All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–12 of 12 filtered models
MethylSeqNet
———University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.
DNA & Gene18OpennessTransformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.
DNA & Gene10OpennessISTS
———Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.
Single-cellDNA & Gene20OpennessMelody
———Deep learning framework that predicts DNA methylation from genomic sequence across 39 human tissues, with an scRNA-seq variant for unseen cell types.
DNA & Gene8OpennessscDNAm-GPT
202—Guangzhou Medical University +1 otherFebruary 23, 2025cell_type_annotationcross_attentiondna_methylation+5Single-cell DNA methylation foundation model capturing genome-wide CpG dependencies in whole-genome bisulfite sequencing across tissues and species.
Single-cellDNA & Gene78OpennessMuLan-Methyl
7105Multi-language transformer framework using five pre-trained language models to predict DNA methylation (6mA, 4mC, 5hmC) across species.
DNA & Gene89OpennessmEthAE
34—Chromosome-wise explainable autoencoder that compresses DNA methylation array data up to 400-fold while keeping CpG groupings interpretable.
DNA & Gene47OpennessiDNA-ABF
15141—DNA language model for interpretable prediction of 4mC, 5hmC, and 6mA methylation sites across species, using multi-scale k-mer BERT encoders.
DNA & Gene53OpennessINTERACT
1125—Lieber Institute for Brain DevelopmentAugust 16, 2022deep_learningdna_methylationepigenomic_prediction+4Deep learning model predicting DNA methylation regulatory variants at CpG sites in the human brain, fine-mapping psychiatric disorder risk loci.
DNA & Gene9OpennessBERT6mA
516—BERT-based predictor of DNA N6-methyladenine (6mA) modification sites, using word2vec encoding and cross-species transfer learning.
DNA & Gene45OpennessCpG Transformer
3921—Transformer that imputes missing CpG methylation states from sparse single-cell bisulfite sequencing, modeling genomic and cell-level structure.
DNA & Gene79Openness