All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 17 of 7 filtered models

  • Chamaileon

    1217
    Zhejiang UniversityJuly 26, 2026de_novo_designflow_matchinggenerative+2

    Cross-context protein binder design model that generates one sequence binding multiple targets or conformational states of the same target.

    Protein
    66Openness
  • MoE-Bind

    2
    University of North BengalJune 13, 2026autoregressivede_novo_designgenerative+6

    Protein binder generator producing receptor-conditioned binders from sequence alone, using a sparse Mixture-of-Experts transformer with no 3D input.

    Protein
    54Openness
  • NVIDIAMarch 16, 2026all_atomde_novo_designflow_matching+6

    Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.

    Protein
    68Openness
  • Tsinghua UniversityFebruary 13, 2026de_novo_designdiffusionequivariant_neural_network+4

    Latent diffusion model that designs D-peptide binders against native L-protein targets, generalizing across chirality via axial vector features.

    Protein
    67Openness
  • PPIFlow

    4
    Changping LaboratoryJanuary 22, 2026antibodyde_novo_designflow_matching+5

    Flow-matching generative model for de novo protein binder backbone design, built on a Pairformer architecture with in silico interface maturation.

    Protein
    4Openness
  • Macao Polytechnic UniversityJanuary 12, 2026peptide_designprotein_binder_designde_novo_design+6

    Sequence-only latent diffusion model that designs target-specific peptide binders, cascaded with an affinity classifier through joint optimization.

    ProteinSmall molecule
    4Openness
  • HighPlay

    1110
    Macao Polytechnic University +3 othersMarch 17, 2025de_novo_designgenerativepeptide_design+4

    Cyclic peptide binder design by Monte Carlo tree search over sequence space, scored by predicted confidence of the peptide-target complex fold.

    Protein
    47Openness