All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 217–240 of 552 filtered models
CryoSiam
201—European Molecular Biology LaboratoryNovember 12, 2025convolutional_neural_networkcryo_etdenoising+8Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.
Imaging64OpennessJWTH
—1—Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.
Pathology5OpennessEvoSynth
8——Multi-target drug discovery framework pairing a diffusion-transformer generator with evolutionary latent-space search and synthesis-aware scoring.
Small molecule51OpennessAtacformer
28297Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.
Single-cellDNA & Gene32OpennessscLDM
587—Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.
Single-cell75OpennessVariantFormer
322—Hierarchical transformer with 1.2 billion parameters that predicts personalized gene expression from diploid genomes for variant effect prediction.
DNA & Gene68OpennessGPFM
12954—Hong Kong University of Science and Technology +3 othersNovember 1, 2025cancer_diagnosisfeature_extractionfoundation_model+8Histopathology foundation model extracting general-purpose features from H&E patches by distilling the UNI, Phikon, and CONCH pathology encoders.
Pathology84OpennessLSM-MS2
———Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.
MetabolomicsSmall molecule4OpennessPearl
—6—Protein-ligand cofolding model that predicts 3D complex structures with SO(3)-equivariant diffusion, trained on physics-based synthetic data.
Protein18OpennessOpenFold3
7961—Open-source Apache-2.0 reproduction of AlphaFold3 that predicts all-atom structures of proteins, RNA, DNA, small molecules, and their complexes.
ProteinRNASmall molecule92OpennessLUNA
131177.3KEEG foundation model whose learned queries map any electrode montage into a fixed latent space, scaling linearly in the number of channels.
Biosignals73Openness- Verily Life SciencesOctober 24, 2025cross_attentiondisease_risk_predictionelectronic_health_records+7
Multimodal EHR foundation model that fuses polygenic risk scores into a GPT-2-style backbone by cross-attention for zero-shot disease risk prediction.
Language modelDNA & Gene8Openness Tahoe-x1
1591539Perturbation-trained single-cell foundation models (up to 3B parameters) that jointly model genes, cells, and compounds for precision oncology tasks.
Single-cellSmall molecule95OpennessMetaboFM
—2—Georgia Institute of TechnologyOctober 23, 2025classificationfoundation_modelmass_spectrometry_imaging+6Vision Transformer foundation model for spatial metabolomics, pretrained on ~4,000 curated METASPACE mass spectrometry imaging datasets.
MetabolomicsSpatial omicsImaging10OpennessCellTok
———Multimodal LLM that tokenizes single cells into discrete VQ-VAE codebook tokens, letting one model reason jointly over transcriptomes and text.
Single-cellLanguage model20Openness- University of North Carolina at Chapel HillOctober 21, 2025behavior_predictionbrain_connectomedisease_diagnosis+6
fMRI foundation model of the human brain connectome: 1.2B parameters and brain-environment interaction tokens for behavior and disease prediction.
Biosignals26Openness NeurIPT
1111—EEG foundation model for brain-computer interfaces, pairing masked pretraining with a mixture-of-experts transformer across electrode montages.
Biosignals11OpennessFlashRNA
182—Efficient sequence-to-function transformer for regulatory genomics, matching Borzoi-class models while training in about a day on a single GPU.
DNA & GeneRNA59OpennessGeneJEPA
355—Self-supervised single-cell foundation model that predicts masked gene embeddings in latent space using a joint-embedding predictive architecture.
Single-cell44OpennessFlexRibbon
—2—Protein foundation model with 3B parameters, pretrained jointly on sequence and 3D structure via masked language modeling and diffusion denoising.
Protein20Openness