All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 26 filtered models
TifBERT
2——Bulk RNA-seq foundation model learning normalization-robust transcriptome representations via TF-IDF gene ordering and masked gene modeling.
RNA17OpennessPepForge
4——Generative model for chemically modified and macrocyclic peptides that builds molecules in HELM notation, supporting de novo design and infilling.
ProteinSmall molecule94OpennessDamageFormer
1——Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.
DNA & Gene45Openness110M-parameter RNA language model that designs sequences from secondary structure, motif, and Gene Ontology constraints via discrete diffusion.
RNA48OpennessPeptideCLM-2
102—Chemical language models pretrained on SMILES for therapeutic peptides, natively representing non-canonical residues, cyclization, and conjugation.
Small moleculeProtein79OpennessOncoBERT
———BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.
DNA & Gene7OpennessNUWA
———mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.
RNADNA & Gene16OpennessMetagenBERT
———Annotation-free metagenome embedding pipeline that encodes raw DNA reads with genomic language models and pools them via FAISS k-means clustering.
DNA & Gene22OpennessISTS
———Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.
Single-cellDNA & Gene20OpennessH3BERTa
1—201Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.
ProteinLanguage model83OpennessNyxBind
1—2Hong Kong University of Science and TechnologyOctober 21, 2025bertbinding_site_predictioncontrastive_learning+5Transcription factor binding site prediction model that refines a DNABERT-2 backbone with contrastive learning across diverse TFBS types.
DNA & Gene40OpennessstructRFM
36329RNA foundation model pretrained jointly on sequences and secondary structures for structure prediction, homology and splice site classification.
RNA92OpennessZebraformer
—1—Zebrafish single-cell foundation model built on the Geneformer framework, producing frozen gene and cell embeddings for developmental analysis.
Single-cell46OpennessseqLens
7——Genomic language models with disentangled attention, pretrained on prokaryotic and eukaryotic genomes for sequence classification and variant effects.
DNA & Gene18OpennessChromatin-state language model pretrained on ROADMAP annotations from 127 human cell types to find chromatin-state motifs and predict gene expression.
DNA & Gene86OpennessMammo-CLIP
98—45Vision-language foundation model pre-trained on screening mammogram-report pairs to improve data efficiency and robustness in breast cancer detection.
ImagingPathology27OpennessCaLM
5445—Codon-level BERT model that captures genomic signals invisible to amino acid models, outperforming billion-parameter PLMs with just 86M parameters.
Protein66OpennessCXR-CLIP
123138—Large-scale chest X-ray vision-language pretraining model that learns image-report alignment for zero-shot and few-shot radiograph classification.
Imaging18OpennessSpecies-Aware DNA LM
29538.1KMasked DNA language model trained on over 800 vertebrate genomes and conditioned on species identity to learn conserved regulatory sequence features.
DNA & Gene76Openness