Open research repository operated by CERN, hosting DOI-citable, versioned model weights archived alongside the papers that describe them.
Protein language model pretrained on UniRef90 with masked language modeling and Gene Ontology annotation prediction, at 16 million parameters.
Geometric relational graph neural network that encodes 3D protein structures through geometry-aware message passing and self-supervised pretraining.
Microsoft Research / Microsoft Research AI for Science / University of Toronto / Stanford University
Released September 12, 2023
Discrete diffusion model for protein sequence and MSA generation, enabling controllable de novo design directly in sequence space without structure.
Harvard Medical School / Dana-Farber Cancer Institute / Brigham and Women's Hospital / Massachusetts General Hospital / Maastricht University / Aarhus University / Stanford University
Released March 15, 2024
Self-supervised 3D CT foundation model that extracts general-purpose tumor representations for cancer imaging biomarker discovery and prognosis.
RNA 3D structure prediction pipeline pairing a transformer (RNAformer) that predicts inter-nucleotide geometries with Rosetta energy minimization.
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