Yonsei University

Designs RNA and DNA aptamers against protein targets by backpropagating binding and anti-binding objectives through a frozen all-atom predictor.

Structure-based drug design model generating 3D ligands in protein pockets under gradient guidance for affinity, synthesizability, and selectivity.

Spatiotemporal foundation model that learns representations directly from 4D functional MRI volumes for disease diagnosis and phenotype prediction.

Retinal fundus foundation model conditioned on patient age and sex, pretrained on 1.0 million colour photographs from 292,000 patients.

Functional MRI foundation model that learns brain dynamics as a stochastic optimal control problem, self-supervised on 41,072 UK Biobank subjects.

Conditional GAN that generates small molecules against a protein-protein interaction interface, encoding the complex with graph attention networks.