All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 55 filtered models

  • OpticalDNA

    Hunan UniversityFebruary 2, 2026dnafoundation_modelgenomics+5

    Vision-language DNA model that renders genomic sequence as visual layouts, reading regions up to 450,000 bases with about 20x better token efficiency.

    DNA & Gene
    16Openness
  • Beijing Zhongguancun Academy +4 othersJanuary 29, 2026autoregressivednafoundation_model+6

    Family of autoregressive genomic foundation models that reconcile k-mer tokenization with single-nucleotide resolution at contexts up to 98k bp.

    DNA & Gene
    86Openness
  • Gengram

    51
    Zhejiang LabJanuary 29, 2026dnafoundation_modelgenomics+5

    Retrieval-augmented genomic foundation model that gives transformer backbones a hash-based k-mer motif memory for functional genomics tasks.

    DNA & Gene
    83Openness
  • DNAChunker

    1
    KAIST +1 otherJanuary 6, 2026dnafunctional_genomicsgenomics+4

    Masked DNA language model with a learnable, adaptive tokenizer that produces context-dependent, variable-length segments instead of fixed k-mers.

    DNA & Gene
    23Openness
  • MetagenBERT

    MetagenBERT AuthorsJanuary 5, 2026bertdnaembeddings+5

    Annotation-free metagenome embedding pipeline that encodes raw DNA reads with genomic language models and pools them via FAISS k-means clustering.

    DNA & Gene
    22Openness
  • InstaDeep +4 othersDecember 22, 2025de_novo_designdnafoundation_model+5

    Multi-species genomics foundation model spanning representation learning, functional-track prediction, and sequence generation at 1 Mb context.

    DNA & Gene
    25Openness
  • Huazhong University of Science and TechnologyDecember 8, 2025dnafoundation_modelgene_expression+6

    Plant genome foundation model pairing a bidirectional Mamba backbone with sparse Mixture-of-Experts, pretrained on 25.4B nucleotides from 42 species.

    DNA & Gene
    53Openness
  • Brown UniversityNovember 25, 2025dnafoundation_modelgenomics+5

    Bidirectional state-space (Mamba-2) genomic model for ultra-long extrachromosomal circular DNA, scaling linearly with sequence length.

    DNA & Gene
    54Openness
  • Puget

    University of WashingtonNovember 20, 2025chromatindnafoundation_model+6

    Gene expression prediction model combining DNA sequence with Hi-C contact maps to capture 3D chromatin looping behind cell-type-specific expression.

    DNA & Gene
    8Openness
  • MethylAI

    7
    Guangzhou National LaboratoryNovember 20, 2025cnndnaepigenetics+6

    Cross-species-pretrained CNN that predicts single-CpG DNA methylation from genomic sequence and interprets the cis-regulatory motifs that govern it.

    DNA & Gene
    64Openness
  • Chan Zuckerberg Initiative +1 otherNovember 2, 2025dnafoundation_modelgene_expression+4

    Hierarchical transformer with 1.2 billion parameters that predicts personalized gene expression from diploid genomes for variant effect prediction.

    DNA & Gene
    68Openness
  • NyxBind

    12
    Hong Kong University of Science and TechnologyOctober 21, 2025bertbinding_site_predictioncontrastive_learning+5

    Transcription factor binding site prediction model that refines a DNABERT-2 backbone with contrastive learning across diverse TFBS types.

    DNA & Gene
    40Openness
  • EiRA

    2
    Hunan UniversitySeptember 2, 2025binder_designdnagenerative+6

    Protein binder design model post-trained from a multimodal protein language model to bind proteins, peptides, small molecules, and nucleic acids.

    Protein
    13Openness
  • BioFM

    6
    M42March 27, 2025dnafoundation_modelgene_expression+5

    265M-parameter genomic foundation model whose BioToken scheme folds variants and region annotations into the tokens for variant effect prediction.

    DNA & Gene
    4Openness
  • Evo 2

    4K28811.8K
    Arc InstituteFebruary 21, 2025dnafoundation_modelgenerative+2

    Genomic foundation model trained on 9.3 trillion DNA base pairs across all domains of life, with 40B parameters and a 1-million-token context.

    DNA & Gene
    92Openness
  • AIDO.DNA

    1681783
    genbio.aiDecember 1, 2024bertdnafoundation_model+7

    DNA foundation model scaling an encoder-only transformer to 7 billion parameters for variant effect prediction, gene expression, and sequence design.

    DNA & Gene
    27Openness
  • Evo

    1.5K2501.8K
    Arc InstituteNovember 15, 2024dnafoundation_modelgenomics+2

    Genomic foundation model with 7B parameters that models prokaryotic DNA, RNA, and protein at single-nucleotide resolution over a 131k-token context.

    DNA & Gene
    70Openness
  • OpenCRISPR-1

    1.2K80
    ProfluentApril 22, 2024de_novo_designdnafoundation_model+5

    AI-designed CRISPR-Cas9 gene editor generated by protein language models trained on 1.2 million CRISPR operons and shown to edit the human genome.

    Protein
    16Openness
  • DNABERT-S

    1305324.1K
    MAGICS LabFebruary 13, 2024contrastive_learningdnaembeddings+3

    DNA embedding model built on DNABERT-2, using contrastive learning to cluster sequences by species for metagenomic binning without labeled data.

    DNA & Gene
    53Openness
  • CaLM

    5445
    Oxford Protein Informatics Group (OPIG)January 1, 2024bertcodondna+3

    Codon-level BERT model that captures genomic signals invisible to amino acid models, outperforming billion-parameter PLMs with just 86M parameters.

    Protein
    66Openness
  • GPN

    34931.7K
    Song LabOctober 31, 2023dnafoundation_modelgenomics+2

    DNA language model for genome-wide variant effect prediction, trained by masked language modeling on multispecies genomes with no labeled data.

    DNA & Gene
    93Openness
  • GPN-MSA

    34990216
    UC BerkeleyOctober 11, 2023dnafoundation_modelgenomics+2

    DNA language model for variant effect prediction across coding and non-coding regions, using whole-genome alignments of 100 vertebrate species.

    DNA & Gene
    87Openness
  • DNAGPT

    46
    TencentAILabHealthcareJuly 11, 2023dnafoundation_modelgenerative+1

    GPT-style DNA foundation model trained on over 200 billion base pairs of mammalian genomes for sequence generation, classification, and regression.

    DNA & Gene
    6Openness
  • DNABERT-2

    507456170.4K
    MAGICS LabJune 26, 2023cross_speciesdnafoundation_model+2

    Multi-species genomic foundation model swapping k-mer tokenization for byte pair encoding, matching Nucleotide Transformer with 21x fewer parameters.

    DNA & Gene
    64Openness