All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–13 of 13 filtered models
RNAJog
2——Autoregressive generative model that uses reinforcement learning to optimize mRNA codon sequences for MFE, CAI, and GC content.
RNA9OpennessRNARL
———Shanghai Jiao Tong University +2 othersJune 13, 2026codon_optimizationrna_designsequence_generation+7Reinforcement-learning generative framework for multi-objective RNA codon optimization that generalizes across six species and five RNA types.
RNA4OpennessmRNA-GPT
42—Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.
RNA10OpennessPro2RNA
———Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.
RNAProtein10OpennessmRNA-GPT
41—GPT-style generative language model for mRNA coding sequences, pretrained across bacteria, eukaryotes, and archaea for de novo CDS design.
RNA39Openness- University of Maryland, College ParkNovember 24, 2025codon_optimizationde_novo_designfoundation_model+6
Conditional codon language model with 150M parameters that generates species-optimized coding sequences from a protein and its taxonomic lineage.
DNA & GeneRNA90Openness SynCodonLM
6—53Codon language model trained with synonymous-codon-constrained masking, so its embeddings encode nucleotide-level signal, not amino acid identity.
DNA & GeneRNA98OpennessTransCodon
3——Shenzhen Institutes of Advanced Technology, CAS +5 othersJuly 19, 2025codon_optimizationdnalanguage_model+1Species-conditioned codon language model that jointly reads 5'UTRs, coding sequence, and RNA secondary structure to design native-like genes.
RNADNA & Gene23OpennesscodonGPT
—391Generative codon language model for mRNA design, trained on 338,417 coding sequences with inference-time masking that preserves the encoded protein.
RNADNA & Gene16OpennessHigh-Codon
—2—Codon optimization model for heterologous expression in E. coli, fine-tuning ProtBert to label each residue with an expression-weighted codon.
DNA & GeneProtein12OpennessRNop
77—mRNA optimization model that raises codon adaptation, tRNA adaptation, and folding stability at once while preserving the encoded protein sequence.
RNA65OpennessTrias
135471Encoder-decoder codon language model that reverse-translates a protein into species-specific coding sequences for synthetic mRNA design.
RNAProtein85OpennessppLM-CO
———Codon optimization framework that adds a generative head to a frozen ProtBert protein language model to design highly expressed coding sequences.
RNAProtein12Openness