All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 552 filtered models

  • RDiffusion

    Zhejiang University +6 othersJune 13, 2026de_novo_designdiffusionfoundation_model+5

    Diffusion-based generative RNA model for de novo sequence design, conditioned on function, RNA family, structure, or binding proteins.

    RNA
    5Openness
  • HoloCell

    Beijing Zhongguancun AcademyJune 11, 2026cross_modal_generationdiffusionepigenomics+7

    860M-parameter generative single-cell foundation model that jointly represents and generates epigenomic, transcriptomic, and proteomic modalities.

    Single-cellDNA & Gene
    21Openness
  • TifBERT

    2
    York UniversityJune 11, 2026bertfoundation_modelgene_expression+5

    Bulk RNA-seq foundation model learning normalization-robust transcriptome representations via TF-IDF gene ordering and masked gene modeling.

    RNA
    17Openness
  • MethylSeqNet

    University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6

    Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.

    DNA & Gene
    18Openness
  • SpineAgent

    6
    University of WashingtonJune 7, 2026contrastive_learningfoundation_modelimage_classification+8

    Multi-sequence spine MRI foundation model with DINOv3 encoders, supporting condition classification, pathology localization, and report generation.

    Imaging
    55Openness
  • DaX

    2
    DAMO AcademyJune 5, 2026biomarker_predictioncancer_subtypingdino+5

    Pathology vision foundation model adapting DINOv3 self-supervised learning to whole-slide histopathology across many magnifications and scales.

    Pathology
    11Openness
  • tf-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+5

    Transcription factor-DNA binding specificity prediction from sequence, with a physics-derived dual-encoder trained by symmetric contrastive learning.

    DNA & Gene
    18Openness
  • drug-SFM

    1
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldrug_repurposing+8

    Specificity foundation model predicting small-molecule drug-target binding from sequence, scored as cross-modal retrieval without docking or assays.

    Small molecule
    16Openness
  • Chai-3

    Chai DiscoveryJune 4, 2026antibodyantibody_designdrug_discovery+4

    Generative foundation model for antibody and multispecific design, doubling its predecessor's experimental success rate on therapeutic targets.

    Protein
    4Openness
  • crisprSFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcrisprcross_modal_retrieval+6

    CRISPR off-target prediction model that scores gRNA-DNA specificity from sequence, framing guide-target recognition as cross-modal retrieval.

    DNA & Gene
    19Openness
  • enzyme-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Enzyme-substrate specificity model that scores catalytic pairs from sequence with a physics-derived dual-encoder and a contrastive objective.

    Protein
    23Openness
  • FlashABB

    19
    Oxford Protein Informatics Group (OPIG)June 4, 2026antibodydevelopability_predictionfoundation_model+4

    Pretrained antibody structure predictor that outputs full paired heavy/light 3D structures faster than protein language models generate embeddings.

    Protein
    54Openness
  • mhcSFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Peptide-MHC binding specificity model that frames presentation as cross-modal retrieval, aligning peptide and MHC encoders by contrastive learning.

    Protein
    23Openness
  • mir-SFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldual_encoder+6

    Foundation model that predicts microRNA-mRNA target specificity from sequence, using a dual-encoder trained with a symmetric contrastive objective.

    RNA
    25Openness
  • LDARNet

    41
    Independent ResearcherJune 3, 2026dnafoundation_modelgene_expression+6

    Genomic foundation model with 120M parameters that learns adaptive DNA token boundaries by dynamic chunking, not fixed k-mer or byte-pair tokens.

    DNA & Gene
    26Openness
  • SQUALL

    Peking UniversityJune 3, 2026biomarker_discoveryfoundation_modelgene_expression+6

    Multimodal foundation model pretrained on 1.76B histology and spatial transcriptomics spots, inferring molecular state from whole-slide images.

    PathologySpatial omics
    6Openness
  • BrainGFM

    173
    Lehigh University +1 otherJune 2, 2026brain_connectomedisorder_classificationfmri+7

    Graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero-shot disorder classification.

    Biosignals
    16Openness
  • TARIO-2

    NoetikJune 1, 2026foundation_modelgene_expressionhistology+4

    Tumor foundation model that infers whole-transcriptome and microenvironment signal from H&E slides, pretrained on paired spatial transcriptomics.

    PathologySpatial omics
    6Openness
  • CryoProt

    Hunan University +1 otherJune 1, 2026active_site_identificationbinding_affinitycryo_em+7

    Protein representation learning from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.

    ImagingProtein
    11Openness
  • TESSERA

    5
    Weill Cornell MedicineJune 1, 2026cancer_genomicscell_type_annotationcontrastive_learning+5

    Self-supervised foundation model that embeds cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types for tumor subtyping.

    DNA & Gene
    28Openness
  • Vermeer

    3
    Microsoft Research +2 othersJune 1, 2026autoregressivecell_biologyfluorescence_microscopy+7

    Generative microscopy foundation model that synthesizes in-silico fluorescence images of protein subcellular localization from amino-acid sequence.

    ImagingProtein
    17Openness
  • mRNAutilus

    1
    Atom Bioworks +3 othersMay 31, 2026de_novo_designdiffusionfoundation_model+5

    Masked discrete-diffusion model over millions of full-length mRNAs, steered by Monte Carlo tree search for joint codon optimization and UTR design.

    RNA
    7Openness
  • TxFM

    2
    Recursion PharmaceuticalsMay 31, 2026autoencoderfoundation_modelgene_expression+4

    Transcriptomics foundation model from Recursion that masks and reconstructs RNA-seq gene expression counts to learn reusable sample embeddings.

    Single-cell
    12Openness
  • AMix-2

    Shanghai AI Laboratory +4 othersMay 30, 2026diffusionfold_classificationfoundation_model+6

    Protein-text foundation model placing amino acid sequences and natural language in one token space for protein understanding and de novo design.

    ProteinLanguage model
    10Openness