All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 73–96 of 125 filtered models
Evolla
69239Multimodal 80B-parameter protein-language model that answers natural language questions about protein function from sequence and structure.
Protein67OpennessppLM-CO
———Codon optimization framework that adds a generative head to a frozen ProtBert protein language model to design highly expressed coding sequences.
RNAProtein12OpennessBiMediX2
742120Mohamed bin Zayed University of Artificial IntelligenceDecember 10, 2024histologyinstruction_tuninglanguage_model+7Bilingual Arabic-English medical multimodal model built on Llama 3.1 for radiology, CT, and histology image understanding and question answering.
Language modelImagingPathology11OpennessAIDO.Protein
1682290Mixture-of-experts protein language model scaling to 16 billion parameters, applied to variant effect prediction and de novo protein design.
Protein29OpennessLOL-EVE
238Conditional autoregressive genomic language model trained on 13.6M mammalian promoters, scoring promoter variants, including indels, zero-shot.
DNA & Gene89Opennessp-IgGen
13297Oxford Protein Informatics Group (OPIG) +1 otherNovember 9, 2024antibodyde_novo_designfoundation_model+5Antibody language model that generates paired heavy and light variable domains, with a developability-conditioned variant for manufacturable designs.
Protein68OpennessSleepGPT
22——Language model over whole-night sleep stage sequences that corrects automated sleep staging and supplies features for sleep disorder diagnosis.
Biosignals51OpennessMedRegA
462913Hong Kong University of Science and Technology +1 otherOctober 24, 2024histologyimage_classificationinstruction_tuning+8Region-aware bilingual medical multimodal LLM that handles image- and region-level vision-language tasks across eight imaging modalities.
PathologyLanguage model65OpennessPSALM
———Protein domain annotation model pairing an ESM-2 backbone with a probabilistic decoder, bringing language-model sensitivity to Pfam-style assignment.
Protein91OpennessSeqDance / ESMDance
61880Protein language models trained on biophysical dynamics from MD simulations and normal-mode analysis; ESMDance builds on ESM2 for variant effects.
Protein84OpennessChromatin-state language model pretrained on ROADMAP annotations from 127 human cell types to find chromatin-state motifs and predict gene expression.
DNA & Gene86OpennessCell2Sentence
87486865Framework turning single-cell expression profiles into ranked gene-name sequences, letting off-the-shelf language models generate and annotate cells.
Single-cell74OpennessCompute-Optimal PLM
1138—Scaling-law study of protein language models identifying compute-optimal training for causal and masked objectives on 939 million protein sequences.
Protein22OpennessLOBSTER
1657—Efficient protein language model library from Prescient Design enabling high-quality sequence representations and fitness prediction in 24 GPU hours.
Protein69OpennessOpenCRISPR-1
1.2K80—AI-designed CRISPR-Cas9 gene editor generated by protein language models trained on 1.2 million CRISPR operons and shown to edit the human genome.
Protein16OpennessM3D
454172924Multimodal large language model for 3D medical imaging that handles report generation, visual question answering, and segmentation on CT volumes.
ImagingLanguage model77OpennessPLMSearch
8086—Protein language model-based sequence search that detects remote homologs with threefold higher sensitivity than MMseqs2 at comparable speed.
Protein90OpennessERNIE-RNA
44431.8KRNA language model that builds base-pairing constraints into self-attention, pretrained on 20.4 million sequences for structure and function tasks.
RNA46OpennessCaduceus
2482232.6KBidirectional, reverse-complement equivariant DNA language models built on Mamba state space models for long-range variant effect prediction.
DNA & Gene86Openness