All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 49 filtered models

  • CREP

    University of OxfordJune 7, 2026cis_regulatory_element_annotationdnaregulatory_genomics+4

    Fine-tuned Enformer derivative that predicts discrete, interpretable cis-regulatory element class annotations (enhancer, promoter, insulator) directly from DNA sequence across human cell types.

    DNA & Gene
    8Openness
  • tf-SFM

    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Specificity Foundation Model that predicts transcription factor-DNA binding specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.

    DNA & Gene
    18Openness
  • crisprSFM

    ETH ZurichJune 4, 2026contrastive_learningcrisprcross_modal_retrieval+6

    Specificity Foundation Model that predicts CRISPR gRNA off-target DNA specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.

    DNA & Gene
    19Openness
  • LDARNet

    1
    Independent ResearcherJune 3, 2026dnafoundation_modelgene_expression+6

    A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.

    DNA & Gene
    26Openness
  • DanioDecima

    Chan Zuckerberg BiohubMay 29, 2026cnnde_novo_designdna+7

    A zebrafish DNA sequence-to-function model predicting cell-type-specific single-cell expression across 85 cell-type x developmental-timepoint combinations during embryogenesis.

    DNA & GeneSingle-cell
    22Openness
  • OryzaG3

    Hainan UniversityMay 26, 2026causal_language_modeldnagenomic_variant_prediction+8

    A 700M-parameter DNA language model pretrained on the rice pangenome, built as a reusable foundation model for crop genomics and molecular breeding.

    DNA & Gene
    19Openness
  • PlasmidLM

    University College LondonMay 19, 2026dnalanguage_modelplasmid_design+4

    A promptable DNA language model that generates multi-kilobase plasmid sequences from human-readable component specifications, post-trained with verifiable rewards.

    DNA & Gene
    49Openness
  • University of FloridaMay 18, 2026bertbilstmcnn+11

    Multimodal deep-learning framework that detects and localizes DNA lesions directly from native nanopore sequencing, built on the damage-aware LesionBERT foundation model.

    DNA & Gene
    45Openness
  • OmniGene-4

    Huazhong University of Science and TechnologyMay 12, 2026dnafoundation_modelinstruction_following+7

    A unified bio-language Mixture-of-Experts foundation model spanning DNA, protein sequence and structure, and biological text, applied across eight task families from a single checkpoint.

    Language modelDNA & GeneProtein
    7Openness
  • Wisteria

    Inner Mongolia UniversityMay 7, 2026cnndnafoundation_model+6

    A pretrained DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier-based attention to capture multi-scale genomic regulatory patterns.

    DNA & Gene
    10Openness
  • Carbon

    1937.4K
    Hugging Face +2 othersMay 1, 2026dnafoundation_modelgenerative+3

    An open autoregressive genomic foundation model (0.5B–8B params) with a 6-mer DNA tokenizer, matching Evo2-7B win rates at far higher throughput.

    DNA & Gene
    93Openness
  • Zhejiang Lab +1 otherApril 21, 2026chromatinchromatin_accessibilitydna+8

    A 1.25B-parameter Mixture-of-Experts genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window.

    DNA & Gene
    90Openness
  • GPT-Rosalind

    2.8K
    OpenAIApril 16, 2026dnadrug_discoveryfoundation_model+9

    OpenAI's first life-sciences frontier reasoning model, optimized for multi-step scientific workflows spanning protein engineering, genomics, drug-target discovery, and biochemistry reasoning.

    Language model
    5Openness
  • OmniNA

    25
    Beijing Institute of Genomics +1 otherApril 13, 2026dnafoundation_modelgenome+7

    Self-supervised generative foundation model jointly trained on 91.7M nucleotide sequences and structured annotations spanning 1.076 trillion bases, achieving SOTA on 23 nucleotide-language benchmarks.

    DNA & Gene
    42Openness
  • PatchDNA

    2
    Relation TherapeuticsMarch 12, 2026dnafoundation_modelgenomics+4

    A DNA language model that replaces fixed tokenization with conservation-guided patching, letting models up to 10x smaller match or beat state-of-the-art genomic benchmarks.

    DNA & Gene
    33Openness
  • Institute of Hydrobiology, Chinese Academy of SciencesMarch 9, 2026dnafoundation_modelgenome_annotation+4

    Genomic foundation model for Cypriniformes fish, built on a Mamba-2 state space model with a 32 kb context window for long-range genome modeling.

    DNA & Gene
    50Openness
  • D3LM

    1
    Renmin University of ChinaMarch 2, 2026diffusiondnafoundation_model+6

    A bidirectional masked discrete diffusion language model over DNA, initialized from Nucleotide Transformer v2, that unifies DNA understanding and generation.

    DNA & Gene
    58Openness
  • BOTANIC-0

    1
    Living ModelsFebruary 23, 2026dnafoundation_modelgene_expression+5

    Family of plant genomic foundation models (0.1B-1B params) pretrained on 43 phylogenetically diverse plant genomes for regulatory, expression, and variant tasks.

    DNA & Gene
    19Openness
  • NVIDIAFebruary 19, 2026dnafoundation_modelgenomics+5

    A training framework that grounds genomic foundation models with a joint-embedding predictive objective, learning to predict functional representations of masked DNA rather than reconstructing tokens.

    DNA & Gene
    54Openness
  • dnaHNet

    1
    Arc Institute +2 othersFebruary 11, 2026dnafoundation_modelgene_essentiality_prediction+7

    A tokenizer-free, hierarchical autoregressive genomic foundation model that adaptively chunks raw nucleotides, enabling efficient long-context learning and zero-shot variant and gene predictions.

    DNA & Gene
    12Openness
  • AntigenLM

    Chinese Academy of Sciences +1 otherFebruary 9, 2026dnafoundation_modelgenerative+5

    A structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.

    DNA & Gene
    5Openness
  • OpticalDNA

    Hunan UniversityFebruary 2, 2026dnafoundation_modelgenomics+5

    An OCR-inspired vision-language model that renders DNA as visual layouts to analyze long genomic sequences with far fewer tokens than sequential tokenizers.

    DNA & Gene
    16Openness
  • Beijing Zhongguancun Academy +4 othersJanuary 29, 2026autoregressivednafoundation_model+6

    A family of autoregressive genomic foundation models that reconcile k-mer tokenization with single-nucleotide resolution at contexts up to 98k bp.

    DNA & Gene
    86Openness
  • Gengram

    48
    Zhejiang LabJanuary 29, 2026dnafoundation_modelgenomics+5

    Retrieval-augmented genomic foundation model that adds an explicit hash-based k-mer motif memory to transformer backbones, gaining up to 14% on functional genomics tasks.

    DNA & Gene
    83Openness