold with diverse secondary-structure predictions to recover alternative states.

    Protein
    45Openness
  • ProteinAE

    214
    Chinese University of Hong Kong +2 othersOctober 12, 2025autoencoderde_novo_designdiffusion+5

    Protein structure autoencoder compressing backbone coordinates into a latent space, paired with a latent diffusion model for generative design.

    Protein
    74Openness
  • FlexRibbon

    2
    Beijing Zhongguancun AcademyOctober 10, 2025diffusionfoundation_modelmultimodal+5

    Protein foundation model with 3B parameters, pretrained jointly on sequence and 3D structure via masked language modeling and diffusion denoising.

    Protein
    20Openness
  • DiffTopo

    EPFLOctober 10, 2025de_novo_designdiffusiongenerative+3

    Diffusion model over coarse-grained protein topology that samples diverse folds, handing them to RFdiffusion to build de novo protein backbones.

    Protein
    20Openness
  • Kanzi

    3832
    CaltechOctober 3, 2025autoencoderflow_matchinggenerative+4

    Flow-based protein structure tokenizer, a diffusion autoencoder replacing SE(3)-invariant components with global coordinates and standard attention.

    Protein
    63Openness
  • GCP-VQVAE

    432
    University of MissouriOctober 1, 2025graph_neural_networkprotein_structurerepresentation_learning+4

    Protein structure tokenizer that maps 3D backbones to discrete tokens with an SE(3)-equivariant encoder preserving orientation and chirality.

    Protein
    86Openness
  • CLASP

    44
    McGill UniversityAugust 10, 2025contrastive_learningcross_modal_retrievalgraph_neural_network+7

    Tri-modal contrastive model aligning protein structure, sequence, and text in a shared space for zero-shot cross-modal retrieval and classification.

    Protein
    42Openness