All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 73–96 of 209 filtered models
HD-Prot
74—Multimodal protein language model that adds a continuous-token diffusion head to a discrete pLM, modeling structure without vector quantization.
Protein14OpennessM-Optimus
———Multimodal foundation model that embeds histology, transcriptomics, and clinical records in one space for patient stratification and target discovery.
PathologySpatial omicsSingle-cell3OpennessEXAONE Path 2.5
5280Pathology foundation model that aligns whole-slide images with genomic, epigenetic, and transcriptomic data for patient-level tumor representations.
PathologySpatial omics14OpennessEva
—4—Enable Medicine +4 othersDecember 12, 2025cell_type_annotationcross_modal_inferencefoundation_model+8Tissue imaging foundation model pretrained on matched H&E histology and spatial proteomics for cross-modal inference and zero-shot retrieval.
PathologySpatial omics4OpennessISTS
———Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.
Single-cellDNA & Gene20OpennessFusionProt
183—Technion – Israel Institute of Technology +1 otherNovember 26, 2025function_predictiongraph_neural_networkmultimodal+4Multimodal protein representation model that iteratively fuses a sequence language model with a 3D structure encoder through a shared learnable token.
Protein68OpennessMelody
———Deep learning framework that predicts DNA methylation from genomic sequence across 39 human tissues, with an scRNA-seq variant for unseen cell types.
DNA & Gene8OpennessNeuroVFM
554654University of Michigan +1 otherNovember 23, 2025ctfoundation_modeljoint_embedding_predictive_architecture+8Generalist neuroimaging vision foundation model pretrained on 5.24M clinical MRI and CT volumes for radiologic diagnosis and report generation.
Imaging57OpennessPuget
———Gene expression prediction model combining DNA sequence with Hi-C contact maps to capture 3D chromatin looping behind cell-type-specific expression.
DNA & Gene8OpennessEvo2HiC
102—University of WashingtonNovember 19, 2025chromatinchromatin_contact_predictionepigenomic_profiling+9Multimodal foundation model that distills Evo 2 into a compact encoder guided by Hi-C data, predicting cell-type-specific 3D genome architecture.
DNA & GeneSpatial omics57OpennessSIGMMA
—1—Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.
PathologySpatial omics20OpennessUni-Hema
—1—Information Technology University of the Punjab +1 otherNovember 18, 2025classificationcnnfoundation_model+8Digital hematopathology foundation model unifying blood-cell detection, classification, segmentation, and visual question answering.
Pathology8OpennessMultimodal conversational LLM for metabolite analysis, fusing a molecular-graph GNN and molecular-image CNN with a Vicuna-13B language backbone.
MetabolomicsSmall molecule48OpennessMolChord
—2—Structure-based drug design model that generates ligands for a protein pocket, pairing a diffusion structure encoder with preference optimization.
Small moleculeProtein23OpennessOpenFold3
7961—Open-source Apache-2.0 reproduction of AlphaFold3 that predicts all-atom structures of proteins, RNA, DNA, small molecules, and their complexes.
ProteinRNASmall molecule92Openness- Verily Life SciencesOctober 24, 2025cross_attentiondisease_risk_predictionelectronic_health_records+7
Multimodal EHR foundation model that fuses polygenic risk scores into a GPT-2-style backbone by cross-attention for zero-shot disease risk prediction.
Language modelDNA & Gene8Openness Tahoe-x1
1591539Perturbation-trained single-cell foundation models (up to 3B parameters) that jointly model genes, cells, and compounds for precision oncology tasks.
Single-cellSmall molecule95OpennessMetaboFM
—2—Georgia Institute of TechnologyOctober 23, 2025classificationfoundation_modelmass_spectrometry_imaging+6Vision Transformer foundation model for spatial metabolomics, pretrained on ~4,000 curated METASPACE mass spectrometry imaging datasets.
MetabolomicsSpatial omicsImaging10OpennessCellTok
———Multimodal LLM that tokenizes single cells into discrete VQ-VAE codebook tokens, letting one model reason jointly over transcriptomes and text.
Single-cellLanguage model20OpennessKnowMol
95—Institute of Computing Technology, Chinese Academy of SciencesOctober 22, 2025cheminformaticsde_novo_designgraph_neural_network+6Multimodal molecular large language model grounding molecule understanding and generation in fine-grained, multi-level chemical knowledge.
Small moleculeLanguage model69OpennessCoLiPRI
—155.5KVision-language encoders for chest CT that align 3D volumes with radiology reports using contrastive, report-generation, and masked-image objectives.
Imaging60OpennessMIMO
1227—Medical vision-language model that takes visual prompts on an image and returns answers grounded in pixel-level segmentation masks.
ImagingLanguage model11Openness