All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 121144 of 518 filtered models

  • muat

    8
    University of HelsinkiApril 3, 2026attentioncancer_genomicsrepresentation_learning+5

    Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.

    DNA & Gene
    65Openness
  • Chinese Academy of SciencesApril 2, 2026codoncodon_optimizationfoundation_model+8

    Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.

    RNA
    10Openness
  • scLong

    2210
    Chinese Academy of SciencesApril 1, 2026batch_integrationcell_type_annotationfoundation_model+5

    Billion-parameter single-cell foundation model with self-attention over 28,000 human genes, adding Gene Ontology priors via a graph neural network.

    Single-cell
    29Openness
  • Cold Spring Harbor LaboratoryApril 1, 2026de_novo_designdiffusiongene_expression+5

    Discrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.

    DNA & Gene
    49Openness
  • EnzyGen2

    30
    Carnegie Mellon UniversityMarch 31, 2026de_novo_designenzyme_designfoundation_model+5

    Protein foundation model for de novo enzyme design that co-designs sequence and 3D structure under small-molecule ligand guidance, at 730M parameters.

    ProteinSmall molecule
    89Openness
  • CLOP-DiT

    Third Military Medical UniversityMarch 30, 2026contrastive_learningdata_augmentationdiffusion+7

    Generates single-cell transcriptomes from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.

    Single-cell
    10Openness
  • Carnegie Mellon UniversityMarch 27, 2026brain_computer_interfaceeegfoundation_model+5

    EEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.

    Biosignals
    18Openness
  • IDPForge

    162
    Chinese Academy of SciencesMarch 25, 2026conformational_ensembleconformational_ensemble_generationdiffusion+7

    Protein-language diffusion model generating all-atom conformational ensembles for intrinsically disordered proteins and disordered regions.

    Protein
    29Openness
  • EVA

    821
    GENTEL LabMarch 24, 2026aptameraptamer_designcircular_rna+9

    Generative RNA foundation model trained on 114 million full-length sequences for de novo design of tRNAs, aptamers, CRISPR guide RNAs, and mRNAs.

    RNA
    72Openness
  • ZeroFold

    University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3

    Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.

    RNAProtein
    23Openness
  • ProAR

    Peking UniversityMarch 21, 2026autoregressiveconformational_samplinggenerative+4

    Autoregressive generative model for protein molecular dynamics that emits flexible-length trajectories frame by frame with anti-drifting sampling.

    Protein
    19Openness
  • Arc Institute +3 othersMarch 20, 2026go_term_annotationlarge_language_modelmultimodal+5

    Multimodal reasoning LLM for protein function prediction, fusing protein language model embeddings to emit interpretable GO-term reasoning traces.

    ProteinLanguage model
    58Openness
  • CLIPepPI

    2
    Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5

    Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.

    Protein
    50Openness
  • GO-GPT

    122939
    Bowang LabMarch 20, 2026gene_ontologygenerativego_term_annotation+3

    Protein function prediction model that autoregressively generates Gene Ontology terms from amino acid sequence instead of classifying fixed labels.

    Protein
    55Openness
  • ProteinSage

    BioMapMarch 19, 2026foundation_modelprotein_structurerepresentation_learning+3

    Structure-aware protein language model using structure-guided masking and a causal objective for variant effect prediction and protein discovery.

    Protein
    12Openness
  • Hacettepe UniversityMarch 19, 2026cheminformaticscontrastive_learningdrug_discovery+5

    Multimodal molecular foundation model fusing SELFIES, 2D graphs, text, and knowledge graphs via contrastive pretraining for property prediction.

    Small molecule
    55Openness
  • Pro2RNA

    Kitasato UniversityMarch 18, 2026codon_optimizationcodon_usagelanguage_model+5

    Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.

    RNAProtein
    10Openness
  • RNAElectra

    Australian National UniversityMarch 17, 2026foundation_modelself_supervisedstructure_prediction+1

    Single-nucleotide-resolution RNA foundation model pretrained on non-coding RNAs with ELECTRA-style replaced-token detection for regulatory inference.

    RNA
    23Openness
  • SCALE

    Shanghai AI LaboratoryMarch 17, 2026flow_matchingfoundation_modelgenerative+4

    Virtual cell foundation model predicting single-cell responses to genetic, chemical, and cytokine perturbations with conditional flow matching.

    Single-cell
    19Openness
  • HERCULES

    Italian Institute of TechnologyMarch 17, 2026multi_taskproteomicsrna_binding_prediction+4

    Protein language model that classifies RNA-binding proteins, localizes RNA-binding domains, and scores mutation effects at single-residue resolution.

    Protein
    44Openness
  • Horizyn-1

    123
    Dayhoff LabsMarch 17, 2026contrastive_learningenzyme_reaction_matchingenzymology+5

    Dual-encoder contrastive model that retrieves enzymes for query reactions by matching reaction fingerprints to protein sequence embeddings.

    ProteinSmall molecule
    21Openness
  • X-Cell

    1068
    Xaira TherapeuticsMarch 17, 2026crispr_perturbationdiffusionfoundation_model+4

    Diffusion language model with 4.9 billion parameters that predicts genome-wide CRISPRi perturbation responses in single-cell transcriptomes.

    Single-cell
    20Openness
  • AI-IDP

    German Center for Neurodegenerative Diseases (DZNE)March 16, 2026conformational_ensemble_generationintrinsically_disordered_proteinsproteomics+3

    Sequence-to-ensemble predictor that generates conformational ensembles of intrinsically disordered proteins zero-shot, with no per-sequence refitting.

    Protein
    4Openness
  • NVIDIAMarch 16, 2026all_atomde_novo_designflow_matching+6

    Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.

    Protein
    68Openness