All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 518 filtered models

  • TCRDiff

    7
    Monash UniversityJune 14, 2026antibodyde_novo_designdiffusion+5

    Conditional denoising diffusion model that designs antigen-specific TCR CDR3β sequences conditioned on peptide-MHC targets and germline V-genes.

    Protein
    75Openness
  • BetaInfer

    Technion – Israel Institute of Technology +2 othersJune 14, 2026generativegenomicsmolecular_evolution+4

    Generative transformer for phylogenetic inference that transduces sets of unaligned molecular sequences directly into Newick-format trees.

    DNA & GeneProtein
    8Openness
  • MoE-Bind

    2
    University of North BengalJune 13, 2026autoregressivede_novo_designgenerative+6

    Protein binder generator producing receptor-conditioned binders from sequence alone, using a sparse Mixture-of-Experts transformer with no 3D input.

    Protein
    54Openness
  • RNARL

    Shanghai Jiao Tong University +2 othersJune 13, 2026codoncodon_optimizationgenerative+6

    Reinforcement-learning generative framework for multi-objective RNA codon optimization that generalizes across six species and five RNA types.

    RNA
    4Openness
  • DNAGPT2

    CEITEC Masaryk UniversityJune 12, 2026dnadna_language_modelinggenomics+5

    Family of ten compact GPT-2 decoder-only DNA language models spanning BPE vocabularies from 16 to 8192 tokens, built for lossless genome compression.

    DNA & Gene
    52Openness
  • GermRL

    14
    Johns Hopkins UniversityJune 11, 2026antibodyantibody_designde_novo_design+6

    Reinforcement learning framework that fine-tunes the ProGen2-OAS antibody language model with GRPO to cut germline bias in generated sequences.

    Protein
    65Openness
  • HoloCell

    Beijing Zhongguancun AcademyJune 11, 2026cross_modal_generationdiffusionepigenomics+7

    860M-parameter generative single-cell foundation model that jointly represents and generates epigenomic, transcriptomic, and proteomic modalities.

    Single-cellDNA & Gene
    21Openness
  • TifBERT

    2
    York UniversityJune 11, 2026bertfoundation_modelgene_expression+5

    Bulk RNA-seq foundation model learning normalization-robust transcriptome representations via TF-IDF gene ordering and masked gene modeling.

    RNA
    17Openness
  • Promera

    83
    MIT +1 otherJune 10, 2026antibodybinder_designdiffusion+5

    Unified all-atom generative model for biomolecular structure prediction, binder filtering, and controllable protein and nanobody design.

    Protein
    61Openness
  • BacteReason

    University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5

    Reasoning LLM that predicts antimicrobial susceptibility of clinical bacterial isolates and supplies mechanistic explanations for each prediction.

    DNA & GeneLanguage model
    20Openness
  • CREP

    University of OxfordJune 7, 2026cis_regulatory_element_annotationdnaregulatory_genomics+4

    Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.

    DNA & Gene
    8Openness
  • MethylSeqNet

    University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6

    Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.

    DNA & Gene
    18Openness
  • SpineAgent

    6
    University of WashingtonJune 7, 2026contrastive_learningfoundation_modelimage_classification+8

    Multi-sequence spine MRI foundation model with DINOv3 encoders, supporting condition classification, pathology localization, and report generation.

    Imaging
    55Openness
  • tf-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+5

    Transcription factor-DNA binding specificity prediction from sequence, with a physics-derived dual-encoder trained by symmetric contrastive learning.

    DNA & Gene
    18Openness
  • drug-SFM

    1
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldrug_repurposing+8

    Specificity foundation model predicting small-molecule drug-target binding from sequence, scored as cross-modal retrieval without docking or assays.

    Small molecule
    16Openness
  • ReCLIP

    University of Chicago +2 othersJune 4, 2026multi_taskprotein_protein_interaction_predictionproteomics+4

    Transformer that predicts protein-protein interactions at residue resolution, spanning mutations, PTMs, peptide-MHC binding, and disease variants.

    Protein
    22Openness
  • crisprSFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcrisprcross_modal_retrieval+6

    CRISPR off-target prediction model that scores gRNA-DNA specificity from sequence, framing guide-target recognition as cross-modal retrieval.

    DNA & Gene
    19Openness
  • Emap2lig

    2
    Kihara Lab +1 otherJune 4, 2026atomic_modelingcryo_emdiffusion+6

    Cryo-EM ligand modeling pipeline that detects bound ligand densities in a map, then reconstructs their atomic structures with a diffusion model.

    ImagingSmall molecule
    25Openness
  • enzyme-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Enzyme-substrate specificity model that scores catalytic pairs from sequence with a physics-derived dual-encoder and a contrastive objective.

    Protein
    23Openness
  • FlashABB

    19
    Oxford Protein Informatics Group (OPIG)June 4, 2026antibodydevelopability_predictionfoundation_model+4

    Pretrained antibody structure predictor that outputs full paired heavy/light 3D structures faster than protein language models generate embeddings.

    Protein
    54Openness
  • mhcSFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Peptide-MHC binding specificity model that frames presentation as cross-modal retrieval, aligning peptide and MHC encoders by contrastive learning.

    Protein
    23Openness
  • mir-SFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldual_encoder+6

    Foundation model that predicts microRNA-mRNA target specificity from sequence, using a dual-encoder trained with a symmetric contrastive objective.

    RNA
    25Openness
  • LDARNet

    41
    Independent ResearcherJune 3, 2026dnafoundation_modelgene_expression+6

    Genomic foundation model with 120M parameters that learns adaptive DNA token boundaries by dynamic chunking, not fixed k-mer or byte-pair tokens.

    DNA & Gene
    26Openness
  • SQUALL

    Peking UniversityJune 3, 2026biomarker_discoveryfoundation_modelgene_expression+6

    Multimodal foundation model pretrained on 1.76B histology and spatial transcriptomics spots, inferring molecular state from whole-slide images.

    PathologySpatial omics
    6Openness