All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–37 of 37 filtered models
FOCUS
———Generative foundation model that imputes genes and denoises spatial transcriptomics, conditioned on H&E histology, scRNA-seq, and spatial priors.
Spatial omicsPathologySingle-cell4OpennessscMOBA
———Chinese Academy of Sciences +1 otherDecember 2, 2025cell_biologycell_type_annotationdata_integration+5Conversational single-cell and spatial multi-omics brain foundation model, with zero-shot cell annotation and disease prediction across species.
Single-cellLanguage model5OpennessSpatial transcriptomics language model that reads tissue as spatial sentences to simulate cell profiles and run in silico perturbations.
Spatial omicsSingle-cell53OpennessMIMYR
—2—Generative framework that reconstructs missing spatial transcriptomics regions by jointly predicting cell locations, cell types, and gene expression.
Spatial omicsSingle-cell16OpennessSIGMMA
—1—Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.
PathologySpatial omics20OpennessSHEST
1——Samsung Advanced Institute for Health Sciences and Technology +2 othersNovember 19, 2025cell_type_annotationgene_expressionhistology+5Histopathology model that predicts single-cell type composition and reconstructs spatial gene expression from H&E slides, with no molecular assay.
PathologySpatial omics16OpennessKidney-specialized single-cell foundation model trained across four mammalian species for zero-shot cell-type annotation and batch integration.
Single-cellSpatial omics22OpennessDeepSpot2Cell
152—Predicts virtual single-cell spatial transcriptomics from H&E histology using frozen pathology foundation models and spot-level supervision.
PathologySpatial omics58OpennessHistology vision transformer with 80M parameters that predicts spatial gene expression from H&E tissue images and transfers to tumor detection.
PathologySpatial omics59OpennessTera-MIND
12—Patch-based 3D diffusion model that generates teravoxel-scale virtual mouse brain volumes conditioned on spatially resolved gene expression.
Spatial omicsImaging78OpennessSpatialEx
38——Jilin University +1 otherFebruary 23, 2025contrastive_learningfoundation_modelgene_expression_prediction+6Histology-anchored framework pairing an H&E foundation model with a cellular hypergraph to predict single-cell multi-omics from tissue images.
Spatial omicsPathology57OpennessNicheformer
167144945Transformer foundation model pretrained on 110M single-cell and spatial transcriptomics profiles, transferring spatial context to dissociated cells.
Single-cell87Openness