All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 209 filtered models

  • MolSight

    Renmin University of ChinaJuly 2, 2026graph_neural_networkmultimodaloptical_chemical_structure_recognition+2

    Vision-language model that reads molecular structure images, translating them to SMILES, captions, and properties via chemical-bond topology.

    Small moleculeLanguage model
    21Openness
  • Canopy

    Twig BioJuly 1, 2026enzymesfoundation_modelheterogeneous_graph_transformer+5

    Heterograph foundation model for metabolic engineering, fusing protein, chemistry, and text embeddings over a 6.9M-node biological knowledge graph.

    ProteinSmall moleculeDNA & Gene
    21Openness
  • ProLoc

    Nanjing UniversityJune 27, 2026functional_region_localizationlanguage_modelmultimodal+3

    Text-guided localization model that grounds natural-language functional descriptions to specific residue regions of a protein sequence.

    ProteinLanguage model
    10Openness
  • eRNAformer

    2
    Nanchang UniversityJune 27, 2026cnnenhancer_annotationgenomics+5

    Enhancer RNA mapping model that locates eRNA loci genome-wide from DNA sequence and aggregated RNA-seq signal using a CNN-transformer architecture.

    DNA & GeneRNA
    95Openness
  • PertOmni

    1
    Yale University +2 othersJune 26, 2026cell_biologycontrastive_learningdrug_gene_interaction+6

    Contrastive multimodal model for perturbation screens, aligning transcriptomic signatures with text and cell-painting image embeddings.

    Single-cellSmall molecule
    18Openness
  • Molexar

    717
    Peking UniversityJune 24, 2026de_novo_designdrug_designdrug_discovery+5

    Multimodal molecular generation model for drug design, conditioned on properties, pharmacophores, protein sequences, or protein binding pockets.

    Small moleculeProtein
    82Openness
  • Helmholtz MunichJune 22, 2026cell_biologycontrastive_learningfluorescence_microscopy+6

    Self-supervised 3D masked autoencoder for volumetric fluorescence microscopy, aligned to ESM2 embeddings to predict protein localization.

    ImagingSingle-cell
    71Openness
  • BioMatrix

    41167
    Shanghai AI Laboratory +1 otherJune 20, 2026foundation_modellanguage_modelmolecule_generation+6

    Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.

    ProteinSmall moleculeLanguage model
    67Openness
  • vBx-1.0

    Verge LabsJune 16, 2026contrastive_learningfoundation_modelgene_expression+5

    Multimodal foundation model for precision neurology that reconstructs a patient's molecular brain state from blood to predict disease progression.

    Single-cellDNA & Gene
    5Openness
  • RepGene

    BGI ResearchJune 15, 2026autoencodergenomicsmultimodal+5

    Gene representation framework fusing DNA, transcript, protein, text, and single-cell embeddings into one latent space that survives missing views.

    DNA & GeneProteinSingle-cell
    22Openness
  • Omnii

    Radical NumericsJune 15, 2026convolutionaldnafoundation_model+6

    Genomic language model from Radical Numerics with a 2 Mbp context window, built for zero-shot variant effect prediction and sequence design.

    DNA & Gene
    5Openness
  • RDiffusion

    Zhejiang University +6 othersJune 13, 2026de_novo_designdiffusionfoundation_model+5

    Diffusion-based generative RNA model for de novo sequence design, conditioned on function, RNA family, structure, or binding proteins.

    RNA
    5Openness
  • SpineAgent

    6
    University of WashingtonJune 7, 2026contrastive_learningfoundation_modelimage_classification+8

    Multi-sequence spine MRI foundation model with DINOv3 encoders, supporting condition classification, pathology localization, and report generation.

    Imaging
    55Openness
  • Chai-3

    Chai DiscoveryJune 4, 2026antibodyantibody_designdrug_discovery+4

    Generative foundation model for antibody and multispecific design, doubling its predecessor's experimental success rate on therapeutic targets.

    Protein
    4Openness
  • SQUALL

    Peking UniversityJune 3, 2026biomarker_discoveryfoundation_modelgene_expression+6

    Multimodal foundation model pretrained on 1.76B histology and spatial transcriptomics spots, inferring molecular state from whole-slide images.

    PathologySpatial omics
    6Openness
  • TARIO-2

    NoetikJune 1, 2026foundation_modelgene_expressionhistology+4

    Tumor foundation model that infers whole-transcriptome and microenvironment signal from H&E slides, pretrained on paired spatial transcriptomics.

    PathologySpatial omics
    6Openness
  • Vermeer

    3
    Microsoft Research +2 othersJune 1, 2026autoregressivecell_biologyfluorescence_microscopy+7

    Generative microscopy foundation model that synthesizes in-silico fluorescence images of protein subcellular localization from amino-acid sequence.

    ImagingProtein
    17Openness
  • AMix-2

    Shanghai AI Laboratory +4 othersMay 30, 2026diffusionfold_classificationfoundation_model+6

    Protein-text foundation model placing amino acid sequences and natural language in one token space for protein understanding and de novo design.

    ProteinLanguage model
    10Openness
  • Nanjing University +2 othersMay 30, 2026foundation_modelgene_expression_predictionhistology+5

    Tri-modal foundation model unifying histology images, spatial transcriptomics, and language for zero-shot pathology and spatial biology reasoning.

    PathologySpatial omics
    65Openness
  • STMDiT

    ETH Zurich +1 otherMay 29, 2026diffusion_transformergenerativehistology+4

    Diffusion transformer for virtual tissue synthesis, generating H&E histopathology patches conditioned on spatial gene expression and morphology.

    PathologySpatial omics
    44Openness
  • University of FloridaMay 18, 2026bertbilstmcnn+11

    Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.

    DNA & Gene
    45Openness
  • Bio-BLIP

    Stanford UniversityMay 15, 2026foundation_modelgenomicsmendelian_disease+7

    Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.

    DNA & GeneLanguage model
    23Openness
  • ProtLiD

    6
    National University of SingaporeMay 15, 2026de_novo_designdiffusiongenerative+6

    370M-parameter ligand-conditioned discrete diffusion model that co-designs protein sequence and structure under explicit small-molecule constraints.

    Protein
    5Openness
  • SpaRank

    Guangxi UniversityMay 13, 2026foundation_modelmultimodalspatial_transcriptomics+2

    Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.

    Spatial omics
    8Openness