All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 163 filtered models
SQUALL
———Multimodal foundation model pretrained on 1.76 billion paired histology-spatial transcriptomics spots, linking whole-slide images to spatial molecular programs.
PathologySpatial omics6OpennessmiDGD
———A deep generative decoder that infers microRNA expression directly from bulk or single-cell mRNA gene expression via a shared mRNA/miRNA latent space.
RNASingle-cell8OpennessVermeer
2——Channel-adaptive autoregressive generative model that synthesizes in-silico fluorescence microscopy of protein subcellular localization from amino-acid sequence and cellular landmark stains.
ImagingProtein17OpennessAMix-2
———A protein-text foundation model embedding sequences and natural language in a shared token space, enabling protein understanding and de novo design from one checkpoint.
ProteinLanguage model10OpennessSciCore-Omics
8—238A tri-modal foundation model unifying histology images, spatial transcriptomics, and biological language for zero-shot spatial biology and pathology reasoning.
PathologySpatial omics65OpennessSTMDiT
———A diffusion transformer that synthesizes H&E histopathology image patches conditioned jointly on spatial transcriptomics gene expression and morphological embeddings.
PathologySpatial omics44OpennessDamageFormer
1——Multimodal deep-learning framework that detects and localizes DNA lesions directly from native nanopore sequencing, built on the damage-aware LesionBERT foundation model.
DNA & Gene45OpennessBio-BLIP
———A multimodal Q-former that fuses DNA sequence, gene context, protein function, and text into a prefix for a frozen LLM, enabling zero-shot genetic variant interpretation.
DNA & GeneLanguage model23OpennessProtLiD
4——A ligand-conditioned masked discrete diffusion model that co-designs protein sequence and structure under explicit small-molecule constraints.
Protein5OpennessSpaRank
———A transferable spatial-transcriptomics deconvolution model whose rank-based spot encoding lets one pretrained model generalize across tissues, disease states, and platforms without retraining.
Spatial omics8OpennessOmniGene-4
———A unified bio-language Mixture-of-Experts foundation model spanning DNA, protein sequence and structure, and biological text, applied across eight task families from a single checkpoint.
Language modelDNA & GeneProtein7OpennessBRIDGE
———The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8A multi-organ foundation model aligning histology image features with spatial-transcriptomics gene expression across 13 organs for zero-shot virtual ST and survival prediction.
PathologySpatial omics31OpennessA-CODE
———A fully atomic protein co-design model using unified multimodal diffusion to jointly refine atom types and coordinates in a single stage, with support for non-canonical amino acids.
Protein8OpennessDoFormer
———A causal multimodal Transformer that embeds the do-operator within attention to predict single-cell responses to gene perturbations, including unseen ones.
Single-cell8Openness- University of KentuckyMay 4, 2026contrastive_learningintrinsic_disorder_predictionmolecular_dynamics+6
A protein language model that aligns ESM sequence embeddings with molecular-dynamics trajectory embeddings via contrastive learning for zero-shot mutation-effect prediction.
Protein10Openness Proteo-R1
492115A reasoning-guided foundation model for de novo antibody CDR design, pairing a multimodal-LLM understanding expert with a Boltz-1-based diffusion generation expert.
Protein53OpennessscPert
———A multi-modal Transformer that fuses LLM gene embeddings with biological knowledge graphs to predict single-cell transcriptomic responses to genetic perturbations.
Single-cell14OpennessMIMIC
30——Generative multimodal foundation model that jointly models DNA, RNA, protein, and cellular context across six biological modalities, with SOTA splicing prediction.
RNAProteinDNA & Gene16OpennessGenNA
———An autoregressive nucleotide-and-text foundation model pretrained on ~416B characters from 2,221 eukaryotic species for natural-language-guided conditional generation of DNA and RNA sequences.
DNA & GeneRNA16OpennessH2O
———Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6A foundation model that predicts spatial transcriptomics and proteomics directly from routine H&E whole-slide images using a vision transformer aligned with a language model.
PathologySpatial omics7OpennessA 110M-parameter multimodal RNA language model that designs RNA sequences from secondary structure, consensus, and Gene Ontology constraints via discrete diffusion.
RNA48OpennessRVQ-Alpha
———A Qwen3-4B language model that reads and reasons over single cells by tokenizing scRNA-seq with residual vector quantization and training with verifiable reinforcement learning.
Single-cell4Openness