All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 217240 of 552 filtered models

  • CryoSiam

    201
    European Molecular Biology LaboratoryNovember 12, 2025convolutional_neural_networkcryo_etdenoising+8

    Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.

    Imaging
    64Openness
  • JWTH

    1
    Technical University of MunichNovember 7, 2025biomarker_detectioncancerfoundation_model+4

    Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.

    Pathology
    5Openness
  • Nona

    3
    GenentechNovember 6, 2025discrete_diffusionfoundation_modelfunctional_genomics+8

    Genomics foundation model that unifies sequence-to-function prediction, DNA language modeling, and generative regulatory design in one backbone.

    DNA & GeneRNA
    8Openness
  • EvoSynth

    8
    University of Alabama at BirminghamNovember 4, 2025autoencoderde_novo_designdiffusion+6

    Multi-target drug discovery framework pairing a diffusion-transformer generator with evolutionary latent-space search and synthesis-aware scoring.

    Small molecule
    51Openness
  • University of VirginiaNovember 4, 2025batch_correctioncell_type_annotationchromatin+7

    Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.

    Single-cellDNA & Gene
    32Openness
  • scLDM

    587
    Chan Zuckerberg InitiativeNovember 4, 2025autoencodercell_biologydata_augmentation+8

    Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.

    Single-cell
    75Openness
  • PLUTO-4

    2
    PathAINovember 4, 2025digital_pathologyfoundation_modelhistology+6

    Digital pathology foundation models from PathAI, spanning a 22M-parameter variant and a 1.1B-parameter flagship trained on 551K whole-slide images.

    Pathology
    19Openness
  • Chan Zuckerberg Initiative +1 otherNovember 2, 2025dnafoundation_modelgene_expression+4

    Hierarchical transformer with 1.2 billion parameters that predicts personalized gene expression from diploid genomes for variant effect prediction.

    DNA & Gene
    68Openness
  • GPFM

    12954
    Hong Kong University of Science and Technology +3 othersNovember 1, 2025cancer_diagnosisfeature_extractionfoundation_model+8

    Histopathology foundation model extracting general-purpose features from H&E patches by distilling the UNI, Phikon, and CONCH pathology encoders.

    Pathology
    84Openness
  • LSM-MS2

    Matterworks, Inc.October 30, 2025compound_annotationdisease_classificationembeddings+7

    Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.

    MetabolomicsSmall molecule
    4Openness
  • Pearl

    6
    Genesis Molecular AIOctober 28, 2025diffusiondrug_discoveryequivariant_neural_network+3

    Protein-ligand cofolding model that predicts 3D complex structures with SO(3)-equivariant diffusion, trained on physics-based synthetic data.

    Protein
    18Openness
  • OpenFold3

    7961
    Aqlaboratory +2 othersOctober 28, 2025diffusiondrug_discoveryfoundation_model+2

    Open-source Apache-2.0 reproduction of AlphaFold3 that predicts all-atom structures of proteins, RNA, DNA, small molecules, and their complexes.

    ProteinRNASmall molecule
    92Openness
  • LUNA

    131177.3K
    ETH ZurichOctober 25, 2025abnormality_detectionartifact_rejectioncross_attention+5

    EEG foundation model whose learned queries map any electrode montage into a fixed latent space, scaling linearly in the number of channels.

    Biosignals
    73Openness
  • Verily Life SciencesOctober 24, 2025cross_attentiondisease_risk_predictionelectronic_health_records+7

    Multimodal EHR foundation model that fuses polygenic risk scores into a GPT-2-style backbone by cross-attention for zero-shot disease risk prediction.

    Language modelDNA & Gene
    8Openness
  • Tahoe-x1

    1591539
    Tahoe TherapeuticsOctober 23, 2025cancercell_type_annotationdrug_discovery+7

    Perturbation-trained single-cell foundation models (up to 3B parameters) that jointly model genes, cells, and compounds for precision oncology tasks.

    Single-cellSmall molecule
    95Openness
  • MetaboFM

    2
    Georgia Institute of TechnologyOctober 23, 2025classificationfoundation_modelmass_spectrometry_imaging+6

    Vision Transformer foundation model for spatial metabolomics, pretrained on ~4,000 curated METASPACE mass spectrometry imaging datasets.

    MetabolomicsSpatial omicsImaging
    10Openness
  • CellTok

    Tsinghua UniversityOctober 22, 2025autoencodercell_cell_communicationcell_type_annotation+7

    Multimodal LLM that tokenizes single cells into discrete VQ-VAE codebook tokens, letting one model reason jointly over transcriptomes and text.

    Single-cellLanguage model
    20Openness
  • University of North Carolina at Chapel HillOctober 21, 2025behavior_predictionbrain_connectomedisease_diagnosis+6

    fMRI foundation model of the human brain connectome: 1.2B parameters and brain-environment interaction tokens for behavior and disease prediction.

    Biosignals
    26Openness
  • NeurIPT

    1111
    Xiamen University Malaysia +4 othersOctober 18, 2025brain_computer_interfaceseegeeg_decoding+8

    EEG foundation model for brain-computer interfaces, pairing masked pretraining with a mixture-of-experts transformer across electrode montages.

    Biosignals
    11Openness
  • CortexMAE

    532107
    Sophont +1 otherOctober 15, 2025brain_state_decodingfmrifoundation_model+5

    fMRI foundation model trained on cortical flat-map videos with masked autoencoding, showing power-law scaling on brain activity reconstruction.

    Biosignals
    68Openness
  • FlashRNA

    182
    Deep GenomicsOctober 15, 2025foundation_modelgene_expressiongenomics+4

    Efficient sequence-to-function transformer for regulatory genomics, matching Borzoi-class models while training in about a day on a single GPU.

    DNA & GeneRNA
    59Openness
  • Odyssey

    1
    AnthrogenOctober 15, 2025de_novo_designdiffusionfoundation_model+2

    Proprietary family of multimodal protein language models (up to 102B parameters) for sequence and structure generation, editing, and design.

    Protein
    13Openness
  • GeneJEPA

    355
    Biostate AIOctober 14, 2025cell_type_annotationfoundation_modelperturbation_prediction+2

    Self-supervised single-cell foundation model that predicts masked gene embeddings in latent space using a joint-embedding predictive architecture.

    Single-cell
    44Openness
  • FlexRibbon

    2
    Beijing Zhongguancun AcademyOctober 10, 2025diffusionfoundation_modelmultimodal+5

    Protein foundation model with 3B parameters, pretrained jointly on sequence and 3D structure via masked language modeling and diffusion denoising.

    Protein
    20Openness