All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 121–144 of 518 filtered models
muat
8——Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.
DNA & Gene65OpennessmRNA-GPT
42—Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.
RNA10OpennessscLong
2210—Billion-parameter single-cell foundation model with self-attention over 28,000 human genes, adding Gene Ontology priors via a graph neural network.
Single-cell29OpennessDiscrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.
DNA & Gene49OpennessEnzyGen2
30——Protein foundation model for de novo enzyme design that co-designs sequence and 3D structure under small-molecule ligand guidance, at 730M parameters.
ProteinSmall molecule89OpennessCLOP-DiT
———Generates single-cell transcriptomes from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.
Single-cell10OpennessEEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.
Biosignals18OpennessIDPForge
162—Chinese Academy of SciencesMarch 25, 2026conformational_ensembleconformational_ensemble_generationdiffusion+7Protein-language diffusion model generating all-atom conformational ensembles for intrinsically disordered proteins and disordered regions.
Protein29OpennessEVA
821—Generative RNA foundation model trained on 114 million full-length sequences for de novo design of tRNAs, aptamers, CRISPR guide RNAs, and mRNAs.
RNA72OpennessZeroFold
———University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.
RNAProtein23OpennessProAR
———Autoregressive generative model for protein molecular dynamics that emits flexible-length trajectories frame by frame with anti-drifting sampling.
Protein19OpennessBioReason-Pro
1229—Multimodal reasoning LLM for protein function prediction, fusing protein language model embeddings to emit interpretable GO-term reasoning traces.
ProteinLanguage model58OpennessCLIPepPI
2——Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.
Protein50OpennessGO-GPT
122939Protein function prediction model that autoregressively generates Gene Ontology terms from amino acid sequence instead of classifying fixed labels.
Protein55OpennessProteinSage
———Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.
Protein12OpennessSELFormerMM
3——Multimodal molecular foundation model fusing SELFIES, 2D graphs, text, and knowledge graphs via contrastive pretraining for property prediction.
Small molecule55OpennessPro2RNA
———Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.
RNAProtein10OpennessRNAElectra
———Single-nucleotide-resolution RNA foundation model pretrained on non-coding RNAs with ELECTRA-style replaced-token detection for regulatory inference.
RNA23OpennessSCALE
———Virtual cell foundation model predicting single-cell responses to genetic, chemical, and cytokine perturbations with conditional flow matching.
Single-cell19OpennessHERCULES
———Protein language model that classifies RNA-binding proteins, localizes RNA-binding domains, and scores mutation effects at single-residue resolution.
Protein44OpennessHorizyn-1
123—Dual-encoder contrastive model that retrieves enzymes for query reactions by matching reaction fingerprints to protein sequence embeddings.
ProteinSmall molecule21OpennessX-Cell
1068—Diffusion language model with 4.9 billion parameters that predicts genome-wide CRISPRi perturbation responses in single-cell transcriptomes.
Single-cell20OpennessAI-IDP
———German Center for Neurodegenerative Diseases (DZNE)March 16, 2026conformational_ensemble_generationintrinsically_disordered_proteinsproteomics+3Sequence-to-ensemble predictor that generates conformational ensembles of intrinsically disordered proteins zero-shot, with no per-sequence refitting.
Protein4OpennessProteina-Complexa
39821148Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.
Protein68Openness