All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 209 filtered models
MolSight
———Renmin University of ChinaJuly 2, 2026graph_neural_networkmultimodaloptical_chemical_structure_recognition+2Vision-language model that reads molecular structure images, translating them to SMILES, captions, and properties via chemical-bond topology.
Small moleculeLanguage model21OpennessProLoc
———Text-guided localization model that grounds natural-language functional descriptions to specific residue regions of a protein sequence.
ProteinLanguage model10OpennesseRNAformer
2——Enhancer RNA mapping model that locates eRNA loci genome-wide from DNA sequence and aggregated RNA-seq signal using a CNN-transformer architecture.
DNA & GeneRNA95OpennessPertOmni
—1—Contrastive multimodal model for perturbation screens, aligning transcriptomic signatures with text and cell-painting image embeddings.
Single-cellSmall molecule18OpennessMolexar
7—17Multimodal molecular generation model for drug design, conditioned on properties, pharmacophores, protein sequences, or protein binding pockets.
Small moleculeProtein82OpennessSelf-supervised 3D masked autoencoder for volumetric fluorescence microscopy, aligned to ESM2 embeddings to predict protein localization.
ImagingSingle-cell71OpennessBioMatrix
41—167Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.
ProteinSmall moleculeLanguage model67OpennessvBx-1.0
———Multimodal foundation model for precision neurology that reconstructs a patient's molecular brain state from blood to predict disease progression.
Single-cellDNA & Gene5OpennessRepGene
———Gene representation framework fusing DNA, transcript, protein, text, and single-cell embeddings into one latent space that survives missing views.
DNA & GeneProteinSingle-cell22OpennessOmnii
———Genomic language model from Radical Numerics with a 2 Mbp context window, built for zero-shot variant effect prediction and sequence design.
DNA & Gene5OpennessRDiffusion
———Diffusion-based generative RNA model for de novo sequence design, conditioned on function, RNA family, structure, or binding proteins.
RNA5OpennessSpineAgent
6——Multi-sequence spine MRI foundation model with DINOv3 encoders, supporting condition classification, pathology localization, and report generation.
Imaging55OpennessChai-3
———Generative foundation model for antibody and multispecific design, doubling its predecessor's experimental success rate on therapeutic targets.
Protein4OpennessSQUALL
———Multimodal foundation model pretrained on 1.76B histology and spatial transcriptomics spots, inferring molecular state from whole-slide images.
PathologySpatial omics6OpennessVermeer
3——Generative microscopy foundation model that synthesizes in-silico fluorescence images of protein subcellular localization from amino-acid sequence.
ImagingProtein17OpennessAMix-2
———Protein-text foundation model placing amino acid sequences and natural language in one token space for protein understanding and de novo design.
ProteinLanguage model10OpennessSciCore-Omics
10—69Tri-modal foundation model unifying histology images, spatial transcriptomics, and language for zero-shot pathology and spatial biology reasoning.
PathologySpatial omics65OpennessSTMDiT
———Diffusion transformer for virtual tissue synthesis, generating H&E histopathology patches conditioned on spatial gene expression and morphology.
PathologySpatial omics44OpennessDamageFormer
1——Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.
DNA & Gene45OpennessBio-BLIP
———Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.
DNA & GeneLanguage model23OpennessProtLiD
6——370M-parameter ligand-conditioned discrete diffusion model that co-designs protein sequence and structure under explicit small-molecule constraints.
Protein5OpennessSpaRank
———Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.
Spatial omics8Openness