All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 125 filtered models
RVQ-Alpha
———Single-cell foundation model that tokenizes scRNA-seq into 10 tokens in a Qwen3-4B vocabulary for cell type annotation and perturbation prediction.
Single-cell4OpennessRNABag
———HomiGen Intelligence Technology Co., Ltd.April 22, 2026cancer_detectioncell_type_annotationfoundation_model+6Transcriptome foundation model for precision oncology, generalizing zero-shot across tissue, plasma cfRNA, and tumor-educated platelet modalities.
Single-cell46OpennessxVERSE
———Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.
Single-cell10OpennessscLong
2210—Billion-parameter single-cell foundation model with self-attention over 28,000 human genes, adding Gene Ontology priors via a graph neural network.
Single-cell29OpennessRegFormer
———Single-cell foundation model combining regulatory network priors with a Mamba backbone for clustering, batch integration, and perturbation modeling.
Single-cell10OpennessCLOP-DiT
———Generates single-cell transcriptomes from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.
Single-cell10OpennessLingshu-Cell
—3—Virtual cell model using masked discrete diffusion over the whole transcriptome to simulate scRNA-seq perturbation responses across tissues.
Single-cell21OpennessRNAGAN
1——Generative adversarial network trained on single-cell and bulk RNA-seq for sample stratification, marker analysis, and synthetic data generation.
Single-cell60OpennessSCALE
———Virtual cell foundation model predicting single-cell responses to genetic, chemical, and cytokine perturbations with conditional flow matching.
Single-cell19OpennessX-Cell
1068—Diffusion language model with 4.9 billion parameters that predicts genome-wide CRISPRi perturbation responses in single-cell transcriptomes.
Single-cell20OpennessSpatialFusion
40——Multimodal foundation model integrating spatial transcriptomics, H&E histopathology, and pathway scores for single-cell niche discovery.
Spatial omicsSingle-cellPathology71OpennessAetherCell
202—Generative virtual-cell model predicting whole-transcriptome responses to unseen compounds and genetic perturbations, from cell lines to organoids.
Single-cellSmall molecule29OpennessHitAnno
———Hierarchical language model for atlas-level cell-type annotation of scATAC-seq data that annotates new query datasets without retraining.
Single-cell14OpennessPerturbGen
25——Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cell trajectories over time.
Single-cell72OpennessCellPace
———Temporal diffusion framework for single-cell developmental dynamics, interpolating and forecasting cell states from irregularly sampled time series.
Single-cell9OpennessMAP
———Shanghai Jiao Tong UniversityFebruary 25, 2026contrastive_learningdrug_response_predictiongraph_neural_network+6Knowledge-graph-grounded model that predicts single-cell transcriptomic responses to small molecules, with zero-shot prediction for unprofiled drugs.
Single-cellSmall molecule12OpennessCellAwareGNN
—1—Vanderbilt University Medical CenterFebruary 23, 2026drug_discoveryfoundation_modelgraph_neural_network+4Knowledge-graph foundation model for drug repurposing, grounding a biomedical graph in cell-type-specific genetic associations to rank indications.
Single-cellSmall molecule11OpennessPerturbDiff
547—Diffusion model predicting single-cell responses to genetic or drug perturbations, generating over distributions to capture population variability.
Single-cell51OpennessSingle-cell foundation model applying discrete diffusion directly to scRNA-seq counts, generating unconditional and perturbation-conditioned profiles.
Single-cell10OpennessCLM-X
———Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.
Single-cell4OpennessevoCancerGPT
———Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.
Single-cell11OpennessSTPAINTER
———University of Science and Technology of China +2 othersFebruary 13, 2026cancerdiffusionfoundation_model+4Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.
Spatial omicsSingle-cell4OpennessEVA
——89Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessscDFM
447—Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.
Single-cell54Openness