All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 209 filtered models
OmniGene-4
—1—Unified bio-language Mixture-of-Experts model spanning DNA, protein sequence and structure, and biological text across eight task families.
Language modelDNA & GeneProtein7OpennessBRIDGE
———The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.
PathologySpatial omics31OpennessA-CODE
———All-atom protein co-design model that generates sequence and structure together in one unified diffusion process, aimed at hard binder design.
Protein8Openness- University of KentuckyMay 4, 2026contrastive_learningintrinsic_disorder_predictionmolecular_dynamics+6
Protein language model aligning ESM sequence embeddings with molecular dynamics trajectories for zero-shot mutation effect and stability prediction.
Protein10Openness DoFormer
———Causal multimodal transformer that embeds the do-operator in attention to predict single-cell gene expression under unseen genetic perturbations.
Single-cell8OpennessProteo-R1
6453.2KReasoning-guided foundation model for de novo antibody CDR design, pairing a multimodal LLM understanding expert with a Boltz-1 diffusion expert.
Protein53OpennessscPert
———Multi-modal transformer fusing LLM gene embeddings with biological knowledge graphs to predict single-cell responses to genetic perturbations.
Single-cell14OpennessMIMIC
37——Generative multimodal foundation model spanning DNA, RNA, and protein, with any-to-any inference across genome, transcriptome, and proteome.
RNAProteinDNA & Gene16OpennessGenNA
———Autoregressive nucleotide-and-text foundation model generating DNA and RNA sequences from natural-language prompts that name species and function.
DNA & GeneRNA16OpennessH2O
———Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6Pathology foundation model that infers spatial transcriptomics and proteomics directly from routine H&E whole-slide images, with no spatial assay.
PathologySpatial omics7Openness110M-parameter RNA language model that designs sequences from secondary structure, motif, and Gene Ontology constraints via discrete diffusion.
RNA48OpennessRVQ-Alpha
———Single-cell foundation model that tokenizes scRNA-seq into 10 tokens in a Qwen3-4B vocabulary for cell type annotation and perturbation prediction.
Single-cell4OpennessProtein function prediction model that fuses sequence, structure, text, and interaction embeddings with learned gating to assign Gene Ontology terms.
Protein84OpennessHalo
———Whole-cell segmentation model for spatial transcriptomics that fuses DAPI nuclear images with RNA transcript density to recover true cell boundaries.
Spatial omics63OpennessMuPD
———Diffusion-transformer pathology model embedding H&E histology, RNA profiles, and clinical text in a latent space for zero-shot cross-modal synthesis.
PathologySpatial omics15OpennessSTORM
—3—Stanford UniversityApril 4, 2026clinical_outcome_predictionfoundation_modelgene_expression_prediction+6Spatial transcriptomics foundation model pairing gene expression with H&E histology for spatial domain discovery and clinical outcome prediction.
Spatial omicsPathology17OpennessCLOP-DiT
———Generates single-cell transcriptomes from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.
Single-cell10OpennessBioReason-Pro
1229—Multimodal reasoning LLM for protein function prediction, fusing protein language model embeddings to emit interpretable GO-term reasoning traces.
ProteinLanguage model58OpennessSELFormerMM
3——Multimodal molecular foundation model fusing SELFIES, 2D graphs, text, and knowledge graphs via contrastive pretraining for property prediction.
Small molecule55OpennessPro2RNA
———Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.
RNAProtein10OpennessSpatialFusion
40——Multimodal foundation model integrating spatial transcriptomics, H&E histopathology, and pathway scores for single-cell niche discovery.
Spatial omicsSingle-cellPathology71OpennessEEG-to-text foundation model that turns raw recordings into clinically grounded natural-language narratives instead of fixed-label classifications.
Biosignals18OpennessProtAlign
———Lawrence Livermore National LaboratoryMarch 6, 2026contrastive_learningcross_modal_retrievalembeddings+4Cross-modal protein encoder that aligns ESM-2 sequence embeddings with ProteinMPNN structure embeddings in a shared space for cross-modal retrieval.
Protein35Openness