All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 13 of 3 filtered models

  • DBMol

    EPFL +2 othersJuly 21, 2026de_novo_designdrug_discoveryflow_matching+4

    De novo small molecule design for protein pockets, steering a discrete flow-matching generator with gradients from a frozen Boltz-2 affinity model.

    Small moleculeProtein
    21Openness
  • FlexiFlow

    1
    AstraZeneca +4 othersNovember 21, 2025conformer_generationde_novo_designdrug_discovery+7

    Flow-matching model that jointly samples 3D de novo molecules and several low-energy conformers, extending to pocket-conditioned ligand design.

    Small moleculeProtein
    19Openness
  • Apo2Mol

    38
    University of FloridaNovember 18, 2025binding_pocketde_novo_designdiffusion+5

    Diffusion model for structure-based drug design that jointly generates 3D ligands and holo pocket conformations from an apo protein structure.

    Small moleculeProtein
    65Openness