University of Freiburg

RNA-protein complex refinement via diffusion, repositioning the protein against the RNA to improve AlphaFold 3 and ProRNA3D-single backbones.

Deep mutational scanning score imputation across protein domains, pairing ESM-1v embeddings with EVE conservation and physicochemical features.

RNA folding kinetics model that predicts the full distribution of first passage times from a few simulated examples in a single forward pass.

Inverse RNA folding from contact maps: an axial-attention transformer designing sequences for pseudoknots, non-canonical pairs and multiplets.

RNA secondary structure prediction from a single sequence, without MSAs. Axial-attention transformer reaching F1 0.764 on the TS-PDB benchmark.

Multi-task pretrained biomedical imaging model whose frozen features match ImageNet fine-tuning on CT, X-ray and histology tasks from 1% of labels.